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- Studies of evaluation of cytotoxicity liposomes
Immunological and Toxicological Considerations for the Design of …
Jan 22, 2020 · Papahadjopoulos et al. first reported the cytotoxicity of liposomes in healthy mouse fibroblast L929 cells in 1973. They discovered that incorporation of 3% or 10% of lysophosphatidylcholine (lysolecithin, lysoPC) into liposomes increases cellular uptake (i.e., …
- Author: Collin T Inglut, Aaron J Sorrin, Thilinie Kuruppu, Shruti Vig, Julia Cicalo, Haroon Ahmad, Huang-Chi...
- Publish Year: 2020
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The first dose of pegylated liposomes stimulates the production of anti-PEG …
Doxil
Concomitant administration of chemo- and radiation therapy may enhance the …
Ethylene Glycol
1 Introduction. When foreign materials are implanted into a wound space, the …
Toxicity screening
This paper describes some simple in vitro cellular tests for direct toxicity of …
Preparation, characterization and in vitro cytotoxicity evaluation of ...
Nov 1, 2022 · Though it has been proven that liposomes improved the biocompatibility of many encapsulated antibiotics, no research has been conducted to evaluate the cytotoxicity profile …
Development of lipid nanoparticles and liposomes reference …
Oct 27, 2022 · The main objective of this study was to evaluate toxicity of six lipid based formulations with three surface charges—anionic, neutral or cationic, to establish certified …
Optimization, characterization, and cytotoxicity studies of novel …
Jan 4, 2024 · This study focused on enhancing the solubility, evaluation of the cytotoxicity, and investigation of the antimycobacterial activity of the compound I through encapsulation in …
PEGylated liposomes enhance the effect of cytotoxic drug: A review
Feb 17, 2023 · In vitro, composite liposomes show significant cytotoxicity against drug-resistant MCF-7/Adr tumor cells, and they improve drug bioavailability and tumor retention in vivo . …
Synthesis, Characterization, and Acute Cytotoxicity …
Jan 13, 2023 · Using RAW264.7 murine macrophages as model immune cells, cell culture experiments revealed an improved acute cytotoxicity profile of chloroquine encapsulating liposomes with >90% cell viability compared to free …
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Evaluation of novel cationic gene based liposomes …
Oct 22, 2019 · This study has investigated the encapsulation and transfection efficiency of cationic liposomes prepared from DOTAP and carboxymethyl-β-cyclodextrin (CD).
Identification and Evaluation of Cytotoxicity of Peptide Liposome ...
Feb 22, 2018 · Our results demonstrated that the cytotoxicity of citron liposome was dependent on cell type in high concentrations (1 and 5 mg/mL), selectively against primary human cardiac …
Preparation and in vitro evaluation of PEGylated liposomes as …
Jan 14, 2021 · The used method for in vitro cytotoxicity evaluation, which is based on the mechanism of counting alive cells after incubation with the pre-determined agents, is …
Evaluation of Cytotoxicity and Metabolic Profiling of
Jul 31, 2024 · Evaluation of Cytotoxicity and Metabolic Profiling of Synechocystis sp. Extract Encapsulated in Nano-Liposomes and Nano-Niosomes Using LC-MS, Complemented by …
Evaluation of acute toxicity and in vitro antitumor activity of a …
Sep 1, 2023 · Fol-coated pH-sensitive liposomes enhance cytotoxicity against breast cancer cells. •. Fol-coated liposomes reduce cell migration and potentially reduce metastasis. •. Fol-coated …
Cytotoxicity evaluation of curcumin-loaded affibody-decorated …
Cytotoxic activity of curcumin was improved by its encapsulation in both liposomes and affibody-decorated liposomes. The Annexin V staining indicated the induction of apoptosis by affibody …
Development and evaluation of high permeability liposomes for …
May 1, 2024 · The cell viability and animal safety tests confirmed the good biosafety of TMFP-Liposome E. Overall, this research suggests that TMFP may serve as a potential therapeutic …
In vitro evaluation of chitosan‐coated liposome containing both ...
Jul 19, 2017 · This study aims to evaluate the cytotoxicity, antioxidant activity and antimicrobial activity of CCAL. Methods. This article evaluated the in vitro cytotoxicity and antioxidant …
Liposomal formulations of cytotoxic drugs - PubMed
Liposomes are microscopic particles of lipid bilayer membrane that enclose aqueous internal compartments. These drug-delivery systems offer a very interesting opportunity for delivering …
Preparation and in vitro evaluation of BBG-250 loaded liposomal ...
Feb 12, 2024 · The cytotoxicity of HSPC and pH-sensitive liposomes was assessed through an MTT assay on A549 cell lines. The results revealed that both liposomal formulations exhibited …
The Potential of Optimized Liposomes in Enhancement of …
Dec 17, 2021 · In summary, we demonstrated the encapsulation of propolis into liposomes for enhancing its cytotoxic effect against the squamous cell carcinoma cell line (Hep-2) of head …
Evaluation of Cytotoxicity and Metabolic Profiling of
Jul 31, 2024 · The results showed the potential activities of the prepared N1, N2, L1, and L2 against the three cell lines, where L1 had cytotoxicity IC50 values of 19.56, 33.52, and 9.24 …
Development of a novel cationic liposome: Evaluation of liposome ...
Jun 1, 2018 · The cytotoxicity of CL/miR-101 was approximately 12% more than the bare miRNA-101 in KG-1 cells and comparatively less significant amount of cytotoxicity was seen in HBMF …
Preparation and cytotoxicity of cisplatin-containing liposomes
We encapsulated cisplatin into stealth pH-sensitive liposomes and studied their stability, cytotoxicity and accumulation in a human small-cell lung carcinoma cell line (GLC4) and its …
Optimization, characterization, and cytotoxicity studies of novel …
Jan 4, 2024 · Optimization, characterization, and cytotoxicity studies of novel anti-tubercular agent-loaded liposomal vesicles. Manar M. Obiedallah, 1 Maxim A. Mironov, 2 Danila V. …
Antimicrobial and antibiotic-potentiating effect of calcium peroxide ...
2 days ago · As expected, concentration dependent cytotoxicity was observed with a lethal concentration 50% of 16 µg/mL (Supplementary Fig. 1a). The concentration of CaO 2 NP for …
Toxicity screening of liposomes - PubMed
This paper describes some simple in vitro cellular tests for direct toxicity of liposomes, particularly following intravenous (i.v.) or topical administration, including tests for haemolysis, thrombosis …
Pharmacokinetic predictions of ROS-mediated targets and …
3 days ago · We aim to examine the binding affinity of different genotoxin combinations using in silico multiple ligand simultaneous docking (MLSD) and are then bio-evaluated for cytotoxicity …
In vitro cytotoxicity evaluation of green synthesized alumina ...
Oct 1, 2024 · The cytotoxic effects of the synthesized nano-alumina were studied in cell lines LT and VERO at concentrations of 10–480 µg/mL in vitro. The cell viability of nano-alumina was …
Evaluation of acute toxicity and in vitro antitumor activity of a …
Recently, folate-coated pH-sensitive liposomes (SpHL-Fol) have been studied as a tool to enhance cellular uptake and antitumor activity of paclitaxel and DOX in breast cancer cells …
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