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- Pyrimidine dimers, also known as thymine dimers, are molecular lesions that originate from thymine or cytosine bases within DNA. They are formed by a photochemical reaction when exposed to ultraviolet light, causing two consecutive bases on one strand to bind together and disrupting the normal base-pairing double-strand structure in that area. These cross-linking events can lead to DNA mutations and are associated with skin cancers12.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.The photon causes two consecutive bases on one strand to bind together, destroying the normal base-pairing double-strand structure in that area. Pyrimidine dimers represent molecular lesions originating from thymine or cytosine bases within DNA, resulting from photochemical reactions.en.wikipedia.org/wiki/Pyrimidine_dimerPyrimidine dimers Pyrimidine dimers (also known as thymine dimers) are formed by a photochemical reaction from pyrimidine DNA bases when exposed to ultraviolet light. This cross-linking causes DNA mutations, which can be carcinogenic, causing skin cancers.en.wikipedia.org/wiki/Dimerization_(chemistry)
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Pyrimidine dimer - Wikipedia
Pyrimidine dimers represent molecular lesions originating from thymine or cytosine bases within DNA, resulting from photochemical reactions. These lesions, commonly linked to direct DNA damage, are induced by ultraviolet light (UV), particularly UVC, result in the formation of covalent bonds … See more
Pyrimidine dimers encompass several types, each with distinct structures and implications for DNA integrity.
Cyclobutane … See moreMutagenesis, the process of mutation formation, is significantly influenced by translesion polymerases which often introduce mutations … See more
Direct DNA damage is reduced by sunscreen, which also reduces the risk of developing a sunburn. When the sunscreen is at the … See more
Pyrimidine dimers introduce local conformational changes in the DNA structure, which allow recognition of the lesion by repair enzymes. In most organisms (excluding See more
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