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FANCD2 - Wikipedia
Fanconi anemia group D2 protein is a protein that in humans is encoded by the FANCD2 gene. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2 (this gene), FANCE, FANCF, FANCG, FANCI , FANCJ, FANCL, … See more
Fanconi anemia is a disorder with a recessive Mendelian pattern of inheritance characterized by chromosomal instability, hypersensitivity to DNA crosslinking agents, increased See more
Tobacco smoke suppresses the expression of FANCD2, which codes for a DNA damage "caretaker" or repair mechanism. See more
• Hejna JA, Timmers CD, Reifsteck C, Bruun DA, Lucas LW, Jakobs PM, et al. (May 2000). "Localization of the Fanconi anemia complementation group D gene to a 200-kb region on chromosome 3p25.3". American Journal of Human Genetics. 66 (5): 1540–51. See more
Humans with a FANCD deficiency display hypogonadism, male infertility, impaired spermatogenesis, and reduced female fertility. Similarly, mice deficient in FANCD2 show … See more
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FANCA - Wikipedia
WEBThe Fanconi anaemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, …
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FANCD2 Gene - GeneCards | FACD2 Protein | FACD2 Antibody
FANCD2 - My Cancer Genome
The Fanconi Anemia/BRCA Pathway: FANCD2 at the …
WEBAvailable data indicate that FANCD2 is involved in cell cycle regulation and DNA repair. Our current knowledge on the functional significance of FA pathway and more specifically FANCD2 and its interacting proteins in …
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FANCD2 modulates the mitochondrial stress response to prevent …
FANCD2 and DNA Damage - PMC - National Center for …
FANCD2–FANCI is a clamp stabilized on DNA by
WEBFeb 17, 2020 · Together, our work suggests that FANCD2–FANCI is a clamp that is locked onto DNA by ubiquitin, with distinct interfaces that may recruit other DNA repair factors.
Mechanism, specificity, and function of …
WEBJun 17, 2021 · Fanconi anemia (FA) is a rare genetic disorder caused by mutations in any of the currently 22 known FA genes. The products of these genes, along with other FA-associated proteins, participate in a ...
FANCD2 FA complementation group D2 [ (human)] - National …
FANCD2 and DNA Damage - PubMed
Differential functions of FANCI and FANCD2 ubiquitination …
FANCI - Wikipedia
Mechanism, specificity, and function of FANCD2-FANCI
Fancd2 in vivo interaction network reveals a non-canonical role in ...
Ferroptosis regulator FANCD2 is associated with immune …
FANCB - Wikipedia
FBXL12 degrades FANCD2 to regulate replication recovery
DNA clamp function of the monoubiquitinated Fanconi anaemia …
FANCD2OS - Wikipedia
FANCL - Wikipedia
The DNA-damage kinase ATR activates the FANCD2-FANCI …
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