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- Studies of glutamine synthetase gene
GLUL Gene - GeneCards | GLNA Protein | GLNA Antibody
Oct 2, 2024 · It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation.
Glutamine synthetase - Wikipedia
GS is subject to reversible covalent modification. Tyr of all 12 subunits can undergo adenylylation or deadenylylation by adenylyl transferase (AT), a bifunctional regulatory enzyme. Adenylylation is a post-translational modification involving the covalent attachment of AMP to a protein side chain. Each adenylylation requires an ATP and complete inhibition of GS requires 12 ATP. …
Wikipedia · Text under CC-BY-SA license- Estimated Reading Time: 9 mins
Glutamine Synthetase: Localization Dictates Outcome - PMC
Glutamine synthetase (GS) is the adenosine triphosphate (ATP)-dependent enzyme that catalyses the synthesis of glutamine by condensing ammonium to glutamate. In the circulatory …
Role of glutamine synthetase in angiogenesis beyond ... - Nature
Aug 29, 2018 · Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. It is expressed by endothelial cells, but surprisingly …
- Author: Guy Eelen, Guy Eelen, Charlotte Dubois, Anna Rita Cantelmo, Anna Rita Cantelmo, Jermaine Goveia, Ulr...
- Publish Year: 2018
2752 - Gene ResultGLUL glutamate-ammonia ligase [ (human)]
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This …
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GLUL glutamate-ammonia ligase [Homo sapiens (human)]
Oct 6, 2024 · The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent …
Glutamine synthetase - Homo sapiens (Human) | UniProtKB
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (PubMed: 16267323, PubMed: 30158707, PubMed: 36289327). Its role depends on …
Molecular Mechanisms of Glutamine Synthetase Mutations that …
Feb 2, 2016 · Glutamine synthetase (GS) catalyzes ATP-dependent ligation of ammonia and glutamate to glutamine. Two mutations of human GS (R324C and R341C) were connected to …
UniProt
Jan 23, 2007 · Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (PubMed: 16267323, PubMed: 30158707, PubMed: 36289327). Its …
14645 - Gene ResultGlul glutamate-ammonia ligase [ (house …
Mar 5, 2024 · genetic deletion of Glul in endothelial cells impairs vessel sprouting during vascular development, whereas pharmacological blockade of glutamine synthetase suppresses …
Glutamine Synthetase: Role in Neurological Disorders
Glutamine synthetase (GS) is an ATP-dependent enzyme found in most species that synthesizes glutamine from glutamate and ammonia. In brain, GS is exclusively located in astrocytes …
Role of glutamine synthetase in angiogenesis beyond glutamine …
Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. It is expressed by endothelial cells, but surprisingly shows negligible …
Glutamine synthetase (GS) knockout (KO) using CRISPR ...
Jun 28, 2023 · The glutamine synthetase (GS)-based Chinese hamster ovary (CHO) selection system is an attractive approach to efficiently identify suitable clones in the cell line generation …
Glutamine Synthetase - an overview | ScienceDirect Topics
Glutamine synthetase is a cytosolic enzyme that catalyzes the synthesis of glutamine from glutamate and free NH4+ in an ATP-dependent reaction (Fig. 1). The human gene encoding …
Redundancy and metabolic function of the glutamine synthetase …
Jan 22, 2015 · Glutamine synthetase (GS; EC: 6.3.1.2, L-glutamate: ammonia ligase ADP-forming) is a key enzyme in ammonium assimilation and metabolism in higher plants.
UniProt
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the …
Advances in the functional study of glutamine synthetase in plant ...
Aug 1, 2022 · Plant glutamine synthetase (GS, EC6.3.1.2) catalyzes the synthesis of glutamine from glutamate and ammonium ions and acts as a key enzyme in the nitrogen metabolic …
948370 - Gene ResultglnA glutamine synthetase [] - National …
May 2, 2024 · Gene ID: 948370, updated on 2-May-2024. Summary. Induced during biofilm formation. [More information is available at EcoGene: EG10383]. Glutamine synthetase …
Glutamine synthetase gene evolution in bacteria - PubMed
The evolution of the prokaryotic glutamine synthase (GS) genes, namely the GSI and GSII isoforms, has been investigated using the second codon positions, which have previously …
The glutamine synthetase gene family in Populus - BMC Plant …
Aug 25, 2011 · Glutamine synthetase (GS; EC 6.3.1.2, L-glutamate: ammonia ligase ADP-forming) catalyzes the ATP-dependent addition of ammonium (NH 4+) to the γ-carboxyl group of …
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