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    Wikipedia
    https://en.wikipedia.org/wiki/Barnes_maze

    Barnes maze - Wikipedia

    The Barnes maze is a tool used in psychological laboratory experiments to measure spatial learning and memory. The test was first developed by Dr. Carol Barnes in 1979. The test subjects are usually rodents such as mice or lab rats, which either serve as a control or may have some genetic variable or … See more

    Set-up

    The Barnes maze consists of a circular surface with up to 20 circular holes around its circumference. Visual cues, such as colored shapes or patterns, are placed around the table in plain sight of the animal. The table … See more

    Comparison to other mazes

    The Barnes maze is similar to the Morris water navigation task and to the radial arm maze task, but does not utilize a strong aversive stimulus (stress induced by swimming such as in … See more

    Overview image
    Performance image
    Performance

    Performance is typically measured by number of errors the rodent makes, i.e. the number of times it pokes its nose into a hole that does not contain the escape box. The rate of decline … See more

    See also

    • Morris water navigation task
    • Oasis maze See more

     
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  4. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891830

    Barnes Maze Procedure for Spatial Learning and Memory in Mice

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    An updated Barnes maze protocol for assessing the ... - …
    sciencedirect.com
    Barnes maze - ANY-maze
    any-maze.com
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  5. PubMed
    https://pubmed.ncbi.nlm.nih.gov/29651452

    Barnes Maze Procedure for Spatial Learning and Memory in Mice

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    Barnes Maze | Spatial Memory Test | Animal Studies - San …
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  6. Studies of barnes maze test
    Barnes Maze Procedure for Spatial Learning and Memory in Mice
    The Barnes maze is a dry-land based rodent behavioral paradigm for assessing spatial learning and memory that was originally developed by its namesake, Carol Barnes. It represents a well-established alternative to the more popular Morris Water maze
    Author: Matthew W. Pitts
    Published: 2018/03/03
    Publication: Bio Protoc. 2018 Mar 5; 8(5): e2744.
    National Center for Biotechnology Information · nih.gov
    Barnes Maze Procedure for Spatial Learning and Memory in Mice
    The Barnes maze is a dry-land based rodent behavioral paradigm for assessing spatial learning and memory that was originally developed by its namesake, Carol Barnes. It represents a well-established alternative to the more popular Morris Water maze
    Author: Matthew W Pitts
    Published: 2018/03/05
    Keywords: Behavior; Cognition; Hippocampus; Mouse; Spatial memory
    PubMed · nih.gov
    Barnes maze test for spatial memory: A new, sensitive scoring system for mouse search strategies
    The Barnes maze is a task used to assess spatial learning and memory in rodents. It requires animals to learn the position of a hole that can be used as an escape from a bright and open arena. The often-used parameters of latency and path length to
    Published: 2024/02/26
    Cited By: 0
    Keywords: Spatial learning; Spatial memory; Barnes maze test; Search strategies; Traumatic brain injury; Neurodegenerative disease
    ScienceDirect · sciencedirect.com
    Assessment of spatial learning and memory in the Barnes maze task in rodents—methodological consideration
    There are several well-known animal tasks used for evaluating spatial learning and memory (Paul et al. 2009; Morellini 2013). These tests assume that the animal learns to solve a maze by using positive environmental (food, water, shelter) or negative
    Author: Kinga Gawel, Ewa Gibula, Marta Marszalek-Grabska, Joanna Filarowska, Jolanta H. Kotlinska
    Published: 2019
    Publication: Naunyn Schmiedebergs Arch Pharmacol. 2019; 392(1): 1–18.
    National Center for Biotechnology Information · nih.gov
    Assessment of spatial memory in mice
    The average life expectancy in the United States has dramatically increased due to improved nutrition and health care measures (Harman 1999). The US Census Bureau projects that there will be 72 million people over the age of 65 by 2030 representing 20%
    Author: Sunita Sharma, Sharlene Rakoczy, Holly Brown-Borg
    Published: 2010/10/10
    DOI: 10.1016/j.lfs.2010.09.004
    National Center for Biotechnology Information · nih.gov
    Barnes Maze Test for Spatial Memory: A New, Sensitive Scoring System for Mouse Search Strategies
    The Barnes maze is a task used to assess spatial learning and memory in rodents. It requires animals to learn the position of a hole that can be used as an escape from a bright and open arena. The often-used parameters of latency and path length to
    Author: Peris LR, Scheuber MI, Shan H, Braun M, Schwab ME
    Published: 10/26/2023
    Keywords: Barnes maze test; Neurodegenerative disease; Search strategies; Spatial learning; Spatial memory; Traumatic brain injury
    PubMed · nih.gov
    Barnes maze testing strategies with small and large rodent models
    Spatial learning and memory of laboratory rodents is often assessed via navigational ability in mazes, most popular of which are the water and dry-land (Barnes) mazes. Improved performance over sessions or trials is thought to reflect learning and memory
    Author: Cheryl S Rosenfeld
    Published: 2014/02/26
    Keywords: National Institutes of Health; National Center for Biotechnology Information; National Library of Medicine; MEDLINE;
    PubMed · nih.gov
    Spatial Learning and Memory in Barnes Maze Test and Synaptic Potentiation in Schaffer Collateral-CA1 Synapses of Dorsal Hippocampus in Freely Moving Rats
    Introduction: Synaptic plasticity has been suggested as the primary physiological mechanism underlying memory formation. Many experimental approaches have been used to investigate whether the mechanisms underlying Long-Term Potentiation (LTP) are activated
    Author: Azam Sadeghian, Yaghoub Fathollahi, Mohammad Javan, Amir Shojaei, Nastaran Kosarmadar, Mahmoud Rezaei, Javad Mirnajafi-Zadeh
    Published: Sep-Oct 2019
    Publication: Basic Clin Neurosci. 2019 Sep-Oct; 10(5): 461–468.
    National Center for Biotechnology Information · nih.gov
    Refinement of the Barnes and Morris water maze protocols improves characterization of spatial cognitive deficits in the lithium-pilocarpine rat model of epilepsy
    Temporal lobe epilepsy (TLE) often causes cognitive impairment, especially a decline in spatial memory. Reductions in spatial memory and learning are also common in rodent models of TLE. The Morris water maze and the Barnes maze are the standard methods
    Published: 2023/10/01
    Cited By: 0
    Keywords: Temporal lobe epilepsy; Pilocarpine; Rat; Spatial memory
    ScienceDirect · sciencedirect.com
    Barnes Maze Testing Strategies with Small and Large Rodent Models
    Spatial learning and memory of laboratory rodents is often assessed via navigational ability in mazes, most popular of which are the water and dry-land (Barnes) mazes. Improved performance over sessions or trials is thought to reflect learning and memory
    Author: Cheryl S. Rosenfeld, Sherry A. Ferguson
    Published: 2014
    Publication: J Vis Exp. 2014; (84): 51194.
    National Center for Biotechnology Information · nih.gov
    Intranasal creatine administration increases brain creatine level and improves Barnes maze performance in rats
    While skeletal muscle creatine levels can be enhanced by exogenous creatine supplementation, the elevation of brain creatine levels with oral creatine administration remains a challenge due to a lack of effective transportation of creatine through the
    Published: 2023/09/01
    Cited By: 0
    Keywords: ATP adenosine triphosphate; ADP adenosine diphosphate; GAMT guanidinoacetate methyltransferase; AGAT L-arginine: glycine amidino transferase; BBB blood-brain barrier
    ScienceDirect · sciencedirect.com
    An n-3 Fatty Acid Deficient Diet Affects Mouse Spatial Learning in the Barnes Circular Maze
    Deficiency in n-3 fatty acids has been accomplished through the use of an artificial rearing method in which ICR mouse pups were hand fed a deficient diet starting from the second day of life. There was a 51% loss of total brain DHA in mice with an n-3
    Author: Irina Fedorova, Nahed Hussein, Carmine Di Martino, Toru Moriguchi, Junji Hoshiba, Sharon Majchrzak, Norman Salem, Jr.
    Published: 2007
    DOI: 10.1016/j.plefa.2007.10.013
    National Center for Biotechnology Information · nih.gov
  7. ScienceDirect
    https://www.sciencedirect.com/topics/neuroscience/barnes-maze

    Barnes Maze - an overview | ScienceDirect Topics

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    Spatial Memory
    Modified Barnes Maze Test
    5xfad Barnes Maze
  8. ScienceDirect
    https://www.sciencedirect.com/science/article/pii/S0166432823004485

    Barnes maze test for spatial memory: A new, sensitive scoring …

    Tags:
    Spatial Memory
    Mice Memory
    Barnes Maze Mice
  9. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311199

    Assessment of spatial learning and memory in the Barnes maze …

    Tags:
    Spatial Memory
    Morris Water Maze
    Barnes Maze
    Publish Year:2019
  10. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457258

    Assessment of spatial memory in mice - PMC - National Center …

    Tags:
    Spatial Memory
    Mice Memory
    Morris Water Maze
    Barnes Maze
  11. Bio-protocol
    https://bio-protocol.org/pdf/bio-protocol2744.pdf
    [PDF]

    Barnes Maze Procedure for Spatial Learning and Memory in …

    Tags:
    Spatial Memory
    Mice Memory
    Morris Water Maze
    Barnes Maze Mice
  12. Protocol Exchange on Research Square
    https://protocolexchange.researchsquare.com/article/nprot-349/v1

    Barnes maze, a useful task to assess spatial reference memory …

    Tags:
    Spatial Memory
    Carol A. Barnes
    Publish Year:2007
    Barnes Maze Analysis
  13. PubMed
    https://pubmed.ncbi.nlm.nih.gov/37898351

    Barnes maze test for spatial memory: A new, sensitive scoring …

    Tags:
    Spatial Memory
    Barnes Maze Latency
  14. conductscience.com
    https://maze.conductscience.com/mazes-basics-barnes-maze-test

    The Barnes Maze Test | Maze Engineers

  15. Oxford Academic
    https://academic.oup.com/bioinformatics/article/32/21/3314/2415073

    Unbiased classification of spatial strategies in the Barnes maze

    Tags:
    Morris Water Maze
    Barnes Maze Latency
    Machine Learning
  16. PubMed
    https://pubmed.ncbi.nlm.nih.gov/24637673

    Barnes maze testing strategies with small and large rodent models

    Tags:
    Spatial Memory
    Barnes Maze Testing Strategies
    Publish Year:2014
  17. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149949

    Spatial Learning and Memory in Barnes Maze Test and Synaptic ...

    Tags:
    Spatial Memory
    Barnes Maze
    Publish Year:2019
    10.32598/bcn.9.10.330
  18. Scantox
    https://scantox.com/.../barnes-maze-test

    Barnes Maze Test - Scantox | CRO

    Tags:
    Spatial Memory
    Mice Memory
    Morris Water Maze
    Barnes Maze Mice
  19. conductscience.com
    https://maze.conductscience.com/portfolio/barnes-maze

    Barnes Maze - Maze Engineers

    Tags:
    Spatial Memory
    Mice Memory
    Barnes Maze Mice
    Carol A. Barnes
  20. ScienceDirect
    https://www.sciencedirect.com/science/article/pii/S1525505023003104

    Refinement of the Barnes and Morris water maze protocols …

    Tags:
    Morris Water Maze
    Barnes Maze
  21. Springer
    https://link.springer.com/article/10.1007/s00210-018-1589-y

    Assessment of spatial learning and memory in the Barnes maze …

    Tags:
    Spatial Memory
    Morris Water Maze
    Barnes Maze
    Publish Year:2019
  22. APA PsycNet
    https://psycnet.apa.org/record/2024-31849-001

    Barnes maze test for spatial memory: A new, sensitive scoring …

    Tags:
    Spatial Memory
    Barnes Maze Latency
  23. ResearchGate
    https://www.researchgate.net/figure/Barnes-maze...

    Barnes maze spatial learning and memory retention test. (A) …

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    Spatial Memory
    Barnes Maze
  24. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140524

    Barnes Maze Testing Strategies with Small and Large Rodent …

    Tags:
    Barnes Maze Testing Strategies
    Modified Barnes Maze Test
    5xfad Barnes Maze
  25. Journal of Neuroinflammation
    https://jneuroinflammation.biomedcentral.com/...

    Inhibition of ANGPTL8 protects against diabetes-associated …

  26. ScienceDirect
    https://www.sciencedirect.com/science/article/pii/S0361923023001284

    Intranasal creatine administration increases brain creatine level …

    Tags:
    Spatial Memory
    Barnes Maze
  27. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194649

    An n-3 Fatty Acid Deficient Diet Affects Mouse Spatial Learning in …

    Tags:
    Spatial Memory
    Mice Memory
    Barnes Maze Mice
    Publish Year:2007