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Local circuits actively shape the functional organization of hippocampal area CA1 and its computational role in memory formation, properties that have now been measured with …

We show that the majority of lamina I neurons with locally branching axons fall into the multipolar (with ventrally protruding dendrites) and flattened (dendrites limited to lamina I) …

The medial local circuit neurons, which supply the lower motor neurons in the medial ventral horn, have axons that project to many spinal cord segments; indeed, some project to targets along …

Aug 8, 2014 · Most cortical interneurons, also termed local circuit neurons (LCNs), primarily use the neurotransmitter GABA (γ-aminobutyric acid) to modulate neural activity.

Local circuits in the hippocampus are comprised of excitatory connections from principal cells to interneurons and mainly inhibitory interneuronal connections onto principal cells. A smaller …

Mar 1, 1994 · In the cerebral cortex, local circuit neurons provide critical inhibitory control over the activity of pyramidal neurons, the major class of excitatory efferent cortical cells. The calcium …

The local circuit neurons receive sensory inputs as well as descending projections from higher centers. Thus, the circuits they form provide much of the coordination between different …

Jun 25, 2002 · We conclude that NK-1-bearing local circuit neurons of the striatum regulate the differential responses of striatal projection neurons to dopamine-mediated signaling. …

Dec 4, 2013 · Here we identified the parvalbumin interneurons (PVNs) as a prominent component of the M/T presynaptic landscape by using an improved rabies-based transsynaptic tracing …

Local cortical circuit activity in vivo comprises a complex and flexible series of interactions between excitatory and inhibitory neurons.

In this review, we outline support for the framing of the frontoparietal network as a distinct control network, in part functioning to flexibly interact with and alter other functional brain networks. …

Jan 15, 2025 · Nearly 50 years ago, neuroscientists discovered cells within the brain’s hippocampus that store memories of specific locations. These cells also play an important role …

Feb 1, 1994 · During the development of the cerebellar cortex (E14-E15), neurons arise from two different ventricular zones, Purkinje cells from the ventricular germinal zone in the fourth …

Jan 9, 2025 · Summary: Scientists have uncovered how developing neurons migrate from the germinal zone, a process critical for proper brain circuit formation. They identified a “push-pull” …

We review the characteristics and function of multiple somatosensory, association, and other networks. We discuss the concept of critical nodes in the brain and how the neurosurgeon can …

4 days ago · The latent circuit model captures task-related neural activity in the low-dimensional subspace spanned by the columns of Q, with dynamics within this subspace generated by the …

1 day ago · Many laboratories use two-photon microscopy through commercial suppliers, or homemade designs of considerable complexity. The integrated nature of these systems …

Here we use an unbiased approach for activity-dependent RNA sequencing to identify warm-sensitive neurons (WSNs) within the preoptic hypothalamus that orchestrate the homeostatic …

2 days ago · The St. Louis Circuit Attorney’s Office charged Perkins Tuesday with unlawful use of a weapon, a felony. He is held without bond. Perkins lives with his grandmother in north St. …

1 day ago · But over the past several months, the St. Louis Circuit Attorney’s Office conducted a review of the case, including an accident reconstruction, office spokeswoman Christine …