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    BRCA1-associated RING domain protein 1 is a protein that in humans is encoded by the BARD1 gene. The human BARD1 protein is 777 amino acids long and contains a RING finger domain (residues 46-90), four ankyrin repeats (residues 420-555), and two tandem BRCT domains (residues 568-777). See more

    Most, if not all, BRCA1 heterodimerizes with BARD1 in vivo. BARD1 and BRCA1 form a heterodimer via their N-terminal RING finger domains. The BARD1-BRCA1 interaction is observed in vivo and in vitro and is essential for … See more

    BARD1 has been shown to interact with:
    • AURKB,
    • BCL3,
    • See more

    • Human BARD1 genome location and BARD1 gene details page in the UCSC Genome Browser.
    • Overview of all the structural information available in the See more

    Overview image

    If a cancer cell's capacity to repair DNA damage were incapacitated, cancer treatments would be more effective. Inhibiting cancer cells' BRCA1/BARD1 heterodimer from … See more

    • Irminger-Finger I, Leung WC (Jun 2002). "BRCA1-dependent and independent functions of BARD1". The International Journal of … See more

     
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  3. Studies of BARD1 wikipedia
  4. BARD1 Gene Mutations: Risk, Management and Treatment

  5. BARD1 reads H2A lysine 15 ubiquitination to direct homologous …

  6. WEBMay 1, 2006 · BRCA1-associated ring domain 1 (BARD1) is the main binding partner of BRCA1 and is essential for the tumour-suppressor functions of BRCA1. The BARD1–BRCA1 heterodimer has ubiquitin …

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  7. The Fundamental Role of BARD1 Mutations and Their …

    WEBJul 14, 2022 · BRCA1-associated RING domain 1 (BARD1) is the name of a protein that Wu et al. in 1996 found as a BRCA1 (BReast CAncer type 1) binding partner [ 1 ]. Here, we shifted our focus to the BARD1 as a …

  8. BRCA1 - Wikipedia

  9. A synergetic effect of BARD1 mutations on tumorigenesis

  10. Bard - Wikipedia

  11. Gene Mutation BARD1 and Cancer Risk - Everyday Health

  12. The antitumorigenic roles of BRCA1–BARD1 in DNA repair and

  13. Entry - *601593 - BRCA1-ASSOCIATED RING DOMAIN 1; …

  14. The Function of BARD1 in Centrosome Regulation in Cooperation …

  15. Dualistic Role of BARD1 in Cancer - PMC - National Center for ...

  16. The Effects of Genetic and Epigenetic Alterations of BARD1 on …

  17. Dualistic Role of BARD1 in Cancer - PubMed