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  2. Taking estrogen can lead to several health risks, including12:
    • Increased risk of endometrial cancer (only if you still have your uterus and are not taking a progestin along with estrogen)
    • Increased risk of blood clots and stroke
    • Increased chance of gallbladder/gallstone problems
    • Increased risk of dementia if hormone therapy is started after midlife
    • Increased risk of certain cancers, specifically breast cancer
    • Birth irregularities, which can cause premature pregnancy termination
    • Dense breast tissue
    Learn more:
    Known health risks include: An increased risk of endometrial cancer (only if you still have your uterus and are not taking a progestin along with estrogen). Increased risk of blood clots and stroke. Increased chance of gallbladder/gallstone problems. Increased risk of dementia if hormone therapy is started after midlife.
    my.clevelandclinic.org/health/treatments/15245-hor…

    The risk factors and side effects associated with estrogen use include:

    • Blood clots. Estrogen increases your risk of blood clots, which can cause a stroke, a heart attack, and even death.
    www.healthline.com/health/womens-health/benefit…
     
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