Ranganath Rao, an archaeologist and professor visits a library in Greece and through a book, written by Ptolemy, he discovers that Shri Krishna, before the end of Dvapara Yuga, entrusted his friend and counceller Uddhava with his anklet, which is equipped with all the solutions for deadly problems, humans are going to face in the succeeding Kali Yuga.

In Hyderabad, Karthikeya "Karthik", now a doctor who believes in science and logic is suspended for slapping a Mayor, who had attempted to perform a Yagna in the ICU for his son. At the same time, his father fractures his leg and an ox hits the plant of Tulasi in front of their house. Considering all the inauspicious occurrences, Karthik's mother believes that her family is being punished for not being able to fulfil a vow made to Shri Krishna, a few years ago. Therefore, Karthik takes her to Dwarka where his uncle Sadananda, an ardent devotee of Shri Krishna, lives. One night, Karthik crosses paths with a mortally wounded Ranganath Rao, who tries to tell something to him. When Karthik leaves to fetch an auto rikshaw for taking him to hospital and returns, he fails to find Rao. The following day, Karthik's mother goes missing and he searches for her with his uncle. He is arrested by the Police, who accuse him of murder and ask him what Rao had told him. When Karthik tells them that he was not able to interpret his words, the Police refuse to believe him. A girl, Mugdha, revealed to be Rao's granddaughter rescues Karthik from Police custody. A mysterious man attacks Karthik but stops when he sees the idol of Shri Krishna.

Karthik, Mugdha and Sadananda visit a sage to find about the man and learns that he belongs to the clan of Abheeras, an exiled community who resorted to dacoity but worshipped Shri Krishna. They wouldn't let the people, who tries to hinder with Krishna's belongings, live. Karthik finds his mother and determined to solve the mystery; he advises her to be safe at a 11-days-long Pravachan. They visit Rao's office in Bet Dwarka and read a letter, written by him. Rao had found that the anklet was hidden by Uddhava, who left behind clues to reach it, as the right person is destined to get that. For centuries, several people had tried to find the anklet but to no avail. Pallava King Suryavarman reached the closest and told the penultimate clue to Ptolemy, who hid the object with clue in Krishna Thatakam, which Rao was trying to utter when he met Karthik. Santanu, a professor in search of the anklet, kills Rao with evil intentions and was the one, responsible behind Karthik's arrest. Karthik finds a peacock-shaped object in Krishna Thatakam and Mugdha decodes the Sanskrit inscription written on it, that leads them to Govardhan Hill. The trio hire Suleman to take them to Govardhana Hill, Mathura without being caught by Police. Upon arriving there, they are apprehended by villagers, who are greedy for the prize money announced by Santanu for Karthik and Mugdha. They manage to convince the villagers of their objectives and climbs the hill to find an entrance, that they open using the peacock-shaped object and retrieve a telescope from it.

Next morning, Mugdha escapes with the telescope leaving Karthik, Sadananda and Suleman. Santanu apprehends the trio and leaves them in the desert to die but Mugdha arrives and rescues them, revealing that she had gone to her friend for finding about a person, who would help them in solving the mystery. Together, the foursome leave to Himachal Pradesh for meeting a blind philosopher Dr. Dhanvantari, who explains that Rao and Santanu were a part …

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