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  1. Arteriosclerosis atherosclerosis - Symptoms

    Verified Expert
    Contact your provider if experiencing new, severe, or persistent symptoms.

    Plaque build-up happens gradually. Mild arteriosclerosis may not have any symptoms.

    Symptoms of moderate to severe arteriosclerosis depend on the arteries affected; moderate to severe arteriosclerosis symptoms include:

    • Chest pain or angina
    • Pain in your leg, arm, and anywhere else that has a blocked artery
    • Shortness of breath
    • Fatigue
    • Confusion, which occurs if the blockage affects circulation to your brain
    • Muscle weakness in your legs from lack of blood circulation

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    Causes

    Verified Expert

    • The exact cause is unknown. The damage to the inner lining of the artery may lead to arteriosclerosis. The major possible causes of damage to the arteries are:
    • The major possible causes of damage to the arteries are:
    • High blood pressure
    • High cholesterol
    • High triglycerides, a type of fat (lipid) in blood
    • Consumption of tobacco in any form, either chewable or smoking
    • Obesity
    • Diabetes
    • Inflammation from diseases, such as arthritis, lupus or infections, or Inflammation of unknown cause

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    Prevention

    Verified Expert

    A healthy lifestyle helps in slowing down the progression of, or in reversal of atherosclerosis.

    • Exercise regularly
    • Maintain a healthy weight
    • Manage blood pressure
    • Quit smoking
    • Reduce stress
    • Avoid foods containing saturated and trans fat

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    What is atherosclerosis?
    Access free multiple choice questions on this topic. Atherosclerosis is a chronic inflammatory disease of the arteries and is the underlying cause of about 50% of all deaths in westernized society.
    ncbi.nlm.nih.gov

    Complications

    Verified Expert

    Arteriosclerosis can cause the following conditions:

    • Coronary artery disease: plaque deposits in coronary artery blocks the blood flow.
    • Carotid artery disease: carotid artery present in neck and the supply of blood to the brain get affected due to plaque buildup in the arteries.
    • Peripheral artery disease: narrowing of the arteries present in the lower body.
    • Kidney disease: plaque deposition in renal arteries. Arteriosclerosis of these arteries may lead to kidney failure.

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    arteriosclerosis atherosclerosis_en
    Microsoft Start Health

    Treatment

    Verified Expert

    Lifestyle changes, such as eating a healthy diet and exercising, are often recommended. Management of the condition involves medications and surgery in severe cases.

    Medication

    Angiotensin-converting enzyme (ACE) inhibitors: Lowers blood pressure.

    Benazepril . Captopril . Enalapril

    Calcium channel blockers: Helps in lowering blood pressure.

    Nifedipine

    Diuretics: Diuretics lower blood pressure.

    Indapamide

    Beta blockers: Can lower blood pressure and slow down progression of atherosclerosis.

    Acebutolol . Betaxolol

    Statins: Lower the levels of bad cholesterol (LDL).

    Atorvastatin . Fluvastatin

    Anti platelet medications: Helps in reducing the formation of platelet clumps in narrowed arteries.

    Aspirin

    Fibrinolytic enzymes: Therapy to break the clot apart using clot-dissolving enzymes.

    Streptokinase . Urokinase

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    Source: Focus Medica. For informational purposes only. Consult a medical professional for advice. | Disclaimer: Opinions are from external health professionals and should not be considered as Microsoft's opinion or a substitute for professional help. Consult a health professional for medical advice.
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    Table of Contents
    Symptoms
    Causes
    Prevention
    What is atherosclerosis?
    Complications
    Health guide
    Treatment
     

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  2. What is Atherosclerotic heart disease?

    Answered by verified global health professionals
    Dr. Himanshu J. VatsMBBS · 1 years of exp

    Atherosclerotic coronary artery disease (CAD) is a condition characterized by the buildup of atherosclerotic plaques within the coronary arteries, which supply oxygen-rich blood to the heart muscle. This buildup can lead to a rang... Read more
    Dr. Maurya RaghavMBBS · 3 years of exp

    Atherosclerosis is the building up of fats and cholesterol (plaques) in the walls of arteries, causing the narrowing of arterial walls. This leads to obstruction of blood flow and clotting of blood in the arteries.

    Read all answers on Heart Diseases

    Disclaimer: Opinions are from external health professionals and should not be considered as Microsoft's opinion or a substitute for professional help. Consult a health professional for medical advice.
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  3. Atherosclerotic cardiovascular disease (ASCVD)12345:
    • Involves plaque buildup in artery walls.
    • Includes conditions such as acute coronary syndrome and peripheral artery disease.
    • Can cause heart attack, stable or unstable angina, stroke, transient ischemic attack (TIA), or aortic aneurysm.
    • Results from repeated injury to artery walls due to factors like high blood pressure, tobacco smoke, diabetes, and high cholesterol.
    • Common cause of heart attack and stroke.
    Learn more:
    Atherosclerotic cardiovascular disease (ASCVD) involves plaque buildup in artery walls, which includes conditions such as acute coronary syndrome and peripheral artery disease, and can cause a heart attack, stable or unstable angina, stroke, transient ischemic attack (TIA) or aortic aneurysm.

    What is Atherosclerosis? | American He…

    www.heart.org/en/health-topics/cholesterol/about-c…
    Atherosclerotic cardiovascular disease (ASCVD) is a condition that causes arteries to narrow, restricting healthy blood flow to organs as well as the arms and legs. When ASCVD blocks blood flow to the heart or brain, it can lead to heart attack and strokes.

    What Is Atherosclerotic Cardiovascular …

    www.goodrx.com/health-topic/heart/atherosclerotic …
    Atherosclerosis is caused by repeated injury to the walls of arteries. Many factors contribute to this injury, including high blood pressure, tobacco smoke, diabetes, and high levels of cholesterol in the blood. Blood vessel blockage due to atherosclerosis is a common cause of heart attack and stroke.

    Atherosclerosis - Heart and Blood Vess…

    www.merckmanuals.com/home/heart-and-blood-ve…
    Atherosclerosis is a narrowing of the arteries caused by a buildup of cholesterol plaque. It may lead to stroke, heart attacks, dementia, and other health challenges. When plaque builds up and the arteries become hard and inflamed, blood has trouble flowing through them to the rest of the body.

    Atherosclerosis: Symptoms, Causes, Di…

    www.healthline.com/health/atherosclerosis
    Atherosclerosis -- sometimes called hardening of the arteries -- can slowly narrow the arteries throughout your body. When atherosclerosis affects arteries that carry blood to the heart muscle, it’s called coronary artery disease, or CAD. That’s the No. 1 killer of Americans. Most of those deaths are from heart attacks caused by blood clots.

    Atherosclerosis and Coronary Artery Dis…

    www.webmd.com/heart-disease/atherosclerosis-an…
     
  4. People also ask
    Is atherosclerosis a major cause of cardiovascular disease?
    Atherosclerosis is considered the major cause of cardiovascular diseases. Atherosclerotic cardiovascular disease mainly involves the heart and brain: ischemic heart disease (IHD) and ischemic stroke. IHD and stroke are the world's first and fifth causes of death respectively.

    Atherosclerosis - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    How dangerous is cardiovascular disease?

    Dr. Howard E. LeWine

    M.D. Chief Medical Editor, Harvard Health Publishing · 40 years of exp

    The level of danger from cardiovascular disease depends on the severity; the organs at risk, especially the heart and brain, and whether the person with cardiovascular disease is taking optimal therapy for the condition. Significant risks from fatty plaque buildup in the body’s arteries not only include the high risk of heart attack and stroke, but also kidney impairment and peripheral artery disease (poor circulation that can lead to amputation).
    3 more answers
    bing.com
    What is atherosclerosis?
    Access free multiple choice questions on this topic. Atherosclerosis is a chronic inflammatory disease of the arteries and is the underlying cause of about 50% of all deaths in westernized society.

    Atherosclerosis - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
    Is heart and blood vessel disease related to atherosclerosis?
    Heart and blood vessel disease, also called heart disease, includes numerous problems, many of which are related to atherosclerosis. Atherosclerosis is a condition that develops when a substance called plaque builds up in the walls of the arteries. This buildup narrows the arteries, making it harder for blood to flow through.

    What is Cardiovascular Disease? | American Heart Association

    heart.org
    Do atherosclerotic cardiovascular diseases affect morbidity and mortality?
    Atherosclerotic cardiovascular diseases make up the largest group of vascular diseases in the United States and have the greatest effect on morbidity and mortality. Comparisons of populations show large differences in incidence and mortality from the atherosclerotic cardiovascular diseases and in the underlying pathological process—atherosclerosis.

    Atherosclerotic Cardiovascular Diseases - Diet and Health - NCBI Books…

    ncbi.nlm.nih.gov
    What is atherosclerotic cardiovascular disease (ASCVD)?
    Atherosclerotic cardiovascular disease (ASCVD) involves plaque buildup in artery walls, which includes conditions such as acute coronary syndrome and peripheral artery disease, and can cause a heart attack, stable or unstable angina, stroke, transient ischemic attack (TIA) or aortic aneurysm. Download What does ASCVD mean? (PDF) | Spanish (PDF)

    What is Atherosclerosis? - American Heart Association

    heart.org
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  5. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Arteriosclerosis / atherosclerosis - Symptoms and causes - Mayo …

     
  6. Cleveland Clinic
    https://my.clevelandclinic.org/health/dis…

    Atherosclerosis: Symptoms, Causes & Treatment

    Atherosclerosis is a hardening of your arteries from plaque buildup that can cause heart attack, stroke and other complications. Learn about the stages, diagnosis and prevention of this common condition.

  7. WebMD
    https://www.webmd.com/heart-disease…

    Atherosclerosis: Symptoms, Causes, Diagnosis, and …

    Nov 7, 2023 · Atherosclerosis causes heart attacks, strokes, and peripheral vascular disease. Learn about causes, symptoms, risk factors, diagnosis, and treatments.

  8. American Heart Association
    https://www.heart.org/.../atherosclerosis

    What is Atherosclerosis? | American Heart Association

    Feb 16, 2024 · Atherosclerosis is the buildup of plaque in artery walls, which can lead to atherosclerotic cardiovascular disease (ASCVD). Learn about the causes, symptoms, complications and prevention of ASCVD from the American Heart …

    What is Cardiovascular Disease? | American Heart AssociationJan 9, 2024
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    How High Blood Pressure Can Lead to a Heart Attack ...Oct 30, 2016
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  9. Cleveland Clinic
    https://my.clevelandclinic.org/health/diseases/24870

    Arteriosclerosis: Symptoms, Causes & Treatment - Cleveland Clinic

  10. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Arteriosclerosis / atherosclerosis - Diagnosis and treatment

  11. NHLBI, NIH
    https://www.nhlbi.nih.gov/health/athero…

    Atherosclerosis - What Is Atherosclerosis? - NHLBI, NIH

    Oct 28, 2024 · Atherosclerosis is a common condition that leads to heart disease and other health problems. It’s caused by the buildup of sticky cholesterol plaque in the arteries, but it’s preventable and treatable.

  12. American Heart Association
    https://www.heart.org/en/professional/q…

    ASCVD | American Heart Association

    ASCVD is a group of conditions caused by plaque buildup in arteries, such as CHD, stroke, and peripheral artery disease. The American Heart Association provides educational resources and tools for health care professionals to …

  13. Johns Hopkins Medicine
    https://www.hopkinsmedicine.org/.../at…

    Atherosclerosis - Johns Hopkins Medicine

    Atherosclerosis is a condition where plaque builds up in the arteries, reducing blood flow and increasing the risk of heart attack, stroke, and other complications. Learn about the causes, symptoms, diagnosis, treatment, and prevention of …

  14. MedlinePlus
    https://medlineplus.gov/atherosclerosis…

    Atherosclerosis | Arteriosclerosis - MedlinePlus

    Mar 6, 2024 · Atherosclerosis, which develops from plaque buildup, is a common type of arteriosclerosis. Atherosclerosis can affect most of the arteries in the body. It has different names, based on which arteries are affected: Coronary artery …

  15. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK507799

    Atherosclerosis - StatPearls - NCBI Bookshelf

    Sep 10, 2020 · Atherosclerosis is a chronic inflammatory disease in which there is a build up of plaques inside arteries. These plaques are principally composed of lipids that induce an inflammatory reaction causing turbulent flow with …

  16. Yale Medicine
    https://www.yalemedicine.org/conditions/atherosclerosis

    Atherosclerosis > Fact Sheets - Yale Medicine

  17. Healthline
    https://www.healthline.com/health/atherosclerosis

    Atherosclerosis: Symptoms, Causes, Diagnosis, and Treatment

  18. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK218744

    Atherosclerotic Cardiovascular Diseases - Diet and Health - NCBI …

  19. GoodRx
    https://www.goodrx.com/health-topic/heart/...

    Atherosclerotic Cardiovascular Disease: What It Is and Treatment …

  20. The Merck Manuals
    https://www.merckmanuals.com/.../atherosclerosis

    Atherosclerosis - Atherosclerosis - Merck Manual Professional …

  21. Nature
    https://www.nature.com/articles/s41572-019-0106-z

    Atherosclerosis - Nature Reviews Disease Primers

  22. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/heart-disease

    Heart disease - Symptoms and causes - Mayo Clinic

  23. nih.gov
    https://pmc.ncbi.nlm.nih.gov/articles/PMC8387275

    Oral health and atherosclerotic cardiovascular disease: A review

  24. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Coronary artery disease - Symptoms and causes - Mayo Clinic

  25. Nature
    https://www.nature.com/articles/s41598-024-81352-8

    Plasma exosomes from patients with coronary artery disease …