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  2. In eukaryotic chromosomes, DNA is wound around histone proteins, and then, it is further compacted by supercoiling and folding. In prokaryotic chromosomes, DNA is supercoiled and compacted by nucleoid-associated proteins.
    www.visiblebody.com/learn/biology/dna-chromoso…
    Whereas eukaryotes wrap their DNA around proteins called histones to help package the DNA into smaller spaces, most prokaryotes do not have histones (with the exception of those species in the domain Archaea). Thus, one way prokaryotes compress their DNA into smaller spaces is through supercoiling (Figure 1).
    www.nature.com/scitable/topicpage/genome-packa…
    A higher level of DNA packaging is present in both organisms with significant differences. Prokaryotes lack true histone proteins, unlike the eukaryotic chromosomes. The complex interaction between DNA and histones prepares a chromosomal structure in eukaryotes.
    geneticeducation.co.in/difference-between-prokary…
     
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