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The dynamic world of the 8–17 DNAzyme - Nature
Jun 17, 2024 · High-precision DNA-based biocatalysts, known as DNA enzymes or DNAzymes, are experiencing a revival in biotechnological, analytical, and therapeutical applications.
A biologically stable DNAzyme that efficiently …
Mar 25, 2021 · Here we report a re-engineered version of the classic 10–23 DNAzyme that mediates persistent gene-silencing activity in cultured mammalian cells and simultaneously resists nuclease digestion.
DNA Catalysis: The Chemical Repertoire of …
Deoxyribozymes or DNAzymes are single-stranded catalytic DNA molecules that are obtained by combinatorial in vitro selection methods.
Designing in vivo active DNAzymes | Nature Chemistry
DNAmoreDB, a database of DNAzymes - PMC
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A promising nucleic acid therapy drug: DNAzymes and its …
DNAzymes: from creation in vitro to application in vivo
DNAzymes: Synthetic Enzymes Made of DNA | SpringerLink
Evidence of a General Acid/Base Catalysis Mechanism in the 8 …
Therapeutic DNAzymes: From Structure Design to …
Therapeutic DNAzymes have unceasingly intrigued the scientific community owing to their prosperous gene regulation capability. The efficacy of DNAzymes against many types of diseases has been extensively studied for over two …
DNAzymes – How Active DNA Biocatalysts That Destroy
The 8-17 DNAzyme can operate in a single active structure …
Single–Molecule Study of DNAzyme Reveals Its Intrinsic …
DNAzymes: Expanding the Potential of Nucleic Acid Therapeutics
Unraveling the Kinetics of the 10–23 RNA-Cleaving DNAzyme
DNAzymes: How active DNA molecules with therapeutic potential …
Biosensing with DNAzymes - PMC
Multivalent DNAzyme nanomachine generated by exonuclease III …