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- DNA virus
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Cytomegalovirus - StatPearls - NCBI Bookshelf
WEBAug 8, 2023 · While CMV encodes for functional DNA polymerase, the virus makes use of the host RNA polymerase for the transcription of its …
- Affiliations: Cleveland Clinic Foundation
- Published: 2023/08/08
Cytomegalovirus - Wikipedia
WEBHerpesviruses have some of the largest genomes among human viruses, often encoding hundreds of proteins. For instance, the double‑stranded DNA (dsDNA) genome of wild …
- Also known as: CMVContent medically reviewed by
Dr. Rakshith Bharadwaj
MD, Internal MedicineView full profile on
LinkedInA common viral infection that is mostly harmless, and only rarely causes illness. This causes body pain, fever, tiredness and sorethroat.
Urgent medical attention is usually recommended in severe cases by healthcare providers
Certain types can be dangerous or life threatening
Common (More than 200,000 cases per year in US)
Treatable by a medical professional
Often requires lab test or imaging
Can last several days or weeks
Transmitted through direct contactSource: Focus Medica . For informational purposes only. Consult a medical professional for advice. Learn more
Approach to the diagnosis of cytomegalovirus infection
WEBThe diagnosis and monitoring of CMV infection and tissue-invasive disease will be discussed here, with an emphasis on the role of diagnostic tests and their strengths and …
Interpreting Quantitative Cytomegalovirus DNA Testing: …
WEBCMV DNA viral load testing is an important aid for assessing risk of disease, diagnosing disease, and monitoring response to therapy. The interpretation of CMV DNA viral load …
Diagnosis of Cytomegalovirus Infections - PMC - National Center …
WEBDetection of cytomegalovirus (CMV) DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the …
Cytomegalovirus | Microbiology Spectrum - American Society for …
WEBDetection of cytomegalovirus (CMV) DNA by polymerase chain reaction is associated with hearing loss in newborns with symptomatic congenital CMV infection involving the …
Cytomegalovirus (CMV) - Medscape
WEBWhen the host is infected, CMV DNA can be detected with polymerase chain reaction (PCR) in all the different cell lineages and organ systems in the body. Upon initial infection, CMV infects the...
Functional single-cell genomics of human cytomegalovirus …
WEBHere we define the functional contribution of each viral and host factor involved in human cytomegalovirus infection in primary human fibroblasts through pooled CRISPR …
Structure of human cytomegalovirus virion reveals host tRNA …
WEBUnder the Baltimore nucleic acid-based virus classification scheme, the herpesvirus human cytomegalovirus (HCMV) is a Class I virus, meaning that it contains a double-stranded …
Diagnosis of cytomegalovirus infection from clinical whole …
WEBRapid whole genome sequencing (rWGS) of peripheral blood has been used to detect microbial DNA in acute infections. Cytomegalovirus (CMV) is a herpesvirus capable of …
Human cytomegalovirus: clinical aspects, immune …
WEBComparison of the CMV brite turbo assay and the digene hybrid capture CMV DNA (Version 2.0) assay for quantitation of cytomegalovirus in renal transplant recipients.
Human Cytomegalovirus (HCMV) | British Society for Immunology
WEBHuman cytomegalovirus (HCMV) is a beta-herpesvirus that causes lifelong infection in humans. HCMV has a prevalence of 55-100% within the human population, depending …
Cytomegalovirus: pathogen, paradigm, and puzzle - PMC
WEBHuman cytomegalovirus (CMV), one of the eight herpesviruses that commonly infect humans, is best known for its propensity to cause disease in immunocompromised …
Cytomegalovirus: Video, Anatomy, Definition & Function | Osmosis
WEBCytomegalovirus (CMV), also known as human herpes 5, is a double-stranded DNA virus. It is usually asymptomatic in immunocompetent individuals, but can present with severe …
Characterizing cytomegalovirus infection one cell at a time
WEBHCMV has the largest known genome of human herpesviruses, with more than 235 kbp of double-stranded DNA (dsDNA). In addition, HCMV has alternative transcript start sites, …
Clinical Overview of CMV and Congenital CMV
WEBKey points. For most people, cytomegalovirus (CMV) infection is not a serious health problem. Diagnose, treat, and monitor children with congenital CMV to help improve …
Interpreting Quantitative Cytomegalovirus DNA Testing: …
WEBCMV DNA viral load testing is an important aid for assessing risk of disease, diagnosing disease, and monitoring response to therapy. The interpretation of CMV DNA viral load …
Human cytomegalovirus long noncoding RNA4.9 regulates viral …
WEBRNA4.9 is transcribed from the HCMV origin of replication ( oriLyt) and forms an RNA-DNA hybrid (R-loop) through its G+C-rich 5’ end, which may be important for the initiation of …
WEBHuman cytomegalovirus (HCMV) causes life-threatening WBC by two molecular hybridization assays (dot blot and infection in immunocompromised persons, particularly …
Molecular characterization of human cytomegalovirus infection …
WEBAbstract. Human cytomegalovirus (HCMV) can result in either productive or non-productive infection, with the latter potentially leading to viral latency. The molecular …
The Wide Spectrum of Presentations of Cytomegalovirus …
WEBCMV is a ubiquitous DNA virus that establishes infection and results in 40–100% seropositivity. Viral replication occurs following an acquired primary infection (or …
Clinical Utility of Viral Load in Management of Cytomegalovirus ...
WEBAbstract. SUMMARY. The negative impact of cytomegalovirus (CMV) infection on transplant outcomes warrants efforts toward improving its prevention, diagnosis, and …
Human cytomegalovirus – no longer just a DNA virus - Nature
WEBHuman cytomegalovirus (HCMV) is classified as a DNA herpesvirus. A recent study showed that the HCMV virion contains not only DNA, but also four species of mRNA, …
Circular RNA ACVR2A promotes the progression of …
WEBCircular RNA (circRNA) is thought to mediate the occurrence and development of human cancer and usually acts as a tiny RNA (miRNA) sponge to regulate downstream gene …
Quantitation of Cytomegalovirus: Methodologic Aspects and …
WEBThis review discusses methodological aspects of currently used quantitative assays for CMV (i.e., viral culture techniques, antigen detection assays, DNA detection assays …
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