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- Target cells, also known as codocytes or leptocytes, is a unique morphology of red blood cells characterized by a central, round hemoglobin area surrounded by a rim of paler staining. This distinctive appearance is caused by an increased surface-to-volume ratio of the RBCs due to excess membrane or decreased hemoglobin content.
microbiologie-clinique.com/en/target-cells.html - People also ask
The Pathogenesis of Spherocytes and Leptocytes (Target Cells)
The Leptocyte or Target Cell. Compared with the spherocyte and the attention shown it, its opposite number, the target cell has been neglected. In 1877 Litten 28 described a “pessary …
- Author: William H. Crosby
- Publish Year: 1952
Target Cells - American Society of Hematology
Jan 13, 2016 · Target cells, or codocytes, have an excess of cell membrane relative to cell volume. Macrocytic target cells can be seen in liver disease, and microcytic target cells may …
Leptocytes and target cells - LabCE
Dec 30, 2011 · Leptocytes and target cells. The peripheral blood smear of HbH disease presented before is reviewed in the upper photograph. As mentioned, these leptocytes are pale-staining …
Analytical Review: The Pathogenesis of Spherocytes and …
Feb 1, 1952 · The target cell, which is a thin erythrocyte, is the antithesis of the spherocyte. Compared with the normal red cell its volume is found to be small for the surface area. The …
Anemia Workup: Approach Considerations, Investigation for
Aug 24, 2023 · Approach Considerations. The first step in the diagnosis of anemia is detection with reliable, accurate tests so that important clues to underlying disease are not overlooked …
leptocytes (Cytokines & Cells Encyclopedia - COPE)
In contrast to normal red blood cells, which show a clear central area, leptocytes are elongated or oval in shape and are pale-staining with hemoglobin, which is confined to a thin flat layer near …
Leptocyte - Oxford Reference
Oct 29, 2024 · n. a red blood cell (erythrocyte) that is wafer-thin, generally large in diameter, and displays a thin rim of haemoglobin at the periphery with a large area of central pallor. …
Leptocyte | definition of leptocyte by Medical dictionary
lep·to·cyte. A target or Mexican hat cell, that is, an unusually thin or flattened red blood cell with a central rounded area of pigmented material, a middle clear zone that contains no pigment, and …
Peripheral Blood Smear - Clinical Methods - NCBI …
Leptocytes (or wafer cells) are thin, flat cells with the hemoglobin at the periphery of the cell. Sickle cells (drepanocytes) are elongated, sometimes crescent-shaped, erythrocytes with pointed ends. Elliptocytes (ovalocytes) range from …
Laboratory Approach to Anemia - IntechOpen
Dec 20, 2017 · Based on determination of the red blood cell mass, anemia can be classified as either relative or absolute. Relative anemia is characterized by a normal total red blood cell …
Three-minute peripheral blood film evaluation: The erythron
Dec 1, 2004 · A leptocyte (codocyte, target cell) is an RBC with excess cell membrane that forms a shape often referred to as having a Mexican hat appearance (Figure 10). Leptocytes are …
Leptocytes (Wafer Cells) - Medicalalgorithms.com
Leptocytes are an uncommon finding in peripheral blood smears. Features of a leptocyte: (1) flat, thin and wafer-like. (2) hypochromic with a large area of central pallor and a thin rim of …
Leptocyte - Oxford Reference
a red blood cell (*erythrocyte) that is wafer-thin, generally large in diameter, and displays a thin rim of haemoglobin at the periphery with a large area of central pallor. Leptocytes are seen in …
Spherocytes – A Laboratory Guide to Clinical Hematology
Cell Description: Round red blood cells that lack an area of central pallor. Cells often appear darker and smaller than a normocytic red blood cell. 1. Cell Formation: Formation of …
Shape changes - eClinpath
Target cells (codocytes or leptocytes) have a “lump” of hemoglobinized cytoplasm within the area of normal central pallor, causing them to resemble a “bullseye” target. The ability to assume …
Target cells (Concept Id: C0221284) - National Center for …
Target cells (codocytes) have a centrally located disk of hemoglobin surrounded by an area of pallor with an outer rim of hemoglobin adjacent to the cell membrane giving the cell the …
BOC 5-7 Flashcards - Quizlet
The red blood cell about 5 µm in diameter that stains bright red and shows no central pallor is a: (H72) •Spherocyte •Leptocyte •Microcyte •Macrocyte
Leptocyte - Oxford Reference
May 4, 2024 · a red blood cell (erythrocyte) that is wafer-thin and generally large in diameter, with the haemoglobin concentrated in a thin rim at the periphery. Leptocytes are seen in certain …
Significance of the target cell (leptocyte) in peripheral blood …
The target cell is commonly found in the peripheral blood smears of the Gold Coast African in numbers greater than 4 per cent. The target cell does not appear to be a hereditary anomaly …
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