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- This review will describe the genomic and epigenetic features of alpha satellite DNA, discuss recent findings of noncoding transcripts produced from distinct alpha satellite arrays, and address current progress in the functional understanding of this oft-neglected repetitive sequence.Learn more:This review will describe the genomic and epigenetic features of alpha satellite DNA, discuss recent findings of noncoding transcripts produced from distinct alpha satellite arrays, and address current progress in the functional understanding of this oft-neglected repetitive sequence.pmc.ncbi.nlm.nih.gov/articles/PMC6121732/Recent advances in understanding the structure and evolution of human and other primate alpha satellites are summarized in this review. Alpha satellite is one of the most thoroughly studied repetitive DNA families and is a paradigm for understanding other satellite DNA and multigene families.pubmed.ncbi.nlm.nih.gov/1822282/
Alpha satellite DNA biology: Finding function in the recesses of …
This review will describe the genomic and epigenetic features of alpha satellite DNA, discuss recent findings of noncoding transcripts produced from distinct alpha satellite arrays, and address current progress in the functional understanding of this oft-neglected repetitive sequence.
See results only from pmc.ncbi.nlm.nih.govSequence, Chromatin and E…
Here we describe the different classes of satellite DNA sequences, their satellite …
Genomic Tackling of Huma…
Additionally, the centromeric alpha (α) satellite DNA family was also identified …
Evolution of alpha satellite - …
Recent advances in understanding the structure and evolution of human and …
Genomic variation within alp…
Our study demonstrates that genomic variation within highly repetitive, …
Alpha-satellite DNA of prima…
In this report we review alpha-satellite DNA (AS) sequence data to support the …
Repetitive Fragile Sites: Cen…
The novel connection between alpha-satellite DNA instability and human …
Review Dynamic interplay between human alpha-satellite DNA …
Mar 15, 2024 · Here, we review evidence of meiotic selection operating to mitigate centromere drive, as well as recent reports on centromere damage, recombination and repair during the …
- Studies of alpha satellite dna review
Sequence, Chromatin and Evolution of Satellite DNA - PMC
Here we describe the different classes of satellite DNA sequences, their satellite-specific chromatin features, and how these features may contribute to satellite DNA biology and …
Genomic Tackling of Human Satellite DNA: Breaking Barriers …
Additionally, the centromeric alpha (α) satellite DNA family was also identified and described, soon becoming the most intensively studied human satDNA sequence. Later on, gamma (γ) …
Evolution of alpha satellite - PubMed
Recent advances in understanding the structure and evolution of human and other primate alpha satellites are summarized in this review. Alpha satellite is one of the most thoroughly studied …
- Author: Huntington F. Willard
- Publish Year: 1991
Higher-order repeat structure in alpha satellite DNA is an attribute …
Aug 15, 2013 · Alpha satellite DNA (AS), a major DNA component of primate centromeres, is composed of a tandem array of repeat units of approximately 170 bp. The AS of hominids …
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Genomic variation within alpha satellite DNA …
Our study demonstrates that genomic variation within highly repetitive, noncoding DNA of human centromere regions has a pronounced impact on genome stability and basic chromosomal function.
Alpha-satellite DNA of primates: old and new families - PubMed
In this report we review alpha-satellite DNA (AS) sequence data to support the following proposed scenario of AS evolution. Centromeric regions of lower primate chromosomes have solely "old" …
Complete genomic and epigenetic maps of human …
In humans, centromeres are defined by alpha satellite DNA (αSat), an AT-rich repeat family composed of ~171 base pair (bp) monomers, which can occur as different subtypes repeated in a head-to-tail orientation for millions of bases …
Review Hierarchical order in chromosome-specific human alpha …
Jan 1, 1987 · In this article, we focus primarily on one family of satellite DNA in the human genome: alpha satellii.e DNA, whose chromo- somal and sequence organization has been the …
A classical revival: Human satellite DNAs enter the genomics era
Aug 1, 2022 · Most human satellite DNA research shifted to alpha satellite DNA once it was determined to be associated with centromere function, while the potential functions of the …
Functional Significance of Satellite DNAs: Insights From
May 4, 2020 · The most abundant satellite family of the human genome is alpha satellite DNA with a monomer unit of about 170 bp, representing more than 50% of the total content of satellite …
Repetitive Fragile Sites: Centromere Satellite DNA as a Source of ...
The novel connection between alpha-satellite DNA instability and human pathological conditions emphasizes the importance of obtaining a truly complete human genome assembly and …
Alpha satellite DNA biology: finding function in the recesses of the ...
Jul 5, 2018 · This review will describe the genomic and epigenetic features of alpha satellite DNA, discuss recent findings of noncoding transcripts produced from distinct alpha satellite arrays, …
(PDF) Satellite DNA: An evolving topic - ResearchGate
Sep 18, 2017 · Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a …
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The most abundant satellite family of the human genome is alpha satellite DNA with a monomer unit of about 170 bp, representing more than 50% of the total content of satellite DNA in …
Dynamic interplay between human alpha-satellite DNA structure …
Nov 3, 2023 · Here, we review evidence of meiotic selection operating to mitigate centromere drive, as well as recent reports on centromere damage, recombination and repair during the …
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Homologous alpha satellite sequences on human acrocentric …
These results indicate the presence of a common subfamily of alpha satellite DNA on the five acrocentric chromosomes and suggest an evolutionary process consistent with recombination …
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