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- Taking estrogen can lead to several health risks, including12:
- Increased risk of endometrial cancer (only if you still have your uterus and are not taking a progestin along with estrogen)
- Increased risk of blood clots and stroke
- Increased chance of gallbladder/gallstone problems
- Increased risk of dementia if hormone therapy is started after midlife
- Increased risk of certain cancers, specifically breast cancer
- Birth irregularities, which can cause premature pregnancy termination
- Dense breast tissue
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Known health risks include: An increased risk of endometrial cancer (only if you still have your uterus and are not taking a progestin along with estrogen). Increased risk of blood clots and stroke. Increased chance of gallbladder/gallstone problems. Increased risk of dementia if hormone therapy is started after midlife.my.clevelandclinic.org/health/treatments/15245-hor…The risk factors and side effects associated with estrogen use include:
- Blood clots. Estrogen increases your risk of blood clots, which can cause a stroke, a heart attack, and even death.
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