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- Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Hyperkeratosis causes patches of thick, rough skin. There are many types of this condition, including corns and calluses, warts, eczema and psoriasis. Causes include allergies, autoimmune diseases, medications and sun exposure.my.clevelandclinic.org/health/diseases/hyperkerato…"Uneven skin texture is commonly a result of excess dead skin cells that build up on the surface of the skin. This can make areas of the skin feel rough or bumpy to the touch and can also give the skin a dull appearance," explains board-certified cosmetic dermatologist Paul Jarrod Frank, MD.www.byrdie.com/how-to-fix-uneven-skin-texture-46…
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