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    break·through
    [ˈbrākˌTHro͞o]
    noun
    breakthrough (noun) · breakthroughs (plural noun) · break-through (noun) · break-throughs (plural noun)
    1. a sudden, dramatic, and important discovery or development:
      "a major breakthrough in DNA research"
      • an instance of achieving success in a particular sphere or activity:
        "her big breakthrough came on the stage when she won a Tony Award in 1958" · "the band's breakthrough album"
    2. denoting a symptomatic case of a disease occurring despite preventative medication, vaccination, or prior infection:
      "we're seeing more and more of these breakthrough infections"
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  3. an important discovery or event that helps to improve a situation or provide an answer to a problem: Scientists are hoping for a breakthrough in the search for a cure for cancer. A major breakthrough in negotiations has been achieved.
    dictionary.cambridge.org/dictionary/english/breakth…
    a : a sudden advance especially in knowledge or technique a medical breakthrough b : a person's first notable success often used before another noun
    www.merriam-webster.com/dictionary/breakthrough
    any significant or sudden advance, development, achievement, or increase, as in scientific knowledge or diplomacy, that removes a barrier to progress: The jet engine was a major breakthrough in air transport.
    www.dictionary.com/browse/breakthrough
    BREAKTHROUGH meaning: 1 : a sudden increase in knowledge, understanding, etc. an important discovery that happens after trying for a long time to understand or explain something sometimes used before another noun; 2 : a person's first important success sometimes used before another noun
    www.britannica.com/dictionary/breakthrough
     
  4. Breakthrough Definition & Meaning - Merriam-Webster

     
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