These medications are used in the treatment of many conditions, such as:
• Dyspepsia
• Peptic ulcer disease including after endoscopic treatment for bleeding
• As part of Helicobacter pylori eradication therapy … See more

In general, proton pump inhibitors are well tolerated, and the incidence of short-term adverse effects is relatively low. The range and occurrence of adverse effects are similar for all of the PPIs, though they have been reported m… See more

Proton pump inhibitors act by irreversibly blocking the hydrogen/potassium adenosine triphosphatase enzyme system (the H /K ATPase, or, more commonly, the gastric proton pump) of the gastric parietal cells. The proton … See more