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  1. Plague - Overview

    Verified Expert
    Also known as: black death
    An infectious disease caused by the bacterium yersinia pestis, transmitted by fleas. This causes fever, headache and fatigue.
    Condition Highlight
    Urgent medical attention is usually recommended by healthcare providers
    Condition Highlight
    Can be dangerous or life threatening if untreated
    How common is condition?
    Very rare (Fewer than 20,000 cases per year in US)
    Is condition treatable?
    Treatable by a medical professional
    Does diagnosis require lab test or imaging?
    Requires lab test or imaging
    Time taken for recovery
    Can last several days or weeks
    Is condition preventable by vaccine?
    May be preventable by vaccine
    How is condition transmitted?
    Transmitted through airborne exposure
    Condition Highlight
    Common for ages 20 and older
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    Causes

    Verified Expert

    • The causes include:
    • Plague is caused by the bacterium Yersinia pestis
    • The bacteria are transmitted by fleas which have fed on infected rodents (rats, rabbits, squirrels)
    • The fleas can spread by handling infected animals, eating infected animals or by scratches or bites from infected domestic cats
    • A rare deadliest form, pneumonic plague can be spread from person to person by coughing The bacterium into The air

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    Symptoms

    Verified Expert
    Seek immediate medical attention if you experience symptoms.

    Bubonic Plague Symptoms

    • Fever
    • Chills
    • Headache
    • Muscle pain
    • General weakness
    • Seizures
    • Painful, swollen lymph glands which are referred to as buboes

    Pneumonic Plague Symptoms

    • Breathing difficulties
    • Chest pain
    • Cough
    • Fever
    • Headache
    • Overall weakness
    • Bloody sputum

    Septicemic Plague Symptoms

    • Abdominal pain
    • Diarrhea
    • Nausea and vomiting
    • Fever and Chills
    • Extreme weakness
    • Bleeding
    • Shock
    • Gangrene

    See more
    Is plague a bacterial infection?
    Plague is an acute bacterial infection caused by Yersinia pestis. Although effective antimicrobials are available, plague still has high mortality because... After action review (AAR) results: plague response in Madagascar helped improve national preparedness...
    who.int

    Treatment

    Verified Expert

    Treatment options include antibiotics and supportive care.

    Medication

    Antibiotics: Strong antibiotics are prescribed to fight the infection.

    Gentamicin . Doxycycline . Ciprofloxacin . Levofloxacin

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    plague_en
    Microsoft Start Health

    Diagnosis

    Verified Expert
    One or more of these tests may be recommended by your medical provider.
    Diagnosis is done by testing the body fluids for the presence of the bacteria.

    Common tests & procedures

    Blood test: Samples are collected to detect the presence of the bacterium.

    Sputum culture test: Samples are collected to detect the presence of the bacterium.

    See more
    Source: Focus Medica. For informational purposes only. Consult a medical professional for advice. | Disclaimer: Opinions are from external health professionals and should not be considered as Microsoft's opinion or a substitute for professional help. Consult a health professional for medical advice.
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    Table of Contents
    Overview
    Causes
    Symptoms
    Is plague a bacterial infection?
    Treatment
    Health guide
    Diagnosis
     

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  2. You can get plague:

    • By getting bitten by fleas or lice. Fleas bite rats or other animals infected with pestis, then bite you.
    • Directly from an infected animal. You can get infected with Y. pestis by touching body fluids or tissues of an infected animal.
    • From another person. If someone has Y. pestis in their lungs (pneumonic plague), you can get infected if they cough or sneeze on you.

    Plague: Types, History, Causes & Prevention - Cleveland Clinic

    my.clevelandclinic.org/health/diseases/17782-plague
    my.clevelandclinic.org/health/diseases/17782-plague
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  3. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Plague - Symptoms and causes - Mayo Clinic

     
  4. WHO
    https://www.who.int/.../fact-sheets/detai…

    Plague - World Health Organization (WHO)

    Jul 7, 2022 · Plague is a very severe disease in people, particularly in its septicaemic (systemic infection caused by circulating bacteria in bloodstream) and pneumonic forms, with a case-fatality ratio of 30% to 100% if left untreated.

  5. Wikipedia
    https://en.wikipedia.org/wiki/Plague_(disease)

    Plague (disease) - Wikipedia

  6. CDC
    https://www.cdc.gov/plague/signs-sym…

    Signs and Symptoms of Plague | Plague | CDC

    Plague is a serious illness. If you are experiencing symptoms like those listed here, seek immediate medical attention. Prompt treatment with the correct medications is critical to prevent complications or death. Signs and symptoms …

  7. CDC
    https://www.cdc.gov/plague/causes

    How Plague Spreads | Plague | CDC - Centers for Disease …

  8. Explore plague infected person

  9. Cleveland Clinic
    https://my.clevelandclinic.org/health/diseases/17782

    Plague: Types, History, Causes & Prevention - Cleveland Clinic

  10. CDC
    https://www.cdc.gov/plague

    About Plague | Plague | CDC - Centers for Disease Control and …

  11. National Geographic
    https://www.nationalgeographic.com/science/article/the-plague

    Plague (Black Death) bacterial infection information and ...

  12. WHO
    https://www.who.int/health-topics/plague

    Plague - World Health Organization (WHO)

  13. WHO
    https://www.who.int/news-room/questions-and-answers/item/plague

    Plague - World Health Organization (WHO)

  14. nih.gov
    https://www.niaid.nih.gov/diseases-conditions/plague

    Plague - National Institute of Allergy and Infectious Diseases (NIAID)

  15. Emergency Preparedness and Response | CDC
    https://emergency.cdc.gov/agent/plague/factsheet.asp

    Facts about Pneumonic Plague - Emergency Preparedness and …

  16. The Merck Manuals
    https://www.merckmanuals.com/home/infections/...

    Plague and Other Yersinia Infections - Plague and Other Yersinia ...

  17. CDC
    https://www.cdc.gov/plague/resources/Human-Plague-508.pdf
    [PDF]

    Human Plague Transmission from person to person

  18. Cleveland Clinic
    https://my.clevelandclinic.org/health/diseases/21590

    Bubonic Plague (Black Death): What Is It, Symptoms,

  19. Emergency Preparedness and Response | CDC
    https://emergency.cdc.gov/agent/plague/faq.asp

    Frequently Asked Questions (FAQ) About Plague - CDC

  20. WebMD
    https://www.webmd.com/a-to-z-guides/plague-faq

    Plague: Bubonic, Pneumonic, and Septicemic - WebMD

  21. MedicineNet
    https://www.medicinenet.com/plague_facts/article.htm

    Plague (Black Death) Symptoms, Types, Treatment, History

  22. Harvard Health
    https://www.health.harvard.edu/a_to_z/plague-yersinia-pestis-a-to-z

    Plague (Yersinia Pestis) - Harvard Health

  23. History
    https://www.history.com/topics/middle-ages/black-death

    Black Death ‑ Causes, Symptoms & Impact - HISTORY

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