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Small RNA - Wikipedia
Small RNA (sRNA) are polymeric RNA molecules that are less than 200 nucleotides in length, and are usually non-coding. RNA silencing is often a function of these molecules, with the most common and well-studied example being RNA interference (RNAi), in which endogenously expressed microRNA (miRNA) or exogenously derived small interfering RNA (siRNA) induces the degradation of complementary messenger RNA. Other classes of small RNA have been identified, including piwi-interacting RNA
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Small RNAs: classification, biogenesis, and function - PubMed
Feb 28, 2005 · Eukaryotes produce various types of small RNAs of 19-28 nt in length. With rapidly increasing numbers of small RNAs listed in recent years, we have come to realize how …
- Author: Kim Vn
- Publish Year: 2005
Ribo-gnome: The Big World of Small RNAs - Science
Sep 2, 2005 · Small RNA guides—microRNAs, small interfering RNAs, and repeat-associated small interfering RNAs, 21 to 30 nucleotides in length—shape diverse cellular pathways, from chromosome architecture to stem cell …
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Exploring the expanding universe of small RNAs - Nature
Apr 12, 2022 · The world of small noncoding RNAs (sncRNAs) is ever-expanding, from small interfering RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical …
Small and long non-coding RNAs: Past, present, and …
Nov 14, 2024 · A review of the history, biogenesis, evolution, function, and crosstalk of small RNAs and lncRNAs in eukaryotes. Learn how these regulatory ncRNAs have shaped the field of RNA biology and beyond, and what are the …
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Everything you wanted to know about small RNA but were afraid …
Apr 21, 2008 · A small number of microRNAs are expressed mainly in embryonic stem (ES) cells, and attention has naturally focused on their roles in maintaining the pleuripotent …
Exploring Small RNA: Types, Functions, Regulation, and …
Apr 11, 2024 · Small RNA-mediated gene regulation stands as a cornerstone process, intricately controlling gene expression across multiple tiers, encompassing transcriptional, post …
A guide to the biogenesis and functions of endogenous small
3 days ago · Many new small RNA species and their derived fragments have been recently identified in animals. This Review discusses the biogenesis and functions of both structural …
Novel functions for small RNA molecules - PubMed Central (PMC)
Small RNAs are short (~ 18 to 30 nucleotides), non-coding RNA molecules that can regulate gene expression in both the cytoplasm and the nucleus via post-transcriptional gene silencing …
Small RNAs: Classification, Biogenesis, and Function
Feb 1, 2005 · A review of small RNAs, non-coding RNAs of 19-28 nt in length, that mediate gene silencing in eukaryotes. Learn about the different types, origins, and mechanisms of small …
Small RNAs with Mighty Functions - RNA, the …
Sep 20, 2022 · The ability of natural or modified small siRNAs, delivered directly or via a vector that produces a ‘small/short hairpin RNA’ (shRNA), to inhibit gene expression specifically and potently in plants and animals has been widely …
Small RNA modifications: regulatory molecules and potential ...
Jun 22, 2023 · Small RNAs (also referred to as small noncoding RNAs, sncRNA) are defined as polymeric ribonucleic acid molecules that are less than 200 nucleotides in length and serve a …
Small silencing RNAs: an expanding universe - Nature
Small RNAs — including miRNAs, siRNAs and piRNAs — differ in their biogenesis, modes of target regulation and biological functions.
Exploring the expanding universe of small RNAs - PMC
The world of small non-coding RNAs (sncRNAs) is ever-expanding, from siRNAs, miRNAs, piRNAs to the recently emerging noncanonical sncRNAs derived from longer structured RNAs …
Small RNAs in bacteria and archaea: who they are, what they do …
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs, thereby …
DASHR - Database of small human noncoding RNAs
To get started, click on the Search to search small RNA by name/ID, genomic coordinates, sequence, or click Browse to explore small RNA expression and annotation information.
The small RNA world - The Company of Biologists
Dec 1, 2003 · Small RNAs and evolutionarily conserved RNA-mediated silencing pathways have established a new paradigm for understanding eukaryotic gene regulation and revealed novel …
Small RNAs: An expanding world with therapeutic promises
Sep 1, 2023 · Small non-coding RNAs (sncRNAs), such as microRNAs (miRNAs), small interfering RNAs (siRNAs), PIWI-interacting RNAs (piRNAs), and transfer RNA (tRNA)-derived …
Small RNAs - Latest research and news | Nature
Jan 15, 2025 · Small RNAs are a type of non-coding RNA (ncRNA) molecule that are 50 250 nucleotides in length. They are often involved in regulating the translation of target RNAs …
Small RNAs – secrets and surprises of the genome
The discovery of miRNAs relied mainly on size fractionation to isolate small RNAs from total RNAs, ligation of the small RNAs to 5′ and 3′ adaptors, and RT-PCR of the ligation products to …
Small CAG Repeat RNA Forms a Duplex Structure with Sticky …
Jan 14, 2025 · Biomolecular condensation lays the foundation of forming biologically important membraneless organelles, but abnormal condensation processes are often associated with …
The expanding world of small RNAs | Nature
Jan 23, 2008 · Small RNAs, non-coding RNAs consisting of 20 to 30 nucleotides, regulate many biological processes. There may be tens of thousands of such regulatory RNAs in the …
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