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Telomerase - Wikipedia
Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most eukaryotes. Telomeres protect the end of the chromosome from … See more
The existence of a compensatory mechanism for telomere shortening was first found by Soviet biologist Alexey Olovnikov in 1973, who also suggested the telomere hypothesis of See more
The molecular composition of the human telomerase complex was determined by Scott Cohen and his team at the Children's Medical Research Institute (Sydney Australia) and consists of two molecules each of human telomerase reverse transcriptase See more
• The Immortal Cell, by Michael D. West, Doubleday (2003) ISBN 978-0-385-50928-2 See more
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Telomere - Wikipedia
During DNA replication, DNA polymerase cannot replicate the sequences present at the 3' ends of the parent strands. This is a consequence of its unidirectional mode of DNA synthesis: it can only attach new nucleotides to an existing 3'-end (that is, synthesis progresses 5'-3') and thus it requires a primer to initiate replication. On the leading strand (oriented 5'-3' within the replication fork), D…
Wikipedia · Text under CC-BY-SA licenseTelomeres in the cell cycle - Wikipedia
- Because eukaryotic chromosomes are linear and because DNA replication by DNA polymerase requires the presence of an RNA primer that is later degraded, eukaryotic cells face the end-replication problem. This problem makes eukaryotic cells unable to copy the last few bases on the 3’ end of the template DNA strand, leading to chromosome—and, therefore...
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Telomerase - Simple English Wikipedia, the free encyclopedia
Telomerase is an RNA protein which is an enzyme. It adds DNA sequence repeats (" T T A G G G " in all vertebrates) to the end of DNA strands in the telomere regions. The telomeres are …
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Telomerase: Definition, Function, Structure and …
Jul 25, 2017 · Telomerase is an enzyme found inside our cells, which may be related to the aging process. It adds short, repetitive “caps” to our DNA …
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Telomerase – Wikipedia tiếng Việt
Telomerase là một ribonucleoprotein bổ sung chuỗi lặp lại telomere phụ thuộc vào loài vào đầu 3' của telomere.Một telomere là một khu vực bao gồm các chuỗi lặp đi lặp lại ở mỗi đầu của nhiễm sắc thể nhân chuẩn ở hầu hết các sinh vật …
Telomerase | Description, Function, & Facts | Britannica
telomerase, enzyme that influences cell life span by adding organic compounds known as nucleotides to telomeres, segments of DNA located at the ends of chromosomes. Telomeres consist of repetitive DNA sequences wherein the …
Overview | Telomerase Database
Discovered by Carol Greider and Liz Blackburn in 1985, telomerase is a unique ribonucleoprotein (RNP) enzyme that adds telomeric repeats to the 3' end of chromosomes to counteract the …
Telomerase RNA component - Wikipedia
Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres. [3] [4] TERC serves …
Telomere
4 days ago · Telomeres are how cells protect chromosome ends. The telomere itself is a long stretch of a specific short DNA sequence repeated over and over hundreds of times. At the very end of the telomere is a sort of knot not called …
Structural Biochemistry/Nucleic Acid/DNA/DNA structure/Telomeres
Telomeres (from the Greek telos, "an end") are long stretches of repeating non-coding DNA sequences at the ends of the DNA strand. They protect the ends of DNA and prevent DNA …
Telomerase - Wikipedia
Telomerase is een enzym dat in de celkern van bepaalde cellen voorkomt. Het bestaat voor een deel uit proteïne en voor een deel uit RNA . De proteïne is een enzym, een reverse …
Definition of telomerase - NCI Dictionary of Cancer Terms
An enzyme in cells that helps keep them alive by adding DNA to telomeres (the ends of chromosomes). Each time a cell divides, the telomeres lose a small amount of DNA and …
Telomerase – Wikipedia
Die Telomerase ist ein Enzym des Zellkerns, welches aus einem Protein- (TERT) und einem langen RNA-Anteil (TR) besteht und somit ein Ribonukleoprotein ist. Dieses Enzym stellt die …
Composition and Function of Telomerase—A Polymerase …
In this review, we focus on the structure, composition and function of telomerases. In addition, we discuss the origin and phylogenetic divergence of this unique RNA-dependent DNA …
Relationship between telomeres and longevity - Wikipedia
Many organisms have a ribonucleoprotein enzyme called telomerase, which is responsible for adding repetitive nucleotide sequences to the ends of DNA. Telomerase replicates the …
Telomerase - an overview | ScienceDirect Topics
Telomerase is a ribonucleoprotein (RNP) responsible for the maintenance of chromosomal integrity by stabilizing telomere length. Telomerase is a widely expressed hallmark responsible …
Telomerase – Structure, Mechanism, Regulation, Functions
Dec 23, 2024 · Telomerase (terminal transferase) is a ribonucleoprotein enzyme that extends telomeres, the repetitive nucleotide sequences at the ends of eukaryotic chromosomes. …
What are telomeres? - Mechanobiology Institute, National …
Nov 30, 2023 · Telomeres are short nucleotide sequences found at the end of linear chromosomes which protect the genetic information. In vertebrates, telomeres have the …
Alternative Lengthening of Telomeres - Wikipedia
Alternative Lengthening of Telomeres (also known as "ALT") is a telomerase-independent mechanism by which cancer cells avoid the degradation of telomeres.
Telomerase - Telomeres - Wiley Online Library
Jun 21, 2024 · This chapter is mainly dedicated to the structure of telomerase and its mechanism of action. The catalytic core of telomerase consists of the TERT (TElomerase Reverse …
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