Definitions  In 2011, a joint initiative by the European and United States Centers for Disease … See more

Prevalence  Since the 1980s, resistant strains have become increasingly common causes of nosocomial infections globally [7-11]. In a 2009 report of surveillance data from more t… See more

Heavy use of third generation cephalosporins, aztreonam, and imipenem has contributed to the problem of carbapenem resistance [17,29]. There are also report… See more

Although polymyxins, such as colistin, usually have in vitro activity against Acinetobacter [32,33], resistance to polymyxins has been observed [34,35]. In one surveill… See more

Prognosis  Patients with infection due to resistant strains appear to have higher mortality than patients with infection due to susceptible strains [43]. In a systematic review of o… See more

Mechanisms  Acinetobacter species are capable of accumulating multiple antibiotic resistance genes, leading to the development of multidrug-resistant or extensivel… See more