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International Scoring System for Diagnosis of Autoimmune Hepatitis Sex: Female +2: HLA: DR3 or DR4 +1: AP:AST (or ALT) ratio > 3 < 1.5-2 +2: Immune disease

Approach to Diagnosis. The diagnosis of autoimmune hepatitis has been codified by an international panel, and these criteria must now be applied to all patients suspected to have the disease ...

From Alvarez F, Berg PA, Bianchi FB, et al. International Auto-immune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31(5):929-938.

Autoimmune hepatitis (AIH) is an immune-mediated necroinflammatory condition of the liver that primarily targets hepatocytes. It affects all age groups. The clinical, biochemical, and histological ...

Celiac disease has been described as a concurrent disorder in 3% of patients with autoimmune hepatitis. It also has been found in PBC, [ 22 ] PSC, [ 23 ] and autoimmune cholangitis. [ 24 ]

The diagnosis of AIH is a probability best reflected in the AIH diagnostic score published in 1993 and revised in 1999 by the International Autoimmune Hepatitis Group (IAHG).

High-resolution DNA-based techniques have indicated that the principal susceptibility factors for autoimmune hepatitis associated with SMA and ANA expression reside on the DRB1 gene, and they are ...

Autoimmune hepatitis is characteristically responsive to corticosteroids, often used in combination with azathioprine to obtain a steroid-sparing effect. For primary biliary cirrhosis ...

Autoimmune hepatitis recurs in approximately one third and may be detected up to 10 years or more post-transplant. There are no agreed-on criteria for the diagnosis, and differentiation from ...

Criteria for the Diagnosis of Recurrent Autoimmune Hepatitis Liver transplant for AIH. Auto-antibodies in significant titer (>1:40) Sustained rise in serum aminotransferase activity (>twice normal)