Jane Horrocks was born

Jane Horrocks was nominated for the 1993 Olivier Award for Best Actress for the title role in the stage play The Rise and Fall of Little Voice

Jane Horrocks reprised her stage role in the 1998 screen adaptation, Little Voice, which earned nominations for the Golden Globe Award for Best Actress - Motion Picture Musical or Comedy, the BAFTA Award for Best Actress in a Leading Role, the Satellite Award for Best Actress - Motion Picture Musical or Comedy, the Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Leading Role - Motion Picture, and the British Independent Film Award for Best Actress.

Jane Horrocks appeared in the television series Fifi and the Flowertots (2005–2010)

Jane Horrocks appeared in the film Sunshine on Leith (2013)

Jane Horrocks played Ella Khan in the London revival of East Is East at Trafalgar Studios as part of Jamie Lloyd's Trafalgar Transformed season.

Jane Horrocks gave a reading at VE Day 70: A Party to Remember in Horse Guards Parade, London that was broadcast live on BBC1. She supplied the voice of the Tubby Phone in the reboot of the popular British children's television series Teletubbies.

Jane Horrocks starred in the Sky One sitcom Trollied, as Julie Cook (2011–2015). She starred in Richard Jones's critically acclaimed production of The Good Soul of Szechuan at the Young Vic in 2008. She was reunited with Jones in a new musical production of Annie Get Your Gun, which opened at the Young Vic in October 2009. At London's Young Vic, in 2016's If You Kiss Me, Kiss Me, Horrocks revisited the songs of her youth to sing versions of tracks by the likes of Joy Division, The Smiths, Buzzcocks, and The Human League. She also appeared in the film Absolutely Fabulous: The Movie (2016)

Jane Horrocks joined the cast of the British premiere production of play Nachtland at the Young Vic theatre, directed by Patrick Marber.