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- diethylstilbestrol (DES), nonsteroidal synthethic estrogen used as a drug and formerly used to promote growth of livestock. Unlike natural estrogens, DES remains active following oral administration. It is also administered as vaginal suppositories and by injection. DES breaks down more slowly in the body than do the natural estrogens.
www.britannica.com/science/diethylstilbestrol - See more
See all on WikipediaDiethylstilbestrol - Wikipedia
Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication, which is presently rarely used. In the past, it was widely used for a variety of indications, including pregnancy support for those with a history of recurrent miscarriage, hormone therapy for menopausal … See more
DES has been used in the past for the following indications:
• Recurrent miscarriage in pregnancy
• See moreAt more than 1 mg/day, DES is associated with high rates of side effects including nausea, vomiting, abdominal discomfort, headache, … See more
DES belongs to the stilbestrol (4,4'-dihydroxystilbene) group of compounds. It is a nonsteroidal open-ring analogue of the steroidal See more
Alan Turing, the ground-breaking cryptographer, founder of computing science and programmable computers, who also proposed the actual theoretical model of biological … See more
DES has been assessed in the past in clinical studies at extremely high doses of as much as 1,500 to 5,000 mg/day. See more
Synthesis
DES was first synthesized in early 1938 by Leon Golberg, then a graduate student of Sir Robert Robinson at the Dyson Perrins Laboratory at … See moreWikipedia text under CC-BY-SA license Birth defects of diethylstilbestrol - Wikipedia
Diethylstilbestrol (DES), a synthetic nonsteroidal estrogen which was previously used clinically to support pregnancy, has been linked to a variety of long-term adverse effects in women who were treated with it during pregnancy and in their offspring.
Wikipedia · Text under CC-BY-SA license- Estimated Reading Time: 10 mins
Diethylstilbestrol dipropionate - Wikipedia
WEB[1] [2] It is an ester of diethylstilbestrol with propionic acid, [1] and is more slowly absorbed in the body than diethylstilbestrol. [3] The medication has been said to be one of the most …
Are the Effects of DES Over? A Tragic Lesson from the Past
WEBSep 30, 2021 · Diethylstilbestrol (DES), a transplacental endocrine-disrupting chemical, was prescribed to pregnant women for several decades. The number of women who took …
DIETHYLSTILBESTROL - Pharmaceuticals - NCBI Bookshelf
WEBDiethylstilbestrol is a synthetic non-steroidal estrogen that was historically widely used to prevent potential miscarriages by stimulating the synthesis of estrogen and …
Diethylstilbestrol: Uses, Interactions, Mechanism of …
WEBA synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report...
Diethylstilbestrol | C18H20O2 | CID 448537 - PubChem
WEBDiethylstilbestrol is an olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.
Diethylstilbestrol - 15th Report on Carcinogens - NCBI Bookshelf
WEBDec 21, 2021 · Diethylstilbestrol is known to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in humans.
WEBDiethylstilbestrol caused tumors in several animal species, by sev eral different routes of exposure, and at several different tissue sites (primarily estrogensensitive organs and …
DES Exposure: Questions and Answers | American Cancer Society
WEBDES (diethylstilbestrol) is a man-made (synthetic) form of estrogen, a female hormone. Doctors prescribed it from 1938 until 1971 to help some pregnant women who had had …
Diethylstilbestrol syndrome | About the Disease | GARD
WEBDiethylstilbestrol syndrome (DES syndrome) refers to developmental or health problems caused by exposure to DES before birth (in utero), such as reproductive tract …
Diethylstilbestrol (DES) in the US | Embryo Project Encyclopedia
WEBMar 23, 2015 · Diethylstilbestrol (DES) is an artificially created hormone first synthesized in the late 1930s. Doctors widely prescribed DES first to pregnant women to prevent …
Diethylstilbestrol | SpringerLink
WEBJan 1, 2017 · Diethylstilbestrol (DES), first manufactured by Dodds and associates in London in 1938, was used to treat several gynecologic conditions. In particular, it was …
Stilbestrol - Wikipedia
WEBStilbestrol, or stilboestrol, also known as 4,4'-dihydroxystilbene or 4,4'-stilbenediol, is a stilbenoid nonsteroidal estrogen [1] and the parent compound of a group of more potent …
Diethylstilbestrol (DES) | Britannica
WEBDiethylstilbestrol (DES), nonsteroidal synthethic estrogen used as a drug and formerly used to promote growth of livestock. Unlike natural estrogens, DES remains active …
D.E.S is it | Diethylstilbestrol syndrome (DES)
WEBDES is a non-steroidal synthetic estrogen that was widely prescribed to pregnant women between 1940 and 1977 to prevent miscarriage and premature birth. DES was sold in …
Diethylstilbestrol: Indications, Side Effects, Warnings - Drugs.com
WEBMar 1, 2024 · Easy-to-read patient leaflet for Diethylstilbestrol. Includes indications, proper use, special instructions, precautions, and possible side effects.
Diethylstilbestrol | Macmillan Cancer Support
WEBDiethylstilbestrol is a hormonal therapy drug used to treat advanced prostate cancer when other treatments are not suitable or no longer working. It is best to read this information …
Diethylstilbestrol | Drugs | BNF | NICE
WEBView diethylstilbestrol information, including dose, uses, side-effects and pregnancy.
Fosfestrol - Wikipedia
WEBFosfestrol, sold under the brand name Honvan and also known as diethylstilbestrol diphosphate (DESDP), is an estrogen medication which is used in the treatment of …
Diethylstilbestrol. Diethylstilbestrol side effects at Patient
WEBMar 20, 2022 · Diethylstilbestrol is an oestrogen hormone treatment which helps to control the symptoms of some cancers. It is sometimes used to treat prostate cancer , …
Diethylstilbestrol dipalmitate - Wikipedia
WEBDiethylstilbestrol dipalmitate (brand names Palmestril, Stilpalmitate), also known as stilpalmitate, is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of …
Dimethylstilbestrol - Wikipedia
WEBDimethylstilbestrol (DMS) is a nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol which was never marketed.: 213 It is a so-called "weak", "impeded", or …
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