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- A giant cell tumor (GCT) is a noncancerous growth1234. It often occurs near a joint at the end of a bone, most commonly in the long bones of the legs and arms24. While GCTs don't usually spread to other parts of the body, they can damage surrounding tissues1. Treatment typically involves surgical removal1.
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.A giant cell tumor (GCT) is a noncancerous growth. They don’t usually spread to other parts of your body, but they typically damage surrounding tissues. They often start in your bones or in the lining of your joints. To treat a GCT, your healthcare provider usually removes the growth with surgery.my.clevelandclinic.org/health/diseases/22404-gian…A giant cell tumor is a rare, aggressive, noncancerous tumor. It often grows near a joint at the end of the bone. Most occur in the long bones of the legs and arms. They most often occur in adults between ages 20 and 40, when skeletal bone growth is complete. Symptoms may include joint pain, swelling, and limited movement.www.hopkinsmedicine.org/health/conditions-and-di…Giant-cell tumor of the bone (GCTOB), is a relatively uncommon tumor of the bone. It is characterized by the presence of multinucleated giant cells (osteoclast -like cells). Malignancy in giant-cell tumor is uncommon and occurs in about 2% of all cases. However, if malignant degeneration does occur, it is likely to metastasize to the lungs.en.wikipedia.org/wiki/Giant-cell_tumor_of_boneA giant cell tumor is one that is made up of a large number of benign (non-cancerous) cells that form an aggressive tumor—usually near the end of the bone near a joint. The location of a giant cell tumor is often in the knee, but can also involve the bones of the arms and the legs, or the flat bones, such as the sternum (breastbone) or pelvis.stanfordhealthcare.org/medical-conditions/bones-jo… - People also ask
Giant Cell Tumor of Bone - OrthoInfo - AAOS
WEBLearn about giant cell tumor of bone, a rare and aggressive benign tumor that affects young adults and can damage the bone near a joint. Find out the causes, symptoms, diagnosis, and treatment options for this …
Giant Cell Tumor (Osteoclastoma) - StatPearls - NCBI …
WEBJan 31, 2024 · Giant cell tumor (GCT) is one of the most common benign bone tumors, predominantly occurring in young adults aged 20 to 40 …
- Published: 2024/01/31
Giant-cell tumor of bone - Wikipedia
Giant-cell tumor of the bone (GCTOB), is a relatively uncommon bone tumor. It is characterized by the presence of multinucleated giant cells (osteoclast-like cells). Malignancy in giant-cell tumor is uncommon and occurs in about 2% of all cases. However, if malignant degeneration does occur, it is likely to metastasize to the lungs. Giant-cell tumors are normally benign, with unpredictable behavior.
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Giant cell tumor of bone - UpToDate
WEBJul 13, 2023 · Giant cell tumor of bone (GCTB) is a relatively rare, benign, but locally aggressive osteolytic skeletal neoplasm of young adults. First recognized in 1818 [1], it …
Giant Cell Tumour of Bone: A Comprehensive Review of …
WEBOct 13, 2023 · Giant cell tumour of bone (GCTB), first described in 1818, is a benign primary bone tumour marked by multinuclear giant cells and has a high propensity to return …
Giant Cell Tumor of Bone - An Overview - PMC - National Center …
WEBMar 12, 2015 · Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may …
Giant Cell Tumor of Bone: Review, Mimics, and New …
WEBJan 1, 2013 · Giant cell tumor (GCT) of bone is generally a benign tumor composed of mononuclear stromal cells and characteristic multinucleated giant cells that exhibit osteoclastic activity. It usually develops in long …
Giant Cell Tumor of Bone: An Update | Current Oncology Reports …
WEBMar 22, 2021 · First described in 1818 by Cooper and Travers et al. [1], giant cell tumor of bone (GCTB) is a benign primary tumor of bone with a high tendency to recur locally …
Giant Cell Tumor of Bone: An Update - PubMed
WEBMar 22, 2021 · The elucidation of the pathophysiology of giant cell tumor of bone, especially with regards to the role of nuclear factor kappa B ligand (RANKL), has led to …
Giant cell tumor of bone | Radiology Reference Article
WEBOct 13, 2023 · Learn about the radiology, pathology and epidemiology of giant cell tumor of bone, a rare and locally aggressive bone neoplasm. Find out the diagnostic criteria, …
Giant Cell Tumor - Pathology - Orthobullets
WEBGiant Cell Tumors are benign, aggressive tumors typically found in the epiphysis of long bones, most commonly at the distal femur and proximal tibia. Patients typically present …
Pathology Outlines - Giant cell tumor of bone, NOS
WEBGiant cell tumor of bone (GCTB) is a locally aggressive and rarely metastasizing neoplasm composed of neoplastic mononuclear stromal cells admixed with macrophages and …
Current Concepts in the Treatment of Giant Cell Tumors of Bone
WEBJul 21, 2021 · The 2020 World Health Organization classification defined giant cell tumors of bone (GCTBs) as intermediate malignant tumors. Since the mutated H3F3A was …
Giant cell tumor of bone - UpToDate
WEBGiant cell tumor of bone (GCTB) is a relatively rare, benign, but locally aggressive osteolytic skeletal neoplasm of young adults. First recognized in 1818 [ 1 ], it was not …
Giant Cell Tumor - Cedars-Sinai
WEBWhat is a giant cell tumor? Giant cell tumor of bone is a rare, fast-growing noncancer tumor. It most often grows in adults between ages 20 and 40 when skeletal bone growth …
Giant Cell Tumor of Bone - Medscape
WEBSep 26, 2023 · First described by Cooper and Travers in 1818, giant cell tumors (GCTs) of bone have been labeled the most challenging benign bone tumors. Although benign, …
Giant Cell Tumor: Causes, Symptoms, and Treatments - UPMC
WEBA giant cell tumor is a rare, non-cancerous growth that occurs at the end of a bone near a joint. Giant cell tumors can form in the legs, wrists, and hips of people who are in their …
Giant Cell Tumor - Columbia Neurosurgery in New York City
WEBA giant cell tumor (GCT) of bone is a benign (noncancerous) bone tumor that typically develops near the joints of the knee, wrist, shoulder, or spine. At the Spine Hospital at …
Giant cell tumor of bone - Children's Hospital of Philadelphia
WEBGiant cell tumors are benign bone tumors that can grow aggressively and destroy bone close to a joint. Typically they occur close to the knee, wrist, ankle or hip. While …
Metastatic giant cell tumour of bone: a narrative review of …
WEBFeb 10, 2022 · Giant cell tumour of bone (GCTB) is a locally aggressive bone neoplasm with a rare tendency to metastasise, most commonly to the lungs. The management of …
Giant cell tumor of bone of temporal bone and skull base: report …
WEBSep 2, 2024 · Objective Five cases of giant cell tumor of bone (GCTB) in the head and neck region were reported, with a main focus on the radiological findings to identify …
Unusual Histopathological Challenges in Diagnosis of Giant Cell …
WEBIntroduction: Giant cell tumor of bone (GCTB) is a rare yet locally aggressive neoplasm primarily affecting young adults. Its hallmark features include multinucleated osteoclast …
Giant cell tumor of bone revisited - PMC - National Center for ...
WEBSep 14, 2017 · Giant cell tumor (GCT) of bone is a locally aggressive benign neoplasm that is associated with a large biological spectrum ranging from latent benign to highly …
Clinicopathologic and prognostic characteristics of tumor …
WEB5 days ago · Currently, tumor budding (TB) is defined as an important factor for a poor prognosis in various types of cancers. The authors identified a significant presence of TB …
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