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  2. Mutations are changes to the nucleotide sequence of a DNA molecule1. They can be harmful, beneficial, or neutral to an organism1. Types of mutations include:
    1. Substitution mutations: where a single nucleotide is changed into another.
    2. Insertions and deletions: addition or removal of short stretches of nucleotide sequences.
    3. Chromosomal translocations: interchange of genetic parts from nonhomologous chromosomes.
    4. Chromosomal inversions: reversing the orientation of a chromosomal segment.
    5. Non-homologous chromosomal crossover: exchange of genetic material between non-sister chromatids.
    6. Interstitial deletions: removal of a segment of DNA from a single chromosome, apposing previously distant genes2.
    Learn more:

    Key points:

    • A mutation is any change to the nucleotide sequence of a DNA molecule. Some mutations arise as DNA is copied. ...
    www.khanacademy.org/science/ms-biology/x0c5bb…

    The abnormal FIG-ROS fusion protein has constitutively active kinase activity that causes oncogenic transformation (a transformation from normal cells to cancer cells).

    • Chromosomal translocations: interchange of genetic parts from nonhomologous chromosomes.
    en.wikipedia.org/wiki/Mutation
     
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    Mutation - Wikipedia

    In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine … See more

    Mutations can involve the duplication of large sections of DNA, usually through genetic recombination. These duplications are a major source of … See more

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    Mutation rates vary substantially across species, and the evolutionary forces that generally determine mutation are the subject of ongoing … See more

    Although mutations that cause changes in protein sequences can be harmful to an organism, on occasions the effect may be positive in a given … See more

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    Four classes of mutations are (1) spontaneous mutations (molecular decay), (2) mutations due to error-prone replication bypass of See more

    By effect on structure
    The sequence of a gene can be altered in a number of ways. Gene mutations have varying effects on health depending on where they occur … See more

    Changes in DNA caused by mutation in a coding region of DNA can cause errors in protein sequence that may result in partially or … See more

    By introducing novel genetic qualities to a population of organisms, de novo mutations play a critical role in the combined forces of … See more

     
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  4. Mutation | Definition, Causes, Types, & Facts | Britannica

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  14. An introduction to genetic mutations (video) | Khan Academy

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  22. What is a Gene Mutation? | Dana-Farber Cancer Institute

  23. Genetic Mutations | Types of Mutations | American Cancer Society

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  28. Home [www.yourgenome.org]