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- 1 mg to 2 mg dailyEstradiol is a lab-made form of estrogen that’s most often prescribed for menopausal symptoms and low estrogen levels. The recommended oral estradiol dose for menopause symptoms is 1 mg to 2 mg daily, on a 21-day on, 7-day off cycle. Estradiol tablets are also taken off-label as part of estrogen-based gender-affirming hormone therapy (GAHT).www.goodrx.com/estradiol/dosage
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