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You should not use ozanimod if you are allergic to it, or if you have certain serious heart conditions, especially:
- recent (within the past 6 months) heart failure, heart attack, stroke, "mini-stroke" or TIA, chest pain (unstable angina), or other serious heart problem;
- "AV block" or sick sinus syndrome (unless you have a pacemaker); or
- severe untreated sleep apnea (breathing stops during sleep).
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