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  1. Lupus
    LupusAutoimmune disease
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  2. Systemic lupus erythematosus - Overview

    Verified Expert
    Also known as: lupus
    An autoimmune disease, with systemic manifestations including skin rash, erosion of joints or even kidney failure.
    Condition Highlight
    Urgent medical attention is usually recommended by healthcare providers
    Condition Highlight
    May be dangerous or life threatening
    How common is condition?
    Common (More than 200,000 cases per year in US)
    Is condition treatable?
    Treatments can help manage condition, no known cure
    Does diagnosis require lab test or imaging?
    Often requires lab test or imaging
    Condition Highlight
    More common in females
    See more

    Causes

    Verified Expert

    • Exact cause is not known, but it is believed that the following can cause the disease.
    • Genetics
    • Family history of close relative with lupus
    • Environmental Factors:
    • Exposure to ultra violet rays
    • Viruses
    • Medications or certain drugs
    • Emotional stress
    • Trauma
    • Hormones
    • Females are more commonly affected than men
    • Women during pregnancy are high risk of developing this condition
    • It is believed that estrogen, a sex hormone may play a role
    • The risk factors include:
    • Age: people between age of 15 - 45 years are more prone to develop lupus
    • Sex: Women are at higher risk to develop lupus

    See more

    Symptoms

    Verified Expert
    Seek immediate medical attention if you experience symptoms.

    Signs and symptoms may include:

    • Butterfly rash on the face
    • Appetite loss
    • Hair loss
    • Fever
    • Fatigue
    • Photosensitivity
    • Mouth ulcers
    • Unexplained Fever
    • Pericarditis
    • Pleuritis
    • Painful and swollen joints
    • Chest pain upon deep breathing
    • Swelling (edema) in legs or around eyes
    • Raynauds phenomenon
    • Chorea

    See more

    Treatment

    Verified Expert

    The main focus of the treament is to reduce and manage symptoms. Medications are given to control the symptoms.

    Medication

    Anti-inflammatory drugs: Given as oral medications, ointments, or intravenous injections.

    Ibuprofen . Naproxen . Diclofenac

    Steroid cream: Reduces the rashes.

    Triamcinolone . Fluocinolone

    Immuno suppressants: Reduces the rashes. Usually given in severe cases.

    Azathioprine . Methotrexate . Mycophenolate

    See more
    systemic lupus erythematosus_en
    Microsoft Start Health

    Diagnosis

    Verified Expert
    One or more of these tests may be recommended by your medical provider.
    Diagnosis is difficult as the symptoms vary from person to person. Doctor may suggest blood and urine tests to confirm the diagnosis.

    Common tests & procedures

    Complete blood count (CBC): To check the count of platelets, red blood cells.

    Erythrocyte sedimentation rate (ESR): Blood test where the time taken for RBC to settle at the bottom of test tube is faster in lupus than normal.

    Urine analysis: The high protein and red blood cells might indicate kidney damage due to lupus.

    Antibody test: Presence of Antinuclear antibody might indicate lupus. To confirm, Anti dsDNA antibodies are examined.

    Skin biopsy: Skin tissue is taken for further analysis to confirm the condition from affected sites.

    Kidney biopsy: Lupus can affect kidneys, biopsy helps to know the stage disease as well as treatment options.

    See more
    Source: Focus Medica. For informational purposes only. Consult a medical professional for advice. | Disclaimer: Opinions are from external health professionals and should not be considered as Microsoft's opinion or a substitute for professional help. Consult a health professional for medical advice.
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    Table of Contents
    Overview
    Causes
    Symptoms
    Who is affected by Lupus?
    Treatment
    Health guide
    Diagnosis
     

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  2. Lupus is a disease that occurs when your body's immune system attacks your own tissues and organs (autoimmune disease). Inflammation caused by lupus can affect many different body systems — including your joints, skin, kidneys, blood cells, brain, heart and lungs.

    Lupus - Symptoms & causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/lupus/sym…

    How common is lupus and who does it affect?

    • The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million people worldwide, have a form of lupus.

    More items

    Lupus facts and statistics | Lupus Found…

    www.lupus.org/resources/lupus-facts-and-statistics
     
  3. People also ask
    Do you know about lupus?
    While lupus is a widespread disease, awareness of the disease lags behind many other illnesses. 63% of Americans surveyed have never heard of lupus or know little or nothing about this disease and its symptoms beyond the name indicating there is significant opportunity and need for continued public education.

    Lupus facts and statistics | Lupus Foundation of America

    lupus.org
    How serious is Lupus?

    Dr. JYOTHI ELIZABETH Roy

    MBBS · 3 years of exp

    Lupus refers to an autoimmune connective tissue disorder that can affect the joints, skin, kidneys, blood cells, brain, heart, and lungs. Triggers for lupus include sunlight, certain drugs, and infections. Complications include renal involvement- glomerulonephritis and renal failure, neurological features-headaches, dizziness, behavior changes, vision problems, and strokes or seizures, cardiovascular features like myocarditis, and endocarditis and increased risk of cardiovascular diseases, pulmonary features- pleurisy, pleural effusion, thromboembolism, and hematological features-anemia and an increased risk of bleeding or blood clotting.
    Q&A: Systemic Lupus Erythematosus
    bing.com
    Who is affected by Lupus?
    Lupus strikes mostly women of childbearing age. However, men, children, and teenagers develop lupus, too. Ninety percent (90%) of people living with lupus are women. Most people with lupus develop the disease between the ages of 15-44.

    Lupus facts and statistics | Lupus Foundation of America

    lupus.org
    Can anyone develop lupus?
    Anybody can develop lupus, but it’s clear that some people have a higher risk of developing the condition than others. The diagnostic process for a condition like lupus can be long and complicated, because, like many autoimmune conditions, lupus can affect a wide range of organs and body systems. The result: An equally wide range of symptoms.

    9 Tips for Living With Lupus - Cleveland Clinic Health Essentials

    health.clevelandclinic.org
    Feedback
     
  4. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/lupus

    Lupus - Symptoms & causes - Mayo Clinic

     
  5. WebMD
    https://www.webmd.com/lupus/arthritis-lupus

    Lupus: Symptoms, Causes, Complications, and Treatment - WebMD

  6. Medical News Today
    https://www.medicalnewstoday.com/art…

    What is my life expectancy if I have lupus? - Medical …

    WEBFeb 21, 2024 · Most people with lupus can expect to live a long and full life. Factors such as an early diagnosis, following a treatment plan, and attending screenings for health complications may improve ...

  7. Cleveland Clinic
    https://health.clevelandclinic.org/tips-for-living-with-lupus

    9 Tips for Living With Lupus - Cleveland Clinic Health Essentials

  8. Cleveland Clinic
    https://my.clevelandclinic.org/health/diseases/4875

    Lupus: Symptoms & Treatment - Cleveland Clinic

  9. Explore Person with Lupus

  10. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Lupus - Diagnosis & treatment - Mayo Clinic

  11. Lupus Foundation of America
    https://www.lupus.org/understanding

    Understanding Lupus | Lupus Foundation of America

  12. CDC
    https://www.cdc.gov/lupus

    Lupus | Lupus | CDC - Centers for Disease Control …

    WEBSigns and Symptoms. People with Lupus. Lupus Types. Public Health. Sign up for Email Updates. Lupus is a disease that can affect people of all ages, races, and ethnicities. The signs and symptoms mimic those of …

  13. nih.gov
    https://www.niams.nih.gov/health-topic…

    Systemic Lupus Erythematosus (Lupus) - Who gets …

    WEBJul 2, 2024 · Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body. Lupus occurs when the immune system, which normally helps protect the body …

  14. Verywell Health
    https://www.verywellhealth.com/lupus-8694321

    Lupus: Physical Feeling, Symptom Start, Treatment - Verywell …

  15. Lupus Foundation of America
    https://www.lupus.org/resources/what-i…

    What Is Lupus? - Lupus Foundation of America

    WEBJul 31, 2020 · 9 out of 10. people with lupus are women. Read more facts and statistics about lupus. What causes lupus? No one knows what causes lupus — but lupus and other autoimmune diseases do run in …

  16. CDC
    https://www.cdc.gov/lupus/signs-symptoms

    Symptoms of Lupus | Lupus | CDC - Centers for Disease Control …

  17. Healthline
    https://www.healthline.com/health/lupus

    Lupus: What Is It, Symptoms, Treatment, Rash, and More

  18. Lupus Foundation of America
    https://www.lupus.org/resources/prognosis-and-life-expectancy

    Prognosis and life expectancy | Lupus Foundation of America

  19. Everyday Health
    https://www.everydayhealth.com/lupus

    What Is Lupus? Symptoms, Causes, Diagnosis, and Treatment

  20. HSS | Hospital for Special Surgery
    https://www.hss.edu/condition-list_lupus.asp

    Lupus Symptoms, Diagnosis and Treatment | HSS Rheumatology

  21. Healthline
    https://www.healthline.com/health/lupus/early-signs

    10 Early Signs of Lupus: How to Identify Them - Healthline

  22. nih.gov
    https://www.niams.nih.gov/health-topics/lupus/...

    Systemic Lupus Erythematosus (Lupus): Diagnosis, Treatment, …

  23. Johns Hopkins Lupus Center
    https://www.hopkinslupus.org/lupus-info/lupus-affects-body

    How Lupus Affects the Body - Johns Hopkins Lupus Center

  24. nih.gov
    https://www.niams.nih.gov/.../living-with-lupus

    Living With Lupus: Health Information Basics for You and Your …

  25. Lupus Foundation of America
    https://www.lupus.org/resources/lupus-facts-and-statistics

    Lupus facts and statistics | Lupus Foundation of America

  26. Lupus.net
    https://lupus.net/life-expectancy

    What Is the Life Expectancy for Someone With Lupus?

  27. Medical News Today
    https://www.medicalnewstoday.com/articles/lupus-diet

    Lupus diet: What to include and what to avoid

    WEBMar 25, 2024 · Beneficial foods. Foods for side effects. Foods to avoid. Summary. Experts do not recommend a particular diet for people with lupus, but some research suggests that the Mediterranean diet may...

  28. Medical News Today
    https://www.medicalnewstoday.com/articles/lupus-medication

    Medications for lupus: Antimalarials, steroids, NSAIDs, and more

  29. neurolaunch.com
    https://neurolaunch.com/lupus-brain-fog

    Lupus Brain Fog: Understanding and Managing Cognitive …

  30. The Rheumatologist
    https://www.the-rheumatologist.org/article/bringing-lupus-into-the-light

    Bringing Lupus into the Light - The Rheumatologist