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  2. Lymphocyte Differentiation and Effector Functions - PMC

    Lymphocytes differentiate in primary lymphoid organs where they commit a lymphocytic lineage, express B or T cell receptors (BCR and TCR, resp.,), which are essential for cell survival and …

  3. Lymphocyte differentiation - Latest research and news | Nature

    May 1, 2025 · Lymphocyte differentiation is a process in which activated B cells or T cells become specialized immune cells. For example, B cells can give rise to antibody-producing cells and...

  4. Lymphocyte Differentiation - an overview | ScienceDirect Topics

    In this chapter, we discuss key epigenetic mechanisms controlling lymphocyte differentiation, from earlier stages (divergence from the myeloid branch) to the late acquisition of effector functions.

  5. Lymphocyte - Wikipedia

    All lymphocytes originate, during this process, from a common lymphoid progenitor before differentiating into their distinct lymphocyte types. The differentiation of lymphocytes follows …

  6. Lymphoid Hematopoiesis and Lymphocytes Differentiation and Maturation ...

    Jul 12, 2017 · Now, we will describe different classes of lymphocytes based on transcription factors expression and their cytokine secretion profile, associated to their differentiation status, …

  7. Development, differentiation and diversity of innate lymphoid cells

    Differentiation of cNK cells depends on sequential steps controlled by the transcription factors Id2, NFIL3 and Eomes. The development and maintenance of cNK cells require IL-15 signaling …

  8. AmiGO 2: Term Details for "lymphocyte differentiation" …

    A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. Source: …

  9. Nov 1, 2012 · Function of lymphocytes and its products range from the neutralization of pathogens with specific antibodies to the activation of macrophages and to direct cytotoxic activity.

  10. Lymphocyte Differentiation Section - National Institute on Aging

    We focus on three specific aspects: 1) general and antigen-specific T cell receptor (TCR) repertoires and their change with age; 2) transcriptional and epigenetic changes in CD8+ T …

  11. Innate lymphocytes—lineage, localization and timing of differentiation

    Feb 25, 2019 · In this review, we aim to shed light on the identities of innate lymphocytes through the lenses of cell lineage, localization, and timing of differentiation. Lymphocytes are a …

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