McKinnon was born and raised on Long Island in the town of Sea Cliff, New York, to Laura Campbell, a parent educator, and Michael Thomas Berthold, an architect. She has a younger sister, comedian Emily Lynne, wit… See more

In 2007, McKinnon joined the original cast of Logo TV's The Big Gay Sketch Show, where she was a cast member for all three seasons.
Since 2008, she has performed live sketch comedy re… See more

While attending Columbia University, she dated future journalist Bari Weiss. McKinnon was in a relationship with photographer and actress Jackie Abbott from 2016 to 2019. While presenting Ellen DeGeneres with … See more