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- The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune system. The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes.Learn more:The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune system. The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes.en.wikipedia.org/wiki/Interleukin-3_receptorThe Interleukin-3 receptor is a cell surface receptor that is involved in the stimulation of macrophages, granulocytes, and dendritic cells production from bone marrow precursors. It shares a common β-subunit with GM-CSF and IL-5 receptors.www.sciencedirect.com/topics/neuroscience/interle…Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (C luster of D ifferentiation 123), is a human gene. [5] The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor.en.wikipedia.org/wiki/IL3RA
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Interleukin-3 receptor - Wikipedia
The interleukin-3 receptor (CD123) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune system. The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes. The receptor belongs to the type I cytokine … See more
The receptor, found on pluripotent progenitor cells, induces tyrosine phosphorylation within the cell and promotes proliferation and differentiation within the hematopoietic cell lines. It can be found on See more
• Interleukin-3+Receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) See more
Tagraxofusp, human IL-3 fused to diphtheria toxin, is an approved treatment for BPDCN. An experimental antibody-drug conjugate SGN-CD123A targets CD123 as a possible treatment for AML. See more
Wikipedia text under CC-BY-SA license Interleukin 3 - Wikipedia
IL-3 is a T cell-derived, pluripotent and hematopoietic factor required for survival and proliferation of hematopoietic progenitor cells. The signal transmission is ensured by high affinity between cell surface interleukin-3 receptor and IL-3. This high affinity receptor contains α and β subunits. IL-3 shares the β subunit with IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF). This β subunit sharing explains the biological functional similarities of different hematopoietic gr…
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IL3RA - Wikipedia
Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (C luster of D ifferentiation 123), is a human gene. [5] The protein encoded by this gene is an interleukin 3 …
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Interleukin-3 Receptor - an overview | ScienceDirect Topics
The Interleukin-3 receptor is a cell surface receptor that is involved in the stimulation of macrophages, granulocytes, and dendritic cells production from bone marrow precursors. It …
Interleukin-3 receptor — Википедија
Interleukin-3 receptor (takođe poznat kao CD123 antigen) je molekul nađen na ćelijama koje pomažu prenos interleukin-3 signala, rastvornog citokina važnog za imunski sistem. Gen koji …
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Interleukin-3 receptor – Wikipedija/Википедија
Interleukin-3 receptor (takođe poznat kao CD123 antigen) je molekul nađen na ćelijama koje pomažu prenos interleukin-3 signala, rastvornog citokina važnog za imunski sistem. Gen koji …
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Interleukin 3 - an overview | ScienceDirect Topics
Interleukin-3 (IL-3) is a cytokine of the beta common family—including IL-5 and granulocyte macrophage colony-stimulating factor—which stimulates proliferation and differentiation of a …
Interleukin-3 in hematology and oncology: current state of
Interleukin (IL)-3 is a multipotent hematopoietic growth factor produced by activated T cells, monocytes/macrophages and stroma cells. The human IL-3 gene is located on chromosome 5 …
白细胞介素-3 - 维基百科,自由的百科全书
白细胞介素3是 白介素,一个类生物信号(细胞因子)的一种,作为人体免疫系统一部分增强对于疾病的天然响应。 通过结合 白介素-3受体 (英语:Interleukin-3 receptor) 发挥效应。 白细 …
Interleukin - Wikipedia
There are many receptors on the surface membrane capable of binding IL-8; the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression …
Interleukin 3 - an overview | ScienceDirect Topics
Interleukin-3 (IL-3) is a cytokine that binds to a receptor composed of IL-3Rα and βc subunits, stimulating the growth of various progenitor cells and promoting the survival of macrophages, …
A dual role for the N-terminal domain of the IL-3 receptor in cell ...
Jan 26, 2018 · The interleukin-3 (IL-3) receptor is a cell-surface heterodimer that links the haemopoietic, vascular and immune systems and is overexpressed in acute and chronic …
Structural and evolutionary exploration of the IL-3 family and its ...
Interleukin-3 (IL-3) is a cytokine belonging to the family of common β (βc) and is involved in various biological systems. Its activity is mediated by the interaction with its receptor (IL-3R), a …
IL-3: key orchestrator of inflammation - PMC - PubMed Central …
Interleukin (IL)-3 has long been known for its hematopoietic properties. However, recent evidence has expanded our understanding of IL-3 function by identifying IL-3 as a critical orchestrator of …
Interleukin receptor - Wikipedia
Interleukin receptors are a family of cytokine receptors for interleukins. They belong to the immunoglobulin superfamily.
Interleukin 3 Receptor - an overview | ScienceDirect Topics
Interleukin-3 (IL-3) is a cytokine of the beta common family—including IL-5 and granulocyte macrophage colony-stimulating factor—which stimulates proliferation and differentiation of a …
IL-3 receptor expression, regulation and function in cells of the ...
Recent evidence suggests that the target cell population of IL-3 is not restricted to haemopoietic cells as previously thought, but vascular cells such as endothelial cells also express receptors …
IL2RA - Wikipedia
The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha …
Interleukin-3 Receptor - an overview | ScienceDirect Topics
The granulocyte/macrophage CSF (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors are a subfamily of class I hematopoietin receptors. They have unique ligand-binding alpha chains …
Interleukin 20 receptor, alpha subunit - Wikipedia
Interleukin 20 receptor, alpha subunit, is a subunit of the interleukin-20 receptor, the interleukin-26 receptor, and the interleukin-24 receptor. [5] The interleukin 20 receptor, alpha subunit is also …
Interleukin 3 Receptor - an overview | ScienceDirect Topics
The interleukin 3 receptor (IL-3R) system, including IL-3R, interleukin 5 receptor (IL-5R) and granulocyte–macrophage colony-stimulating factor receptor (GM-CSFR), regulates the …
Interleukin-3 Receptor - an overview | ScienceDirect Topics
Interleukin-3 (IL-3) is a cytokine that simulates hematopoiesis along multiple lineages. IL-3 receptors are present on macrophages, basophils, eosinophils. Juvenile rhesus macaques …
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