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  2. Orbitofrontal cortex - Wikipedia

    The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making. In non-human primates it consists of the …

  3. The orbitofrontal cortex: reward, emotion and depression - PMC

    The human medial orbitofrontal cortex represents many different types of reward, and the lateral orbitofrontal cortex represents non-reward and punishment. Not obtaining an expected reward …

  4. Medial Orbitofrontal Cortex - an overview | ScienceDirect Topics

    Electrical stimulation of the human orbitofrontal cortex can also produce reward and raise mood (Rao et al., 2018), and many of the sites stimulated in this study were in areas 13 and 11, …

  5. Orbitofrontal cortex: definition, structure and function | Kenhub

    Oct 30, 2023 · The orbitofrontal cortex refers to the ventral aspect of the frontal lobe that sits in the anterior cranial fossa, overlying the roof of the bony orbit. It forms part of the prefrontal …

  6. The human orbitofrontal cortex: linking reward to hedonic ... - Nature

    In recent neuroimaging studies of the cortical networks that mediate hedonic experience in the human brain, the orbitofrontal cortex has emerged as the strongest candidate for linking food …

  7. Orbitofrontal Cortex - Practical Psychology

    A prefrontal cortex portion of the brain, the orbitofrontal cortex (OFC), plays a role in cognitive functions. Emotion, taste, olfaction, and reward are assumed to be represented by the medial …

  8. The Medial Orbitofrontal Cortex Regulates Sensitivity to Outcome …

    Apr 20, 2016 · The medial orbitofrontal cortex (mOFC), a subregion of the ventromedial prefrontal cortex, is uniquely positioned to regulate this process. We trained mice to nose poke for food …

  9. Medial and orbital frontal cortex in decision-making and flexible ...

    The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of investigations of decision-making, behavioral flexibility, and social behavior.

  10. Roles of the medial and lateral orbitofrontal cortex in major ...

    Jan 12, 2024 · We describe evidence for dissociable roles of the medial and lateral orbitofrontal cortex (OFC) in major depressive disorder (MDD) from structure, functional activation, …

  11. Cytoarchitecture and probability maps of the human medial orbitofrontal ...

    Feb 1, 2016 · A cluster analysis of the cytoarchitectonical features of Fo1-Fo3, subgenual cingulate areas, BA12, lateral and medial areas of the frontopolar cortex, lOFC and areas of …