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Appreciating the mechanics of biopolymer networks is key to understanding the mechanics of cells. Here, we review the mechanical properties of cytoskeletal polymers and discuss the …

In general, the mechanical properties are defined by the cytoskeleton and the volume of the cell. The rigidity of the cytoskeleton is reinforced by the membrane which maintains constant cell …

1 day ago · Signalling-induced changes to the actomyosin cytoskeleton and cell–cell adhesion establish and maintain cellular ... K. & Pelling, A. E. Investigating cell mechanics with atomic …

Jan 1, 2010 · This review summarizes selected aspects of current work on cell mechanics with an emphasis on the structures that are activated in cell-cell contacts, that regulate ion flow across …

Moreover, cytoskeleton-binding proteins (CBPs) orchestrate these functions by interacting with cytoskeletal components to form a complex system key to generating cellular biochemical …

Appreciating the mechanics of biopolymer networks is key to under-standing the mechanics of cells. Here, we review the mechanical properties of cytoskeletal polymers and discuss the …

The cytoskeleton carries out three broad functions: it spatially organizes the contents of the cell; it connects the cell physically and biochemically to the external environment; and it generates …

Jan 1, 2020 · In this paper, we therefore aim to provide informative description of the cell membrane and cytoskeleton mechanics, followed by unique computational modeling efforts to …

Biomechanics plays an important role in cell metabolism, regulation of mechanotransduction pathways and also modulation of nuclear response. The mechanical properties of the cell are …

Nov 1, 2017 · Appreciating the mechanics of biopolymer networks is key to understanding the mechanics of cells. Here, we review the mechanical properties of cytoskeletal polymers and …

May 6, 2020 · Our new approach for assessing cell mechanics has linked behaviors seen in 2D cultures to a 3D matrix, and connected remodeling of the cytoskeleton to homeostatic …

Jan 8, 2024 · Here, we develop a data-driven modeling pipeline to learn the mechanical behavior of adherent cells. We first train neural networks to predict cellular forces from images of …

1 day ago · In this context, apical-basal polarity is not only essential to fulfill the cell’s diverse functions but also necessary for the localization of the adhesion molecules that interconnect …

Jan 21, 2009 · We investigated the electrocoupling mechanisms of cellular biomechanics modulation by an electrical stimulation in two mechanically distinct cell types—human …

The cytoskeleton is an intricate and dynamic fibrous network that has an essential role in the generation and regulation of cell architecture and cellular mechanical properties.

Jan 1, 2010 · Cells are highly complex structures with unique physiology and biomechanical properties. A multiscale multiphysics methodology is required to properly understand the …

Apr 19, 2021 · External forces, sensed through the cytoskeleton or distortion of the cell and organelles, induce metabolic changes in the cell. The resulting changes in metabolism, in turn, …

We investigated the electrocoupling mechanisms of cellular biomechanics modulation by an electrical stimulation in two mechanically distinct cell types—human mesenchymal stem cells …

5 days ago · The cytoskeleton is a comprehensive and dynamic system that serves as the structural framework of the cell, enabling it to maintain its morphology under external …