chuan wu nature medicine - Search
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  1. Nature
    https://www.nature.com/articles/s41591-022-01799-y

    A T cell resilience model associated with response to ... - Nature

    • Despite breakthroughs in cancer immunotherapy, most tumor-reactive T cells cannot persist in solid tumors due to an immunosuppressive environment. We developed Tres (tumor-resilient T cell, https://resi… See more

    Main

    Cancer immunotherapies that act through T cells have led to significant successes. Immune … See more

    Nature
    Results

    Quantification of immunosuppression on CD8+ T cells
    Tres uses two stages to identify gene markers of CD8+ T cells that are resilient to immunosup… See more

    Nature
    Discussion

    We developed a Tres model to identify transcriptomic signatures of T cells that are resilient to immunosuppressive signals in solid tumors. The Tres signature can reliably pre… See more

    Nature
    Methods

    Processing of single-cell RNA-seq data
    For all single-cell datasets, we standardized the transcriptomic levels to log2(TPM / 10 + 1). To train Tres signatures, we normalized the express… See more

    Nature
    Data availability

    The RNA-seq data generated by this study have been deposited to the NCBI Gene Expression Omnibus with accession ID GSE186428. All flow analysis raw data are available i… See more

    Nature
    Code availability

    The interactive Tres server is available at https://resilience.ccr.cancer.gov. The source code and test data for the Tres model and T cell efficacy prediction are available a… See more

    Nature
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  1. Bokep

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  2. Google Scholar
    https://scholar.google.com/citations?user=sZQPVnUAAAAJ

    ‪Chuan Wu‬ - ‪Google Scholar‬

     
  3. Nature
    https://www.nature.com/articles/s41596-024-01061-4

    Rapid parallel reconstruction and specificity screening of ... - Nature

  4. Nature
    https://www.nature.com/articles/s41591-022-01997-8

    Publisher Correction: A T cell resilience model associated

  5. ResearchGate
    https://www.researchgate.net/profile/Chuan-Wu-2

    Chuan WU | Principal Investigator | MD, PhD - ResearchGate

  6. NIH Intramural Research Program
    https://irp.nih.gov/pi/chuan-wu

    Chuan Wu, M.D., Ph.D. - NIH Intramural Research Program

  7. LinkedIn
    https://www.linkedin.com/in/chuan-wu-85175932

    Chuan Wu - National Cancer Institute (NCI) - LinkedIn

  8. Center for Cancer Research
    https://ccr.cancer.gov/staff-directory/chuan-wu

    Chuan Wu, M.D., Ph.D. | Center for Cancer Research

  9. Semantic Scholar
    https://www.semanticscholar.org/author/Chuan-Wu/2157348648

    Chuan Wu - Semantic Scholar

  10. Nature
    https://www.nature.com/articles/nm.1957

    Endothelial basement membrane laminin α5 selectively inhibits

  11. Semantic Scholar
    https://www.semanticscholar.org/author/Chuan-Jin-Wu/120930939

    Chuan-Jin Wu - Semantic Scholar

  12. 香港中文大学（深圳）医学院
    https://med.cuhk.edu.cn/en/event/1146

    Distinguished MED Research Seminar: Prof. WU Chuan

  13. Nature
    https://www.nature.com/articles/srep27695

    Luteolin inhibits GABA A receptors in HEK cells and brain slices

  14. Google Scholar
    https://scholar.google.com/citations?user=QLFhXgMAAAAJ

    ‪Chuan Wang‬ - ‪Google Scholar‬

  15. Me & Qi
    https://www.meandqi.com/herb-database/prepared-sichuan-aconite

    Zhi Chuan Wu (Prepared Sichuan aconite) in Chinese Medicine

  16. Semantic Scholar
    https://www.semanticscholar.org/author/Chuan-Wu/2326083669

    Chuan Wu - Semantic Scholar

  17. Washington University in St.Louis
    https://bulletin.wustl.edu/medicine/departments/radiology

    Department of Radiology - Washington University in St. Louis

  18. Nature
    https://www.nature.com/articles/nature11981

    Dynamic regulatory network controlling TH17 cell ... - Nature

  19. foci-tech.com
    http://foci-tech.com/dr-xinsheng-jiang

    Dr. Xinsheng Jiang - Foci-tech

  20. Nature
    https://www.nature.com/articles/s41591-021-01381-y

    Health systems resilience in managing the COVID-19 ... - Nature

  21. Nature
    https://www.nature.com/articles/s41591-018-0196-2

    Wireless bioresorbable electronic system enables sustained

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