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  1. Nature
    https://www.nature.com › articles

    Satellite repeat transcripts modulate heterochromatin ... - Nature

    • Heterochromatin maintains genome integrity and function, and is organised into distinct nuclear domains. Some of these domains are proposed to form by phase separation through the accumulation of HP1ɑ. M… See more

    Introduction

    Functional compartmentalisation of the genome segregates repetitive, gene-poor regions into constitutive heterochromatin1. Establishing and maintaining the appropriat… See more

    Nature
    Results

    Constitutive heterochromatin forms liquid-like condensates in mouse embryonic stem … See more

    Nature
    Discussion

    Our study demonstrates that noncoding satellite RNA modulates the physical properties and nuclear organisation of heterochromatin. Satellite repeat elements are highly t… See more

    Nature
    Methods

    Cell culture
    Male, E14Tg2a mouse ESCs (129P2/OlaHsdl passages 19–28)82 were cultured in ESC media containing DMEM supplement… See more

    Nature
    What are the different types of satellite RNA?
    Three different subgroups of these satellites are distinguished: Large satellite RNAs that are mRNA, small linear satellite RNAs and circular satellite RNAs. This category comprises satellites with genomes that are 0.8 to 1.5 kb in size and encode a non-structural protein that, at least in some cases, is essential for satellite RNA multiplication.
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    Introduction
    Results
    Discussion
    Methods
    What are the different types of satellite RNA?
     

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  2. eLife
    https://elifesciences.org › articles

    Major satellite repeat RNA stabilize heterochromatin retention of ...

     

  3. Images of Major satellite RNA

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  4. Nature
    https://www.nature.com › articles

    LSM1-mediated Major Satellite RNA decay is required for ... - Nature

  5. nih.gov
    https://pmc.ncbi.nlm.nih.gov › articles

    Satellite RNAs: emerging players in subnuclear architecture and …

  6. royalsocietypublishing.org
    https://royalsocietypublishing.org › doi

    Pericentric major satellite transcription is essential for …

    Nov 8, 2023 · RNA-FISH revealed that major satellite transcripts are expressed at key stages of mouse oocyte meiosis and remain associated with pericentric heterochromatin domains at the germinal vesicle stage, metaphase-I bivalents …

  7. nih.gov
    https://pmc.ncbi.nlm.nih.gov › articles

    Pericentric major satellite transcription is essential for meiotic ...

  8. People also ask
    Are satellite RNAs expressed in mouse oocyte meiosis?
    We have recently demonstrated that major satellite RNAs are expressed during key stages of mouse oocyte meiosis and remain bound to pericentric heterochromatin domains , and expression of pericentric satellite transcripts (HS2, HS3) has also been described in human oocytes .

    Pericentric major satellite transcription is essential for meiotic

    royalsocietypublishing.org
    What is a satellite RNA?
    Each class of satellite RNAs is a mixture of heterogeneous RNAs with a common major repeat sequence. The difficulty in obtaining precise nucleotide sequences of satellite RNAs using a canonical short‐read sequencer owing to their repetitiveness has hindered research on the role of specific satellite RNAs.

    Satellite RNAs: emerging players in subnuclear architecture and gene

    pmc.ncbi.nlm.nih.gov
    What are the different types of satellite RNA?
    Three different subgroups of these satellites are distinguished: Large satellite RNAs that are mRNA, small linear satellite RNAs and circular satellite RNAs. This category comprises satellites with genomes that are 0.8 to 1.5 kb in size and encode a non-structural protein that, at least in some cases, is essential for satellite RNA multiplication.

    Satellite RNA - an overview | ScienceDirect Topics

    sciencedirect.com
    Which RNA reads mapped to the consensus sequence of major satellite repeats?
    MiSeq RNA sequencing shows that in the MSR-reverse RNA-enriched sample, the majority of the reads mapped to the consensus sequence of major satellite repeats (GSAT_MM), and for the LINE L1MdA 5′UTR-forward RNA-enriched sample, the majority of the reads mapped to two subtypes of the L1MdA subfamily (L1MdA_I and L1MdA_III, Supplementary Figure S2B).

    m6A RNA methylation of major satellite repeat transcripts facilitates

    academic.oup.com
    What role does pericentric major satellite RNA play in oocyte meiosis?
    Proposed model for the functional roles of pericentric major satellite RNA during oocyte meiosis. Pericentric major satellite RNAs play functional roles in regulating chromosome stability, meiotic progression as well as spindle stability.

    Pericentric major satellite transcription is essential for meiotic

    royalsocietypublishing.org
    Are satellite RNAs a subclass of lncRNAs?
    Based on the current knowledge of their roles, we propose naming transcripts encoded by HSat DNA regions “satellite RNAs” as a distinct subclass of lncRNAs and provide an account of the current understanding of the roles of satellite RNAs in gene regulation and MLO formation, together with their possible involvement in physiology and disease.

    Satellite RNAs: emerging players in subnuclear architecture and gene

    embopress.org
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  9. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    Pericentric major satellite transcription is essential for meiotic ...

  10. Oxford Academic
    https://academic.oup.com › nar › article

    m6A RNA methylation of major satellite repeat transcripts …

  11. nih.gov
    https://pmc.ncbi.nlm.nih.gov › articles

    Satellite DNAs in Health and Disease - PMC

    Mouse pericentromeric major satellite DNA transcripts form RNA:DNA hybrids, which enable the retention of the Heterochromatin Protein 1 (HP1) proteins and methyltransferases SUV39h1 and SUV39h2 [34,35], while enrichment of …

  12. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    m6A RNA methylation of major satellite repeat transcripts …

  13. Cell Press
    https://www.cell.com › developmental-cell …

    A Strand-Specific Burst in Transcription of Pericentric …

    Oct 19, 2010 · Remarkably, our qualitative analysis using RNA-FISH shows that major satellite transcripts exhibit unexpected strand-specific expression patterns and localization. Whereas Forward transcripts accumulate during S-phase, …

  14. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    Satellite RNAs: emerging players in subnuclear architecture

  15. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov › pmc › articles

    Major satellite repeat RNA stabilize heterochromatin retention of ...

  16. elifesciences.org
    https://cdn.elifesciences.org › articles
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    Major satellite repeat RNA stabilize heterochromatin …

  17. EMBO Press
    https://www.embopress.org › doi › full

    Satellite RNAs : emerging players in subnuclear ... - The EMBO …

  18. nih.gov
    https://pmc.ncbi.nlm.nih.gov › articles

    m6A RNA methylation of major satellite repeat transcripts …

  19. ScienceDirect
    https://www.sciencedirect.com › ... › satellite-rna

    Satellite RNA - an overview | ScienceDirect Topics

  20. sciencedirect.com
    https://www.sciencedirect.com › science › article › pii

    The Nuclear Matrix Protein SAFB Cooperates with Major Satellite …

  21. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov › pmc › articles

    LSM1-mediated Major Satellite RNA decay is required for …

  22. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    Major satellite repeat RNA stabilize heterochromatin retention of ...

  23. Oxford Academic
    https://academic.oup.com › nar › advance-article › doi › nar

    Diversity and evolution of viroids and viroid-like agents with …