On January 20, Trusova was officially named to the Russian Olympic team. Competing in the women's event short program at the 2022 Winter Olympics, Trusova fell on an underrotated triple Axel attempt and received an edge call on her triple flip but still placed fourth in the segment, 5.24 points behind third-place Kaori Sakamoto. In the free program, Trusova landed all five of the quads planned in her program, albeit receiving an edge call on her quad flip and negative grade of execution on her quad toe-loop and final solo quad Lutz. Trusova became the first woman to land a quad flip and land a quad Lutz at the Olympics, the first woman to land four and five quads in competition, as well as the first woman to land four and five quads in one program at the Olympics. She won the silver medal behind Valieva.
Figure skating at the 2022 Winter Olympics – Women's singles
Trusova was selected to compete for the Russian Federation at the 2021 World Championships in March 2021 in Stockholm, where she was considered a favorite to make the podium. In the short program, Trusova placed twelfth after putting a hand down on her triple Lutz due to overrotation, consequently failing to execute the second part of her jump combination. In her free skate, she attempted five quads, falling on two of them; however, due to the high base value of her program, mistakes by other medal contenders, and her successful landing of three of her quads, Trusova was able to finish third overall for the bronze medal, 8.57 points ahead fourth-place skater Karen Chen. On the podium alongside Shcherbakova and Tuktamysheva, this was only the second time that a single country had swept the women's podium at the World Championships, after the United States in 1991. In early March 2022, the ISU banned all figure skaters and officials from Russia and Belarus from attending the World Championships due to the Russia's full-scale invasion of Ukraine in late February, as a result of which Trusova was not allowed to participate in the competition at the end of March.
World Figure Skating Championships
Competing at the 2020 European Championships, Trusova doubled and turned out of a planned triple Axel. In the free skate, she fell on two planned quads but landed her quad toe-triple toe combination successfully. She won the bronze medal behind Shcherbakova and Kostornaia. At the European Championships in Tallinn, Trusova placed third in the short program despite falling on her triple Axel attempt again. She landed two out of her four planned quads in the free skate, winning her second European bronze medal.
European Figure Skating Championships
Trusova's results qualified her for the Grand Prix Final in Torino. Skating in the short program, Trusova opted to attempt the triple Axel in competition for the first time but underrotated it and fell. Trusova said that the decision to introduce the triple Axel had been taken in light of its being landed "more or less consistently" in practices in the preceding week and remarked, "I like to risk, and without risking, I wouldn’t achieve what I have by this moment". In the free skate, Trusova attempted the quad flip in competition for the first time, landing it cleanly, alongside a quad Lutz and a quad toe loop, but doubled an intended quad Salchow and fell on a second quad toe attempt. She became the first female skater to attempt five quads in a free skate and the first to attempt four different types of quads. She won the bronze medal behind Shcherbakova and Kostornaia.
Grand Prix of Figure Skating Final
In March 2018, Trusova competed at the 2018 Junior Worlds, where she won the gold medal after placing first in both the short program and free skate. Her free skate score of 153.49 points set the new world record for the junior free program, and her total score of 225.52 points was also the new world record for the junior combined total score. At the competition, Trusova became the first female skater to land the quad toe loop, the second to land the quad Salchow behind Miki Ando, and the first to land two ratified quads in a free skate. Her quadruple jump was the first ratified in 16 years since Ando's in 2002. Trusova successfully defended her Junior World title at the 2019 World Junior Championships, placing second in the short program to Shcherbakova and winning the free skate.
World Junior Figure Skating Championships