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- Anchorage dependence is a phenomenon exhibited by many normal cells in culture which require attachment to a solid substratum in order to spread and grow12345. Spreading may be necessary in order to absorb rate-limiting growth factors from the culture medium1. The requirement by normal cells to attach to a surface to grow and divide in vitro is a hallmark of malignant transformation and can be induced by oncogenic viruses3.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.anchorage dependence Quick Reference The phenomenon exhibited by many normal cells in culture which require attachment to a solid substratum in order to spread and grow. Spreading may be necessary in order to absorb rate-limiting growth factors from the culture medium.www.oxfordreference.com/display/10.1093/oi/autho…Glossary of biology terms Meaning and definition of anchorage dependence : The requirement that to divide, a cell must be attached to the substratum.www.larapedia.com/glossary_of_biology_terms/an…The requirement by normal cells to attach to a surface to grow and divide in vitro; when cells lose anchorage dependence they no longer respond to external growth controls, which often correlates with tumourigenicity in vivo. It is a hallmark of malignant transformation and can be induced by oncogenic virusesmedical-dictionary.thefreedictionary.com/anchorag…anchorage dependence The necessity for attachment (and spreading) in order that a cell will grow and divide in culture.en_molecular_biology.en-academic.com/391/anch…All rights reserved. anchorage dependence A property of cells that can grow and proliferate only if fixed to a substrate. Many cancer cells do not show anchorage dependence and can be grown in a liquid culture.science-atlas.com/faq/what-is-the-meaning-of-anch…
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Advances in cell culture: anchorage dependence - PMC
WebFeb 2, 2015 · This article provides an overview on critical issues in cell culture of anchorage-dependent cells and provides perspectives for future developments, in particular, with respect to the large-scale amplification of anchorage-dependent stem …
- Author: Otto-Wilhelm Merten
- Publish Year: 2015
See results only from ncbi.nlm.nih.govCell Growth and Protein For…
Miller AO, Menozzi FD, Dubois D. Microbeads and anchorage-dependent …
Three-Dimensional Culture …
Introduction. T issues and organs depend on complex, three-dimensional (3D), …
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MicroHex ®, a polystyrene-based tissue culture microsupport with two …
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Anchorage-dependent cells are of great interest for various biotechnological …
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Anchorage-dependent Cell Cycle Progression. The concept of anchorage …
Anchorage Dependence | Overview & Cells | Study.com
WebNov 21, 2023 · Learn the definition and examples of anchorage dependence and independence in biology. Find out how cells regulate their growth and division, and …
Comprehensive understanding of anchorage-independent …
WebJun 18, 2021 · The following researchers proved the importance of anchorage-independent survival in normal tissue dynamics and cancer progress. Four different forms of …
- Author: Zhong Deng, Huixue Wang, Jinlong Liu, Yuan Deng, Nu Zhang
- DOI: 10.1038/s41419-021-03890-7
- Publish Year: 2021
- Publication: Cell Death Dis. 2021 Jul; 12(7): 629.
- Studies of anchorage dependence definition biology
Comprehensive understanding of anchorage-independent …
WebJun 18, 2021 · Four different forms of anchorage-independent survival, including apoptotic cell death (anoikis), nonapoptotic cell death (including autophagy and entosis), and …
WebAnchorage dependence is the requirement of a surface for cell growth and proliferation. This article reviews the biological properties and cultivation methods of anchorage …
Anchorage-dependent cells - Oxford Reference
WebMay 24, 2024 · Overview. anchorage-dependent cells. Quick Reference. Cells (or in vitro cell cultures) that will grow, survive, or maintain function only when attached to an …
Advances in cell culture: anchorage dependence - PubMed
WebFeb 5, 2015 · Anchorage-dependent cells are of great interest for various biotechnological applications. (i) They represent a formidable production means of …
Anchorage-dependent Cell Cycle Progression - PMC
WebJan 1, 1997 · Anchorage-dependent Cell Cycle Progression. The concept of anchorage-dependent growth and the close relationship between anchorage independence and …
From anchorage dependent proliferation to survival: Lessons
WebApr 17, 2008 · Abstract. Anchorage to extracellular matrix (ECM) is essential for the execution of the mitotic program of nontransformed cells as they need simultaneous …
Anchorage dependence - Oxford Reference
WebAnchorage dependence is the requirement of normal cells in culture to attach to a solid substratum for growth and spreading. Loss of anchorage dependence is a sign of …
Anchorage-dependent Cell Cycle Progression | Journal of Cell …
WebAuthor and Article Information. J Cell Biol (1997) 136 (1): 1–4. https://doi.org/10.1083/jcb.136.1.1. Article history. Standard View. PDF. Share. Tools. The …
Advances in cell culture: Anchorage dependence
WebFeb 5, 2015 · Advances in cell culture: Anchorage dependence. February 2015. Philosophical Transactions B 370 (1661) DOI: 10.1098/rstb.2014.0040. Source. PubMed. Authors: Otto-Wilhelm Merten. Miltenyi...
Loss of anchorage primarily induces non-apoptotic cell death
WebJan 22, 2015 · Anchorage dependence of cellular growth and survival prevents inappropriate cell growth or survival in ectopic environments, and serves as a potential …
Anchorage Independent Growth - an overview | ScienceDirect …
WebAnchorage-independent growth is a hallmark of anoikis resistance and the path to further steps in metastasis. Cell culture models using a semisolid medium to replicate …
Density dependent inhibition of growth - Biology Online
WebJul 24, 2022 · Density dependent inhibition of growth. (Science: cell culture) The phenomenon exhibited by most normal ( anchorage dependent) animal cells in culture …
Integrins, Oncogenes, and Anchorage Independence - PMC
WebNov 11, 1997 · T he ability of cancer cells to proliferate in the absence of adhesion to extracellular matrix (ECM) 1 proteins, termed anchorage independence of growth, correlates closely with tumorigenicity in animal models ( 14 ).
WebFACTS. There are four different forms of anchorage-independent survival, such as anoikis, autophagy, entosis, and cell cycle arrest,reportedintheliterature.
Advances in cell culture: anchorage dependence | Philosophical ...
WebThis article provides an overview on critical issues in cell culture of anchorage-dependent cells and provides perspectives for future developments, in particular, with respect to the …
Anchorage-Independent Cell Growth Assay for Cancer Stem Cells ...
WebMay 26, 2023 · Anchorage-independent growth is a characteristic feature of transformed cells, which means the cells have the ability to grow independently of a solid …
Regulation of anchorage-dependent signal transduction by
WebAug 17, 2000 · Abstract. Activation of the canonical mitogen-activated protein kinase (MAPK) cascade by soluble mitogens is blocked in non-adherent cells. It is also …
Anchorage-independent cell Definition and Examples - Biology …
WebJul 21, 2021 · Definition. noun. A cell that has lost the need for anchorage dependence, which is essential for cell growth, division, and spreading. Supplement. Cell s that …
What Makes a Cancer Cell a Cancer Cell? - Holland …
WebThis attachment is responsible for what was termed “anchorage dependence.” Normal cells that are detached from their binding to the ECM undergo apoptosis, whereas tumor cells that are less dependent on this …
Anchorage-independent cell growth signature identifies tumors …
WebJun 1, 2009 · Among these, the ability to exhibit anchorage-independent cell growth (colony-forming capacity in semisolid media), has been considered to be …
Anchorage Definition and Examples - Biology Online Dictionary
WebFeb 24, 2022 · Anchorage. (Science: cell biology) attachment, not necessarily adhesive in character, because the mechanism is not assumed the term ought to be more widely …
Classification of molds and definition of mold contamination
WebMay 21, 2024 · The term “molds” is defined and relevant sources of molds are given. The conditions and growth of mold fungi are explained. The determination of mould spores and colony-forming units (CFU) in the air is briefly explained and it is made clear that the total spore count is relevant for assessing the sensitizing and allergenic effect of moulds. …
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