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- Mutations are changes to the nucleotide sequence of a DNA molecule1. They can be harmful, beneficial, or neutral to an organism1. Types of mutations include:
- Substitution mutations: where a single nucleotide is changed into another.
- Insertions and deletions: addition or removal of short stretches of nucleotide sequences.
- Chromosomal translocations: interchange of genetic parts from nonhomologous chromosomes.
- Chromosomal inversions: reversing the orientation of a chromosomal segment.
- Non-homologous chromosomal crossover: exchange of genetic material between non-sister chromatids.
- Interstitial deletions: removal of a segment of DNA from a single chromosome, apposing previously distant genes2.
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Key points:
- A mutation is any change to the nucleotide sequence of a DNA molecule. Some mutations arise as DNA is copied. ...
www.khanacademy.org/science/ms-biology/x0c5bb…The abnormal FIG-ROS fusion protein has constitutively active kinase activity that causes oncogenic transformation (a transformation from normal cells to cancer cells).
- Chromosomal translocations: interchange of genetic parts from nonhomologous chromosomes.
en.wikipedia.org/wiki/Mutation - See moreSee all on Wikipedia
Mutation - Wikipedia
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine … See more
Mutations can involve the duplication of large sections of DNA, usually through genetic recombination. These duplications are a major source of … See more
Mutation rates vary substantially across species, and the evolutionary forces that generally determine mutation are the subject of ongoing … See more
Although mutations that cause changes in protein sequences can be harmful to an organism, on occasions the effect may be positive in a given … See more
Four classes of mutations are (1) spontaneous mutations (molecular decay), (2) mutations due to error-prone replication bypass of See more
By effect on structure
The sequence of a gene can be altered in a number of ways. Gene mutations have varying effects on health depending on where they occur … See moreChanges in DNA caused by mutation in a coding region of DNA can cause errors in protein sequence that may result in partially or … See more
By introducing novel genetic qualities to a population of organisms, de novo mutations play a critical role in the combined forces of … See more
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