Common side effects

• Hypertension
• Musculoskeletal pain
• Headache disorder
• Dry nose
• Nasal congestion
• Nasal mucosa edematous
• Dyspnea
• Hypotension
• Hyperhidrosis
• Ventricular fibrillation
• Ventricular tachycardia
• Nausea
• Vomiting
• Irritability
• Constipation
• Toothache
• Muscle spasm

Other things to note

• Nasal dryness, swelling, or stuffy nose may occur. Muscle/joint pain or headache may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
• In someone who has been using an opioid regularly, withdrawal symptoms can happen suddenly after receiving this medication. Withdrawal symptoms may include body aches, fever, sweating, watering eyes, runny nose, sneezing, goose bumps, yawning, weakness, shivering/trembling, nervousness, restlessness, diarrhea, nausea/vomiting, stomach cramps, increased blood pressure, fast heartbeat. In babies younger than 4 weeks who have been receiving an opioid regularly, sudden opioid withdrawal may be life threatening if not treated the right way. Symptoms in babies may include seizures, crying more than usual, and muscle twitching/spasms.

• Tell doctor your complete medical history
• Protect from heat, light, & moisture
• Room temperature
• Check expiration date before using
• For auto-injector products : If available, read the patient package insert. Learn how to correctly use this medicine. Inject under skin or into muscle, but not into vein. Seek immediate medical help if this drug is used.
• For spray, non-aerosol products : For use in the nose. Use once and discard any extra medicine.
• For syringe products : Learn and use proper injection technique. May inject into vein, muscle or under the skin. Your condition will be monitored by your Dr. Check solution for particles or color change.

• For the nose.
• Do not freeze
• Protect from light

Before taking this medication, tell your doctor if you've had:

• Heart problems (such as irregular heartbeat, previous heart attack)