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Learn more about Bing search results hereThis summary was generated by AI from multiple online sources. Find the source links used for this summary under "Based on sources".
Learn more about Bing search results hereOrganizing and summarizing search results for youCell maturation is a process that involves cell differentiation, body axis formation, tissue and organ development, and cell division. During development, cells use both intrinsic and extrinsic signals to "decide on" their behavior and identity. In the context of T cell responses to cognate antigens, maturation refers to alterations of the functional status of dendritic cells in direct response to multiple extrinsic innate signals derived from foreign organisms.2 Sources
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Cell maturation: Hallmarks, triggers, and manipulation
Jan 6, 2022 · A review article that explores how cells become specialized and adaptive through genetic and environmental cues. It defines maturation as a dynamic continuum of phenotypic states and discusses its implications for …
Cell Maturation: Hallmarks, Triggers, and Manipulation - PMC
How cells become specialized, or “mature”, is important for cell and developmental biology. While maturity is usually deemed a terminal fate, it may be more helpful to consider maturation not …
Cell maturation: Hallmarks, triggers, and manipulation - PubMed
Jan 20, 2022 · We discuss efforts to harness their chemical (nutrients, oxygen, and growth factors) and physical (mechanical, spatial, and electrical) triggers in vitro and in vivo and how …
β-Cell Maturation and Identity in Health and Disease - PMC
In this review, we summarize the current understanding of the mechanisms that coordinate the postnatal maturation of β-cells and define their functional identity. Furthermore, we discuss …
B-cell development: Maturation, activation and differentiation
See more on onlinebiologynotes.com- The development of plasma cell and memory B cells can be divided into three broad stages:
- Generation of mature, immunocompetent B-cells (maturation)
- Activation of mature B-cells and the differentiation of the activated B-cells, into plasma cells and memory B cells.
- These three stages can be divided into two phases:
- Estimated Reading Time: 9 mins
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specialized cell has been called ‘‘mature.’’ The term implies an ‘‘end state’’ of the completed development, reached by an age-dependent unidirectional progression (Figure 1A). Yet, …
Dendritic cell maturation: functional specialization through signaling ...
In response to activation by infection, injury or vaccination, NLT-cDC and LT-cDC undergo a program of maturation, which renders them capable of inducing the clonal expansion of …
Cell Maturation - an overview | ScienceDirect Topics
Maturation is an activation process that allows DCs to interact with innate immune cells (neutrophils, monocytes, macrophages, NK cells, and basophils) and adaptive immune cells to …
Identification of a chemical cocktail that drives the maturation of ...
Jan 2, 2024 · We identify a combination of four chemicals that promotes neuronal maturation by repressing epigenetic factors that inhibit it and stimulating activity-dependent factors that …
Dendritic cell maturation and cross‐presentation: …
Sensing of microbial stimuli causes DCs to enter a complex developmental program called ‘maturation’, which modifies DC morphology and functions profoundly. Maturation enhances transiently the capacity of DCs to take up …
Understanding heterogeneity of human bone marrow …
Jun 24, 2023 · Human bone marrow (BM) plasma cells are heterogeneous, ranging from newly arrived antibody-secreting cells (ASCs) to long-lived plasma cells (LLPCs). We provide single-cell transcriptional resolution of 17,347 BM …
T-cell maturation, activation and differentiation
Jul 30, 2020 · T-cell maturation: The migration of progenitor T-cells from the early sites of hematopoiesis to the thymus takes place at about day 11 of gestation in mice and in 8 th or 9 …
Differentiation of antigen-selected GC B cells. into memory B cells and plasma cells, the carriers of antibody-dependent (humoral) immunity. Affinity Maturation. 1. Distribution within ~2Kb from …
Dendritic Cell Maturation - R&D Systems
Read our article on Dendritic Cell Maturation. Antigen-presenting cells (APCs) are mature, immunologically competent dendritic cells (DCs).
B Cell Development and Maturation - PubMed
Since the identification of B cells in 1965 (Cooper et al. 1965), three has been tremendous progress in our understanding of B cell development, maturation and function. A number of B …
T Cell Maturation,Activation and Differentiation • Positive Selection-In thymus, permits survival of only those T cells whose TCRs recognize self-MHC molecules (self-MHC restriction) • …
Summary of T cell maturation ( ααββαβ T cells only)-Thymocytes enter the thymus as "double negative“ (markers?) - β-chain rearrangement (apoptosis of cells that fail to rearrange βββ …
Cell Maturation - an overview | ScienceDirect Topics
Maturation is a process through which DCs change their functional phenotype and is triggered by several environmental stimuli, such as cytokines, pathogens, factors released by necrotic cells …
β-Cell Maturation and Identity in Health and Disease - PubMed
Oct 30, 2019 · In this review, we summarize the current understanding of the mechanisms that coordinate the postnatal maturation of β-cells and define their functional identity. Furthermore, …
T-cell development in thymus | British Society for Immunology
The developing progenitors within the thymus, also known as thymocytes, undergo a series of maturation steps that can be identified based on the expression of different cell surface …
Cell maturation: Hallmarks, triggers, and manipulation
Jan 20, 2022 · A review article that proposes a dynamic view of cell maturation as a continuum of adaptive states set by genetic and environmental factors. It discusses the hallmarks of …
Chapter 16. Disorders of Cellular Growth, Differentiation,
Normally, growth and differentiation are controlled in such a way as to maintain the normal structure of a particular tissue. In tissues characterized by continuous cell loss (skin, intestinal …
T-Cell Development and Maturation - Interactive Biology, with …
T-cells play a crucial role in the adaptive immune response – our ability to recognize specific antigens on foreign invaders like pathogens. In this post, we’re going to look at how they …
3D Genome Structure Guides Sperm Development - UC Davis
5 days ago · The discoveries could also help scientists working on stem cell therapies, since coaxing a stem cell to become a neuron or heart cell requires shifting it from one genetic …
