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See all on WikipediaCationic liposome - Wikipedia
Cationic liposomes are spherical structures that contain positively charged lipids. Cationic liposomes can vary in size between 40 nm and 500 nm, and they can either have one lipid bilayer (monolamellar) or multiple lipid bilayers (multilamellar). The positive charge of the phospholipids allows cationic … See more
In the 1960s, Alec D. Bangham discovered liposomes as concentric lipid bilayers surrounding an aqueous center, based on his research at the … See more
The use of cationic lipids helps to enhance the overall stability and efficiency of liposomes. Although cationic lipids themselves are able to encapsulate nucleic acids into … See more
Cationic liposomes can deliver nucleic acids into the cell through an endocytotic pathway or through cell membrane fusion. Fusogenic cationic liposomes almost exclusively deliver … See more
Cationic liposomes are manufactured similarly to liposomes. There are multiple processes that can be used to form cationic liposomes, such as sonication, extrusion, … See more
Cancer Drug Delivery
EndoTAG-1
Paclitaxel (PTX) is a chemotherapy medication used to … See moreWikipedia text under CC-BY-SA license Liposomes: structure, composition, types, and clinical applications
WEBMay 13, 2022 · Cationic liposomes are suitable for delivering various negatively charged macromolecules such as DNA, RNA, and oligonucleotides because their negative …
- DOI: 10.1016/j.heliyon.2022.e09394
- Published: 2022/05
- Publication: Heliyon. 2022 May; 8(5): e09394.
Cationic Liposome - an overview | ScienceDirect Topics
WEBCationic liposome is one of the most commonly used nonviral gene delivery vectors and it is widely used as a standard gene vector especially for in vitro transfection (Ozpolat et al., …
Immunological and Toxicological Considerations for the Design of …
WEBJan 22, 2020 · Cationic liposomes, which are largely studied for gene delivery, are known to elicit toxicity in macrophages, macrophage-like cells, and monocyte-like cells, as well …
Barriers and Strategies of Cationic Liposomes for Cancer Gene …
WEBSep 9, 2020 · Cationic liposomes (CLs) have been regarded as the most promising gene delivery vectors for decades with the advantages of excellent biodegradability, …
Formation and purification of tailored liposomes for drug ... - Nature
WEBSep 21, 2017 · Liposomes are lipid based bilayer vesicles that can encapsulate, deliver and release low-soluble drugs and small molecules to a specific target site in the body. …
Current advances in the use of exosomes, liposomes, and
WEBApr 4, 2022 · Liposomes, artificial fat bubbles, are long known for their capacity to encapsulate a diverse range of bioactive molecules and release the payload in a …
Evaluation of novel cationic gene based liposomes with ... - Nature
WEBOct 22, 2019 · Cationic lipid-mediated gene transfer is one of the most commonly used non-viral vectors, which have been shown to be a safe and effective carrier. However, …
Barriers and Strategies of Cationic Liposomes for ... - ScienceDirect
WEBSep 11, 2020 · Cationic liposomes (CLs) have been regarded as the most promising gene delivery vectors for decades with the advantages of excellent biodegradability, …
Lipid Nanoparticles─From Liposomes to mRNA Vaccine Delivery, …
WEBJun 28, 2021 · Liposomes, an early version of LNPs, are a versatile nanomedicine delivery platform. A number of liposomal drugs have been approved and applied to medical …
On the uptake of cationic liposomes by cells: From changes in
WEBCations. In this study, we assessed the capacity of a previously reported engineered liposomal formulation, which had been tested against model membranes mimicking the …
Methods of Liposomes Preparation: Formation and Control …
WEBFeb 28, 2022 · One approach to enhance the colloidal stability of liposomes consists of the incorporation of charged components (such as anionic/cationic lipids or charged …
Cationic liposomes for gene delivery - PubMed
WEBCationic liposome-DNA complexes (lipoplexes) constitute a potentially viable alternative to viral vectors for the delivery of therapeutic genes. This review will focus on various …
Cationic liposome–nucleic acid nanoparticle assemblies with ...
WEBCationic liposomes (CLs) are synthetic carriers of nucleic acids in gene delivery and gene silencing therapeutics. The introduction will describe the structures of distinct liquid …
Cationic liposomes as vaccine adjuvants - PubMed
WEBCationic liposomes are lipid-bilayer vesicles with a positive surface charge that have re-emerged as a promising new adjuvant technology. Although there is some evidence …
Membrane Fusion with Cationic Liposomes: Effects of Target …
WEBMay 6, 2020 · To determine what role the lipid composition of “target” membranes might have in promoting fusion with cationic liposomes, we have examined the ability of large …
Advances and Challenges of Liposome Assisted Drug Delivery
WEBDec 1, 2015 · Schematic representation of the different types of liposomal drug delivery systems. (A) Conventional liposome—Liposomes consist of a lipid bilayer that can be …
Liposomes: structure, composition, types, and clinical applications
WEBCationic liposomes are suitable for delivering various negatively charged macromolecules such as DNA, RNA, and oligonucleotides because their negative charge and rather a …
DOTAP Modified Formulations of Aminoacid Based Cationic …
WEB5 days ago · DOTAP Modified Formulations of Aminoacid Based Cationic Liposomes for Improved Gene Delivery and Cell Viability. Srilakshmi V Patri, Corresponding Author ...
Cationic Liposomes Carrying siRNA: Impact of Lipid Composition …
WEBApr 24, 2018 · Liposomes containing 50% of DOPE induced a mRNA silencing of around 80%. This study allowed us to highlight crucial parameters in order to develop lipoplexes …
Liposomes with Low Levels of Grafted Poly(ethylene glycol) …
WEB2 days ago · Destabilization of IL and L-PLD by anti-PEG IgG seemed to proceed by fusion of liposomes to form large liposomes as well as multilamellar and multivesicular …
Structure and Function of Cationic and Ionizable Lipids for Nucleic ...
WEBJan 4, 2023 · Cationic liposomes can condense and encapsulate DNA or other genetic materials in LNP formulations for intracellular delivery. Cationic liposome and DNA …
Recent advances in essential oils and their nanoformulations for ...
WEB1 day ago · To address this, material scientists have developed nanoformulations for EOs, including nanoemulsions, liposomes, and solid lipid nanoparticles (SLNs), to enhance …
Cationic Liposomes: A Flexible Vaccine Delivery System for ...
WEBSep 12, 2018 · Cationic liposomes efficiently delivered the SLPs to DCs that subsequently activated SIINFEKL-specific CD8 + T-cells, indicating improved immunological activity of …
Liposomes: Structure, Biomedical Applications, and Stability …
WEBSep 9, 2021 · The spherical or multilayered spherical structures of liposomes are highly rich in lipid contents with numerous criteria for their classification, including structural …
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