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Below it is a large cell that could be a monocyte or reactive lymphocyte. The cytoplasm is colorless except at the periphery; a common feature of reactive lymphocytes. The evenly distributed nuclear chromatin is slightly more dense than usual in monocytes but less dense than in reactive lymphocytes.

Mar 11, 2024 · Basically, monocytes are like first responders that respond quickly and non-specifically to antigens. Lymphocytes are like specialized back-ups that operate more slowly. They typically take over when monocytes aren’t killing the antigens effectively.

2. Reactive (activated) lymphocytes vs. monocytes. Reactive lymphocytes – particularly big ones – can look a lot like monocytes. Again, the key is to look at the chromatin. Large reactive lymphocytes are usually immunoblasts, and as such, they have a big nucleolus (or two).

Dec 4, 2020 · Some general points; monocytes are often larger, cytoplasm of monocytes is a somewhat paler blue. Reactive lymphocytes usually have extra blue borders at the sites where they touch erythrocytes. I have a site with some morphology and …

For lymphocytosis with reactive morphology, in the differential is not only infectious mononucleosis, the classic one and relatively common in practice, but also other viral infections (some cases of acute HIV and viral hepatitis; rarer would be adenovirus, HHV-6, rubella, roseola, mumps, chickenpox), especially acute cytomegalovirus, for which ...

Oct 11, 2024 · Multi-clonal means they come from the duplication of many different cells. Lymphocytes that come from more than one cell are considered “reactive,” so they typically point to an infection. Lymphocytes that are clones of a single cell, …

reactive lymphocyte : 2-4x larger than a mature RBC; Increased amount of light blue cytoplasm; Nucleoli usually absent; Cytoplasm is usually indented by surrounding RBCs; Granules are usually absent. so in conclusion : mono : cell is larger , lower N\C ratio , finer nuclear chromatin; reactive lamphocyte :cell is smaller , condensed chromatin ...

Feb 2, 2025 · Reactive lymphocytes, primarily T cells and B cells, recognize specific antigens presented by antigen-presenting cells, leading to an adaptive immune response. In contrast, monocytes are phagocytic cells involved in the innate immune system, engulfing pathogens and debris through a process called phagocytosis.

There are three main types of lymphocytes: B cells, T cells, and natural killer cells. Monocytes, on the other hand, are part of the innate immune system and act as phagocytes, engulfing and destroying foreign particles and pathogens.

Monocytes are the tools for Innate Immunity. Lymphocytes are tools for Adaptive Immunity. Also Read: Difference Between Granulocytes and Agranulocytes. This was a brief introduction to the difference between monocyte and lymphocytes.