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- Central to maintaining a healthy epithelium are intestinal stem cells (ISCs), which are essential for replenishing the intestinal epithelium throughout an individual’s lifespan. Recent research has unveiled the intricate interplay between ISCs and their niche, which includes various cell types, extracellular components, and signaling molecules.
www.nature.com/articles/s12276-024-01179-1 - People also askQ&A: Guthealthmicrosoftstart.msn.com
WEBMar 1, 2024 · Central to maintaining a healthy epithelium are intestinal stem cells (ISCs), which are essential for replenishing the intestinal epithelium throughout an individual’s lifespan. Recent...
See results only from nature.comRoles of intestinal epithelial …
Open access. Published: 26 May 2017. Roles of intestinal epithelial cells in the …
Adult intestinal stem cells: cr…
Published: 11 December 2013. Adult intestinal stem cells: critical drivers of …
A growth factor-free culture …
42 Citations. 3 Altmetric. Metrics. Abstract. Lgr5 + intestinal stem cells (ISCs) drive …
Intestinal stem cells - Latest …
Claudin-7 is essential for the maintenance of colonic stem cell homoeostasis via …
WEBAug 8, 2022 · Intestinal stem cells (ISCs) play an important role in maintaining intestinal homeostasis via promoting a healthy gut barrier. Within the stem cell niche, gut …
- DOI: 10.7150/ijbs.72600
- Published: 2022
- Publication: Int J Biol Sci. 2022; 18(13): 5185-5206.
- Studies of gut stem cell maintenance
WEBIn response to diverse stress stimuli from a variety of external and internal cues, constant intestinal epithelial adaptation is required. The intestinal …
- Author: Gizem Calibasi-Kocal, Gizem Calibasi-Kocal, Omid Mashinchian, Yasemin Basbinar, Ender Ellidokuz, Chi...
- Publish Year: 2021
WEBJan 18, 2019 · In addition to the actively cycling ISCs that maintain daily homeostasis, accumulating evidence supports the existence of other pools of stem/progenitor cells …
WEBSep 27, 2022 · Open Access. Gut microbiota-stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis. Ning Ma, Xiyue Chen, Lee J. Johnston, Xi Ma. First published: 27 September 2022. …
WEBGenetic and pharmacologic evidence indicates a pivotal role of canonical Wnt signaling during intestinal homeostasis and Lgr5 + ISC proliferation with crypt/villus/Lgr5 + ISC loss observed upon diverse manipulations …
WEBMar 8, 2022 · The midgut is maintained by pluripotent intestinal stem cells (ISCs) that self-renew and transiently differentiate into non-dividing enteroblasts (EBs) and pre-enteroendocrines (pre-EEs), which …
WEBSep 16, 2016 · Here we review the current models of stem cell‐driven intestinal epithelial regeneration, with particular emphasis on human models; discuss how advancements in …
Stem Cell Signaling Pathways in the Small Intestine - PMC
WEBMar 16, 2020 · The ability of stem cells to divide and differentiate is necessary for tissue repair and homeostasis. Appropriate spatial and temporal mechanisms are needed. …
Regulation of Drosophila intestinal stem cell maintenance and ...
WEBDec 17, 2014 · Abstract. Tissue stem cells divide to self-renew and generate differentiated cells to maintain homeostasis. Although influenced by both intrinsic and extrinsic …
Muscarinic receptor M3 contributes to intestinal stem cell …
WEBJul 9, 2021 · The ability of intestinal stem cells (ISCs) to divide and differentiate is necessary for tissue repair and homeostasis. Maintenance of a functional intestine …
WEBCentral to maintaining a healthy epithelium are intestinal stem cells (ISCs), which are essential for replenishing the intestinal epithelium throughout an individuals...
Stem cells in homeostasis and cancer of the gut - PubMed
WEBMar 30, 2019 · Homeostasis. Humans. Neoplastic Stem Cells / pathology* Signal Transduction. Stem Cell Niche* The intestinal epithelial lining is one of the most rapidly …
Regulation of Drosophila intestinal stem cell maintenance and ...
WEBNov 28, 2014 · Introduction. During homeostasis, tissue stem cells maintain the stem cell population through self‐renewal and give rise to differentiating progeny to replace …
Autocrine and paracrine unpaired signaling regulate intestinal …
WEBDec 15, 2012 · Upd1 regulates intestinal stem cell maintenance. (A) Knockdown of each upd gene with the esg F/O system shows that Upd1 but not Upd2 or Upd3 is required for …
Modulation of stem cell fate in intestinal homeostasis, injury and ...
WEBMay 5, 2023 · Go to: Abstract. The mammalian intestinal epithelium constitutes the largest barrier against the external environment and makes flexible responses to various types …
IDDF2021-ABS-0074 Gut microbial metabolite of tryptophan …
WEBThe mitochondrial OXPHOS ability of intestinal crypt stem cells in CRS mice and control mice was assessed using Seahorse mitochondrial stress test. 16S rRNA analysis was …
Identifying the initial steps in colorectal cancer formation
WEB1 day ago · Research led by Weill Cornell Medicine provides new evidence that most colorectal cancers begin with the loss of intestinal stem cells, even before cancer …
Stem Cells in Repair of Gastrointestinal Epithelia - PMC
WEBJun 14, 2017 · Each unit can be subdivided into a villus, protruding into the gut lumen and containing differentiated cells responsible for digestion and absorption, and crypt of …
Impact of microbiota specific circulating memory T cells in …
WEB3 days ago · 2572 Background: The gut microbiota influences the cancer immune set point and response to immune checkpoint inhibitors (ICB), participating in the differentiation …
Gut bacteria boost immune response to fight tumors
WEBMay 20, 2024 · Microbes also can leak out of the gut and trigger an immune response in the tumor or activate gut T cells that migrate to the tumor to mount an attack, Colonna …
Antagonizing vasoactive intestinal peptide (VIP) receptors with …
WEB3 days ago · Vasoactive intestinal peptide (VIP) is an emerging checkpoint pathway for T cell function, which expresses VIP receptors (VIPR) and is abundantly expressed by …
Metabolic regulation of somatic stem cells in vivo - Nature
WEBPublished: 28 February 2022. Metabolic regulation of somatic stem cells in vivo. Corbin E. Meacham, Andrew W. DeVilbiss & Sean J. Morrison. Nature Reviews Molecular Cell …
The histone demethylase Kdm6b regulates the maturation and …
WEBJan 9, 2022 · Kdm6b controls the heterogeneity and TCR repertoire of small intestinal IELs. Among thymocytes (DN, DP, CD4 +, and CD8 +), spleen CD4 + and CD8 + T …
Author Correction: c-Maf-dependent Treg cell control of intestinal …
WEBMay 23, 2024 · Author Correction: c-Maf-dependent T reg cell control of intestinal T H 17 cells and IgA establishes host–microbiota homeostasis. Christian Neumann 1,2, Jonas …
Mechanisms of axonal support by oligodendrocyte-derived
WEBMay 31, 2023 · In all bilaterian species, neurons and their axons are associated with glial cells. Indeed, neuronal networks require glial instruction and support to be formed and …
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