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  1. Hill equation (biochemistry) - Wikipedia

    • In biochemistry and pharmacology, the Hill equation refers to two closely related equations that reflect the binding of ligands to macromolecules, as a function of the ligand concentration. A ligand is "a substance that forms a complex with a biomolecule to serve a biological purpose" (ligand definition), and a macromolecule is a very large molecule, such a… See more

    Proportion of ligand-bound receptors

    The Hill equation is commonly expressed in the following ways.
    ,
    where:
    • … See more

    Tissue response

    A distinction should be made between quantification of drugs binding to receptors and drugs producing responses. There may not necessarily be a linear relationship between the two values. In contrast to this article's pre… See more

    Hill coefficient

    The Hill coefficient is a measure of ultrasensitivity (i.e. how steep is the response curve).
    The Hill coefficient, or , may describe cooperativity (or possibly other biochemical properties, … See more

    Reversible form

    The most common form of the Hill equation is its irreversible form. However, when building computational models a reversible form is often required in order to model product inhibition. For this reason, Hofmeyr and Cornis… See more

    Applications

    The Hill equation is used extensively in pharmacology to quantify the functional parameters of a drug and are also used in other areas of biochemistry.
    The Hill equation can be used to describe dose-respo… See more

    Limitations

    Because of its assumption that ligand molecules bind to a receptor simultaneously, the Hill equation has been criticized as a physically unrealistic model. Moreover, the Hill coefficient should not be considered … See more

     
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  2. Hill Equation #biochemistry #education #maths #tutorial

     
  3. Equation for a Hill plot (cooperative enzymes) - YouTube

  4. Hill Plot Explained: Definition, Examples, Practice & Video

  5. Hill Equation Explained: Definition, Examples, Practice ... - Pearson

  6. Hill Equation - Interactive Graph - PhysiologyWeb

    Oct 22, 2014 · The interactive graph provided below allows for a good understanding of the Hill equation, how the reaction velocity changes as a function of the substrate concentration, and how changes in V max, K 0.5, and …

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  8. Hill Equation | Channels for Pearson+

  9. Hill equation - YouTube

  10. Hill Equation - (Biological Chemistry I) - Vocab, Definition

  11. Hill equation and plot | PPT - SlideShare

    May 25, 2019 · The document discusses the Hill equation, which was formulated by Archibald Hill in 1910 to describe the sigmoidal oxygen binding curve of hemoglobin. The Hill equation can be used to describe the fraction of a …

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  12. BioMath: Rational Applications

  13. Hill Coefficient: Your Complete MCAT Guide - BeMo

  14. How to (properly) use the Hill equation to fit binding data?

  15. The Hill analysis and co-ion–driven transporter kinetics - PMC

  16. Hill equation - Encyclopedia of Mathematics

  17. Hill Plot | Channels for Pearson+

  18. HbO.Severinghaus | Interagency Modeling and Analysis Group

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