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  2. Picato ( ingenol) works by causing the death of certain cells in the body. Picato gel is used to treat actinic keratosis (warty overgrowths of skin) on the face, scalp, arms, and legs. Picato gel may also be used for purposes not listed in this medication guide. Use Picato gel exactly as prescribed by your doctor.

    Picato is available as a gel which is applied to skin areas affected by actinic keratosis. It is used when the outer layer of the affected skin is not thickened or raised. Actinic keratosis is caused by too much sunlight exposure and can turn into skin cancer. Picato has been authorised for use in the EU since November 2012.
    www.ema.europa.eu/en/news/ema-suspends-picat…

    Picato is used to treat actinic keratosis, a scaly, crusty lesion on the skin that may be red or yellow in color. We have also received reports of cases involving severe eye injuries and skin reactions associated with the application of Picato gel.

    www.fda.gov/drugs/drug-safety-and-availability/fda …
    Picato has already been taken off the market and is therefore no longer a treatment option for actinic keratosis. Other treatment options for actinic keratosis include topical diclofenac, fluorouracil and imiquimod, as well as photodynamic therapy, cryotherapy, curettage or excisional surgery.
    www.ema.europa.eu/en/news/risks-picato-actinic-k…
     
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  4. Picato Gel: Uses, Dosage, Side Effects, Warnings - Drugs.com

     
  5. Picato Topical: Uses, Side Effects, Interactions, Pictures

  6. Generic Name: Ingenol mebutate

    Common side effects

    • Blistering skin
    • Superficial skin ulcer
    • Pruritus of skin
    • Skin irritation
    • Periorbital edema

    Common side effects

    • Blistering skin
    • Superficial skin ulcer
    • Pruritus of skin
    • Skin irritation
    • Periorbital edema
    • Pharyngitis
    • Headache disorder
    • Erythema
    • Skin scaling
    • Skin crusting
    • Skin swelling
    • Pain
    • Acute pain at drug application site
    • Treatment site sequelae
    • Application site infection


    Tell your doctor right away if you have any serious side effects, including

    • Blisters, pus, or ulcers at the application site

    Get medical help right away if you have any very serious side effects, including

    • Painful rash


    Tell your doctor right away if you have any serious side effects, including

    • Blisters, pus, or ulcers at the application site

    Get medical help right away if you have any very serious side effects, including

    • Painful rash
    • Vision changes

    A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including

    • Rash
    • Itching/swelling
    • Severe dizziness
    • Trouble breathing

    Other things to note

    • Skin redness, itching, irritation, flaking/peeling, crusting, pain, or swelling commonly occur at the site of application. Eye/eyelid, nose, or throat irritation or headache may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

    For informational purposes only. Consult a medical professional for advice.

    Source: First Databank Learn more

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  7. FDA Drug Safety Communication: FDA warns of severe adverse …

  8. Picato (Ingenol Mebutate): Side Effects, Uses, Dosage ... - RxList

  9. Ingenol mebutate gel - Picato. Used to treat solar keratosis - Patient

  10. Picato Gel: Actinic Keratosis Uses, Side Effects & Dosage

  11. EMA suspends Picato as a precaution while review of skin cancer …

  12. Risks of Picato for actinic keratosis outweigh benefits

  13. FDA Approves Picato® (ingenol mebutate) Gel, the …

    WEBJan 25, 2012 · Picato® gel is indicated for the topical treatment of actinic keratosis. To date, 18 clinical trials have been completed for the use of Picato® gel, from phase I trials through pivotal phase III...

  14. Ingenol mebutate (Picato) for actinic keratosis: Overview

    WEBApr 15, 2013 · Ingenol mebutate has been approved for the treatment of actinic keratosis where the skin has stayed flat and is not too callused – referred to as non-hyperkeratotic and non-hypertrophic actinic keratosis.

  15. Ingenol mebutate gel - DermNet

  16. EMA review of Picato concludes medicine’s risks outweigh its …

  17. Picato: Uses, Taking, Side Effects, Warnings - Medicine.com

  18. Ingenol mebutate gel (Picato ): suspension of the licence due to …

  19. Actinic Keratosis Treatment - The Skin Cancer Foundation

  20. Picato (ingenol mebutate): Drug Basics and Frequently Asked

  21. Picato (Ingenol topical) Topical: Uses, Dosage & Side Effects

  22. Picato: Package Insert / Prescribing Information - Drugs.com

  23. Picato - referral | European Medicines Agency (EMA)

  24. Common skin lesions. Topical treatment of photodamage - DermNet

  25. Picato® gel | NHMRC - National Health and Medical Research …

  26. Picato Side Effects: Common, Severe, Long Term - Drugs.com

  27. Picato Dosage Guide - Drugs.com