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  1. Dictionary
    an·tag·o·nize
    [anˈtaɡəˌnīz]
    verb
    antagonize (verb) · antagonizes (third person present) · antagonized (past tense) · antagonized (past participle) · antagonizing (present participle) · antagonise (verb) · antagonises (third person present) · antagonised (past tense) · antagonised (past participle) · antagonising (present participle)
    1. cause (someone) to become hostile or angry:
      "he antagonized fellow architects by criticizing traditional values" · "she seemed reckless in the way she deliberately tried to antagonize her interviewers"
    2. biochemistry
      (of a substance) act as an antagonist of (a substance or its action):
      "two other drugs antagonized the antidepressant-like effect"
    Origin
    mid 17th century (in the sense ‘compete with’): from Greek antagōnizesthai, from ant- ‘against’ + agōnizesthai ‘struggle’ (see agonize).
    Translate antagonize to
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    Similar and Opposite Words
    verb
    1. cause (someone) to become hostile or angry:
      Opposite:
     
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  2. Antagonize Definition & Meaning - Merriam-Webster

     
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  8. ANTAGONIZE definition and meaning | Collins …

    If you antagonize someone, you make them feel hostile towards you. She didn't want to antagonize him further. 2 meanings: 1. to make hostile; annoy or irritate 2. to act in opposition to or counteract.... Click for more definitions.

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