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- Lyophilization (freeze-drying) is used for the following reasons123:
- Preserving biological activity: It is especially beneficial for sensitive materials like proteins, enzymes, and vaccines.
- Long-term storage: Lyophilization stabilizes bacterial cultures for extended storage periods.
- Minimizing damage: The gentle process minimizes the risk of loss of activity or damage to sensitive compounds.
- Water removal: It removes water from perishable materials, extending shelf life or making them more convenient for transport.
Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Lyophilization is especially beneficial for preserving the biological activity of sensitive materials, such as proteins, enzymes and vaccines. The gentle freezing and drying process in lyophilization minimizes the risk of loss of activity or damage to these sensitive compounds.www.promegaconnections.com/an-introduction-to-l…Lyophilization, or freeze-drying of bacterial cultures, stabilizes the cultures for long-term storage while minimizing the damage that may be caused by strictly drying the sample. Many microorganisms survive well when lyophilized and can be easily rehydrated and grown in culture media, after prolonged periods of time in storage.www.thoughtco.com/lyophilization-preserving-biolo…Lyophilization is a water removal process typically used to preserve perishable materials, to extend shelf life or make the material more convenient for transport. Lyophilization works by freezing the material, then reducing the pressure and adding heat to allow the frozen water in the material to sublimate.www.millrocktech.com/lyosight/lyobrary/what-is-lyo… - People also ask
What is lyophilization and why is it used?
Lyophilization, also known as freeze-drying, is a process used for preserving biological material by removing the water from the sample, which involves first freezing the sample and then drying it, under a vacuum, at very low temperatures. Lyophilized samples may be stored much longer than untreated … See more
The sample is frozen, which means the water in the product is converted to ice, thereby the phase has changed from liquid to solid. Slow pre-freezing will produce lager ice crystals, which are easier to lyophilize, whilst fast pre-freezing results in smaller crystals. See more
In the second stage of lyophilization the sublimation process starts. The ice formed in the pre-freeze step is removed from the sample by the direct transition of the “solid” ice to a … See more
Finally, any residual water present, which is strongly bound to the molecules of the sample, is converted to vapour and removed from the … See more
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