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CellChat for systematic analysis of cell–cell communication
Sep 16, 2024 · CellChat is a software package for systematic inference, quantitative analysis and intuitive visualization of cell–cell communication in an easily interpretable way from single-cell...
See results only from nature.comDeciphering cell–cell interac…
Cell–cell interactions orchestrate organismal development, homeostasis …
The diversification of metho…
Transcriptomics provides rich information to infer cell–cell interactions and …
Comparative analysis of cell…
We use multiple published atlas-scale datasets, genetic perturbation screens …
Inference and analysis of cel…
We construct a database of interactions among ligands, receptors and their …
Strategies for monitoring cell…
Here, we summarize technologies at the interface of chemistry and biology that …
Deciphering cell–cell interactions and communication from gene ...
Nov 9, 2020 · Cell–cell interactions orchestrate organismal development, homeostasis and single-cell functions. When cells do not properly interact or improperly decode molecular messages, …
- Author: Erick Armingol, Adam Officer, Olivier Harismendy, Nathan E Lewis
- Publish Year: 2021
Evaluation of cell-cell interaction methods by integrating single …
Oct 17, 2022 · We benchmark 16 cell-cell interaction methods by integrating scRNA-seq with ST data. We characterize cell-cell interactions into short-range and long-range interactions using …
- Studies of cell interaction analysis
The diversification of methods for studying cell–cell interactions …
Jan 18, 2024 · Transcriptomics provides rich information to infer cell–cell interactions and communication, thus accelerating the discovery of the roles of cells within their communities. …
Cell type-specific Interaction Analysis using Doublets in scRNA …
Feb 13, 2023 · Here, we present Cell type-specific Interaction Analysis using Doublets in scRNA-seq (CIcADA), a method for discerning biologically relevant doublets and quantifying their …
scConnect: a method for exploratory analysis of cell–cell …
May 11, 2021 · We propose a method to predict the putative ligand–receptor interactions between cell types from single-cell RNA-sequencing data. This is achieved by inferring and …
Cell2Cell: Explorative Cell Interaction Analysis in Multi-Volumetric ...
Sep 10, 2024 · By analyzing cellular interactions, biomedical experts can gain a more accurate understanding of the intricate relationships between cancer and immune cells. Recent …
- People also ask
Profiling signaling mediators for cell-cell interactions …
Microfluidics-driven single-cell interaction analysis tools aspire to establish a secluded environment for two or more isolated cells, fostering single-cell level measurements of intercellular interactions.
Inference and analysis of cell-cell communication using CellChat
Feb 17, 2021 · We construct a database of interactions among ligands, receptors and their cofactors that accurately represent known heteromeric molecular complexes. We then develop …
Deciphering cell-cell interactions and communication from gene ...
In this Review, we highlight discoveries enabled by analyses of cell-cell interactions from transcriptomic data and review the methods and tools used in this context. Cell-cell …
The promising application of cell-cell interaction analysis in cancer ...
Oct 1, 2023 · Cell-cell interactions instruct cell fate and function. These interactions are hijacked to promote cancer development. Single-cell transcriptomics and spatial transcriptomics have …
A Comparison of Cell-Cell Interaction Prediction Tools Based on …
Computational prediction of cell-cell interactions (CCIs) is becoming increasingly important for understanding disease development and progression. We present a benchmark study of …
Comparative analysis of cell–cell communication at single-cell ...
May 11, 2023 · We use multiple published atlas-scale datasets, genetic perturbation screens and direct experimental validation to show that Scriabin accurately recovers expected cell–cell …
Comprehensive visualization of cell–cell interactions in single-cell ...
Dec 2, 2022 · Recent years have seen the release of several toolsets that reveal cell–cell interactions from single-cell data. However, all existing approaches leverage mean celltype …
Ligand-Receptor Interactions for Cell-Cell Communication …
Oct 15, 2024 · Cell-cell communication is a frequently used analysis approach in single cell RNA and spatial transcriptomics, and many tools like CellPhoneDB, CellChat and stLearn have …
Pairwise Cell Interaction Analysis | Notion
Cell interactions refers to the physical contact of cells in a 2D space. In Enable Medicine insight reports, we typically use this term to refer to pairwise contact analysis—analyzing whether …
Batch correcting single-cell spatial transcriptomics count data with ...
Feb 25, 2025 · Spatial transcriptomics facilitates gene expression analysis of cells in their spatial anatomical context. Batch effects hinder visualization of gene spatial patterns across samples. …
Single-cell transcriptomic analysis reveals CD8 + T cell …
4 days ago · We identified CD8 + T cell subsets in the CESC microenvironment, revealing significant interactions between CD8 + T cells and other cell types through intercellular …
Cell2Cell: Explorative Cell Interaction Analysis in Multi-Volumetric ...
Sep 10, 2024 · By analyzing cellular interactions, biomedical experts can gain a more accurate understanding of the intricate relationships between cancer and immune cells. Recent …
Inference and analysis of cell-cell communication using CellChat
Feb 17, 2021 · We construct a database of interactions among ligands, receptors and their cofactors that accurately represent known heteromeric molecular complexes. We then develop …
Examining Interactions of Animal Cells with ... - ScienceDirect
6 days ago · To assess chloroplast–cell interactions, up to 10 μl of chloroplast isolation buffer containing 2 to 5 × 10 6 chloroplasts ... >0.05 was considered not significant (ns). For …
Evaluation of cell-cell interaction methods by integrating single …
Oct 17, 2022 · Our study presents a comprehensive evaluation of cell-cell interaction tools for scRNA-seq. CellChat, CellPhoneDB, NicheNet, and ICELLNET show overall better …
Luminescent sensing of conformational integrin activation in living …
Feb 17, 2025 · Villari et al. present the generation of a luminescent reporter for a β1 integrin activation sensor (β1IAS). A siRNA HTS on β1IAS KI endothelial cells revealed previously …
An examination of the LPS-TLR4 immune response through the …
4 days ago · The LPS-TLR4 immune response is a critical mechanism in the body's defense against Gram-negative bacterial infections, yet its dysregulation can lead to severe …
Strategies for monitoring cell–cell interactions - Nature
May 25, 2021 · Here, we summarize technologies at the interface of chemistry and biology that visualize, map or functionally exploit physically interacting cells through microscopy, chemical …
Comparative analysis of the inflammatory response of human …
5 days ago · Analysis of the data showed that NeoSEALER Flo was cytotoxic in a concentration-dependent manner to HGFs, though it appeared marginally more toxic than CeraSeal when …
Cas12a-knock-in mice for multiplexed genome editing, disease
2 days ago · LIVE/DEAD Fixable Near-IR Dead Cell Stain (Invitrogen) was included in surface stains to exclude dead cells from analysis. B cell lineage markers include anti-CD19 BV421; …
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