fancd2 fanci dna - Search
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  2. Studies of fancd2 fanci dna
    PubMed
    FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair
    Vertebrate DNA crosslink repair excises toxic replication-blocking DNA crosslinks. Numerous factors involved in crosslink repair have been identified, and mutations in their corresponding genes cause Fanconi anemia (FA). A key step in crosslink repair
    Author: Pablo Alcón
    Published: 2020/3
    Keywords: National In…
    National Center for Biotechnology Information
    FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair
    Vertebrate DNA crosslink repair excises toxic replication-blocking DNA crosslinks. Numerous factors involved in crosslink repair have been identified, and mutations in their corresponding genes cause Fanconi anemia (FA). A key step in crosslink repair
    Author: Pablo Alcón, S…
    Published: 2020/03
    DOI: 10.1038/s41594-0…
    PubMed
    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
    Fanconi anemia (FA) is characterized by congenital abnormalities, bone marrow failure, and cancer susceptibility. The central FA protein complex FANCI/FANCD2 (ID2) is activated by monoubiquitination and recruits DNA repair proteins for interstrand crosslink
    Author: Anne Olazaba…
    Published: 2024 Jan
    Keywords: CP: Molecu…
    PubMed
    FANCD2 and DNA Damage - PubMed
    Investigators have dedicated considerable effort to understanding the molecular basis underlying Fanconi Anemia (FA), a rare human genetic disease featuring an extremely high incidence of cancer and many congenital defects. Among those studies, FA group
    Author: Manoj Nepal
    Published: 2017/08/19
    Keywords: DNA dama…
    National Center for Biotechnology Information
    FANCD2 and DNA Damage - PMC - National Center for Biotechnology Information
    Investigators have dedicated considerable effort to understanding the molecular basis underlying Fanconi Anemia (FA), a rare human genetic disease featuring an extremely high incidence of cancer and many congenital defects. Among those studies, FA group
    Author: Manoj Nepal, …
    Published: 2017/08
    Publication: Int J Mol …
    National Center for Biotechnology Information
    FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures*
    In this study, we report that the purified wild-type FANCI (Fanconi anemia complementation group I) protein directly binds to a variety of DNA substrates. The DNA binding domain roughly encompasses residues 200–1000, as suggested by the truncation
    Author: Fenghua Yuan…
    Published: 2009/09/09
    Publication: J Biol Che…
    National Center for Biotechnology Information
    Structural insight into FANCI–FANCD2 monoubiquitination
    The Fanconi anemia (FA) pathway coordinates a faithful repair mechanism for DNA damage that blocks DNA replication, such as interstrand cross-links. A key step in the FA pathway is the conjugation of ubiquitin on to FANCD2 and FANCI, which is facilitated
    Author: Landing Li, Wi…
    Published: 2020/10
    Publication: Essays Bi…
     
  3. Nature
    https://www.nature.com/articles/s41586-024-07770-w

    FANCD2–FANCI surveys DNA and recognizes double- to single …

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  4. Nature
    https://www.nature.com/articles/s41594-0…

    FANCD2–FANCI is a clamp stabilized on DNA by

    WEBFeb 17, 2020 · Together, our work suggests that FANCD2–FANCI is a clamp that is locked onto DNA by ubiquitin, with distinct interfaces that …

    • Author: Pablo Alcón, Shabih Shakeel, Zhuo A. Chen, Juri Rappsilber, Juri Rappsilber, Ketan J. Patel, Lori A....
    • Publish Year: 2020

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    FANCD2 modulates the mitochondrial stress response to …
    nature.com
    The key to the FANCD2–FANCI lock - Nature
    nature.com
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  5. PubMed
    https://pubmed.ncbi.nlm.nih.gov/32066963

    FANCD2-FANCI is a clamp stabilized on DNA by ... - PubMed

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    The FANCD2–FANCI complex is recruited to DNA …
    nature.com
    Fanci-FANCD2 Promotes Genome Stability and DNA Repair …
    ashpublications.org
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  6. Nature
    https://www.nature.com/articles/s41594-022-00820-9

    The DNA-damage kinase ATR activates the FANCD2-FANCI …

    Tags:
    Fancd2 Antibody
    Fancd2 Gene
  7. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067600

    FANCD2–FANCI is a clamp stabilized on DNA by …

    Tags:
    Fancd2 and Fanci
    Publish Year:2020
    Clamp Dna
    Fanci D2
  8. PubMed
    https://pubmed.ncbi.nlm.nih.gov/38165804

    The FANCI/FANCD2 complex links DNA damage response to R …

  9. Feedback
  10. Cell Press
    https://www.cell.com/biophysj/fulltext/S0006-3495(23)01812-X

    FANCD2-FANCI is a sliding DNA clamp that specifically …

  11. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270283

    Clinical Validation of the Somatic FANCD2 Mutation (c.2022 …

    Tags:
    Fancd2 Gene
    FANCI-FANCD2
  12. PubMed
    https://pubmed.ncbi.nlm.nih.gov/28825622

    FANCD2 and DNA Damage - PubMed

    Tags:
    FANCD2
    Publish Year:2017
  13. ScienceDirect
    https://www.sciencedirect.com/science/article/pii/S0021925823000376

    DNA repair protein FANCD2 has both ubiquitination-dependent …

    Tags:
    Fancd2 and Fanci
    Fancd2 Antibody
    Fancd2 Fanci Dna Repair
  14. bioRxiv
    https://www.biorxiv.org/content/10.1101/858225v1

    FANCD2-FANCI is a clamp stabilized on DNA by ... - bioRxiv

    Tags:
    Fancd2 and Fanci
    Fancd2 Fanci Dna Repair
    Clamp Dna
    Publish Year:2019
  15. EMBO Press
    https://www.embopress.org/doi/full/10.15252/embr.202050133

    Differential functions of FANCI and FANCD2 ubiquitination …

    Tags:
    Fancd2 and Fanci
    Fancd2 Antibody
    Publish Year:2020
    Fancd2 Gene
  16. Cell Press
    https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01622-4

    The FANCI/FANCD2 complex links DNA damage response to R …

  17. American Society of Hematology
    https://ashpublications.org/blood/article/138...

    Fanci-FANCD2 Promotes Genome Stability and DNA Repair By …

    Tags:
    FANCI-FANCD2
    Publish Year:2021
  18. Nature
    https://www.nature.com/articles/s41594-022-00826-3

    The key to the FANCD2–FANCI lock - Nature

    Tags:
    DNA
    FANCI
  19. SciTechDaily
    https://scitechdaily.com/decades-old-mystery...

    Decades-Old Mystery Solved: Scientists Crack the Code of DNA …

  20. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578191

    FANCD2 and DNA Damage - PMC - National Center for …

    Tags:
    Publish Year:2017
    Published:2017/08
  21. Science | AAAS
    https://www.science.org/doi/10.1126/science.1192656

    FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand …

    Tags:
    FANCI-FANCD2
    Dna with A Cross
    Publish Year:2010
  22. Wikipedia
    https://en.wikipedia.org/wiki/FANCD2

    FANCD2 - Wikipedia

    Tags:
    DNA
    FANCD2
  23. Wiley Analytical Science
    https://analyticalscience.wiley.com/content/news...

    DNA repair discovery sparks cancer hope - 2024 - Wiley …

  24. YouTube
    https://www.youtube.com/watch?v=RtIQkD-Mf78

    FANCD2-FANCI Protein Complex Clamping DNA - YouTube

  25. Nature
    https://www.nature.com/articles/s41467-019-10408-5

    DNA requirement in FANCD2 deubiquitination by USP1-UAF1

    Tags:
    Publish Year:2019
  26. MilliporeSigma
    https://www.sigmaaldrich.com/US/en/product/mm/abe1817

    Anti-FANCI Antibody, (G4270) from rabbit, purified by affinity ...

    Tags:
    Fancd2 and Fanci
    Fancd2 Fanci Dna Repair
    Fancd2 Gene
    In stock
  27. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782037

    FANCI Protein Binds to DNA and Interacts with FANCD2 to …

    Tags:
    Fancd2 and Fanci
    FANCI-FANCD2
    Fanci D2
    Publish Year:2009
  28. 生物通
    https://www.ebiotrade.com/newsf/2024-8/20240802073023698.htm

    《Nature》新发现揭示了DNA修复途径的关键过程 - 生物通

  29. Nature
    https://www.nature.com/articles/s41388-024-03105-1

    GLI1 confers resistance to PARP inhibitors by activating the DNA …

  30. 网易
    https://www.163.com/dy/article/J8O041UF05349C3F.html

    细胞里也有现场解说和慢动作回放了！《自然》新研究，看清DNA …

  31. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588663

    Structural insight into FANCI–FANCD2 monoubiquitination - PMC

    Tags:
    Publish Year:2020
    Published:2020/10
  32. 中国科技网
    http://m.stdaily.com/index/kejixinwen/202407/897c02def94f...

    DNA损伤及修复机制谜团解开-中国科技网

  33. Nature
    https://www.nature.com/articles/ncomms12124

    The FANCD2–FANCI complex is recruited to DNA interstrand

    Tags:
    Fancd2 and Fanci
    Fancd2 Antibody
    Fancd2 Fanci Dna Repair
  34. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/gene/2177

    FANCD2 FA complementation group D2 [ (human)] - National …

    Tags:
    FANCD2
    FANCI